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The map label for this gene is frr [H]

Identifier: 225630154

GI number: 225630154

Start: 368756

End: 369313

Strand: Reverse

Name: frr [H]

Synonym: WRi_003430

Alternate gene names: 225630154

Gene position: 369313-368756 (Counterclockwise)

Preceding gene: 225630155

Following gene: 225630153

Centisome position: 25.54

GC content: 31.36

Gene sequence:

>558_bases
ATGTTAAATGAAATAAAAGCTAAAACAAAAGAAAGAATGCTAAAAACTATTCAGTCCTTTCATGATGATATTAAAGGCGT
ACGCACTGGTAGAGCTAGCGCATCGTTGCTTGATGGTATAGTTGTAAATATCTATGGTGGACATCAAAAGTTAAATCAGG
TTGCAGGTGTTTCGGTTATAGATAACAAAACTCTATCAATTAAAATTTGGGATATTAATGTTGTCGGTGAAGTGAAAAAT
GCTATATTAAATGCCAACTTGAATTTAAATCCTGTTGTTGAGGGCAATACCATACGTATAGCTCTTCCGGACTTAACACA
AGAAACCCGTGAAAAATTAGTGAAATTATTGCATCAGTTTGCTGAAAATGCACGGATTGCCATTAGAAATATACGTAGAG
ATATTATGGAAGAAACAGAAAAAATGAAGGAAAATAAAGAAATCTCAGAAGATGATTTTCATGGTGCTAAAAAGGAAATA
CAAAATATTACTGATAATAATATAAAAAAAATTGATGGTGAATTGTCCATCAAAGAAAAGGATATACTGAATCACTAA

Upstream 100 bases:

>100_bases
CCAATTATAGTTTTTTCTTTGAAGGGAGAAAAAATAGTCAATATTATTAAGGGTCAAGGTACTTATACTATAGTTTCAGA
TTGTAAACATTAGGTAATTT

Downstream 100 bases:

>100_bases
ATGATATGGAGAAAGCTTACATAGCAAATGATGTCATTCCAGTGCTTGACACTGGAATCCAGTCTTTACTATACAACTAT
CTGATGCACTTGTTTGAAAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLNEIKAKTKERMLKTIQSFHDDIKGVRTGRASASLLDGIVVNIYGGHQKLNQVAGVSVIDNKTLSIKIWDINVVGEVKN
AILNANLNLNPVVEGNTIRIALPDLTQETREKLVKLLHQFAENARIAIRNIRRDIMEETEKMKENKEISEDDFHGAKKEI
QNITDNNIKKIDGELSIKEKDILNH

Sequences:

>Translated_185_residues
MLNEIKAKTKERMLKTIQSFHDDIKGVRTGRASASLLDGIVVNIYGGHQKLNQVAGVSVIDNKTLSIKIWDINVVGEVKN
AILNANLNLNPVVEGNTIRIALPDLTQETREKLVKLLHQFAENARIAIRNIRRDIMEETEKMKENKEISEDDFHGAKKEI
QNITDNNIKKIDGELSIKEKDILNH
>Mature_185_residues
MLNEIKAKTKERMLKTIQSFHDDIKGVRTGRASASLLDGIVVNIYGGHQKLNQVAGVSVIDNKTLSIKIWDINVVGEVKN
AILNANLNLNPVVEGNTIRIALPDLTQETREKLVKLLHQFAENARIAIRNIRRDIMEETEKMKENKEISEDDFHGAKKEI
QNITDNNIKKIDGELSIKEKDILNH

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=30.4597701149425, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI291042689, Length=162, Percent_Identity=30.8641975308642, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=42.1621621621622, Blast_Score=157, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=27.1676300578035, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20927; Mature: 20927

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEIKAKTKERMLKTIQSFHDDIKGVRTGRASASLLDGIVVNIYGGHQKLNQVAGVSVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCHHHHHHHHCCEEE
DNKTLSIKIWDINVVGEVKNAILNANLNLNPVVEGNTIRIALPDLTQETREKLVKLLHQF
CCCEEEEEEEEEEEHHHHHHHHHCCCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHH
AENARIAIRNIRRDIMEETEKMKENKEISEDDFHGAKKEIQNITDNNIKKIDGELSIKEK
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHH
DILNH
HHCCC
>Mature Secondary Structure
MLNEIKAKTKERMLKTIQSFHDDIKGVRTGRASASLLDGIVVNIYGGHQKLNQVAGVSVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEECCHHHHHHHHCCEEE
DNKTLSIKIWDINVVGEVKNAILNANLNLNPVVEGNTIRIALPDLTQETREKLVKLLHQF
CCCEEEEEEEEEEEHHHHHHHHHCCCCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHH
AENARIAIRNIRRDIMEETEKMKENKEISEDDFHGAKKEIQNITDNNIKKIDGELSIKEK
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHH
DILNH
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA