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The map label for this gene is pyrH [H]

Identifier: 225630155

GI number: 225630155

Start: 369321

End: 370064

Strand: Reverse

Name: pyrH [H]

Synonym: WRi_003440

Alternate gene names: 225630155

Gene position: 370064-369321 (Counterclockwise)

Preceding gene: 225630156

Following gene: 225630154

Centisome position: 25.59

GC content: 34.54

Gene sequence:

>744_bases
ATGTTTCCCTCAATAAATGAAAAAAGCGAAATAAAATATTCCAGAGTGTTATTTAAAATTTCTGGTGAAGCTTTAATGGG
GTCACAGTCTTTTGGCTATGATATGGGAATAATAAGCCAATTGTGCAAAGATATAGCTGATATTAACAGGCTTGGAGTTC
AGGTATGTATTGTTGTTGGTGGTGGTAATATCTTTCGTGGCACATCTGCGTCTTTAAGTGGCTGTGAAAGAGCAAGTAGT
GATTATATTGGAATGCTTGCAACTATAATCAATGCTTTAATTTTACAAAACTTTTTAGAAAAAAATTTAATAGCTTCTAG
GGTATTATCTGCAATACCCATGGCCACTGTATGTGAACCTTACATAAGAAGGAAAGCTATTCGTCATTTAGAAAAAGGTA
GAGTGGTAATTTTTGCAGCAGGCACAGGCAACCCATTTTTTACTACAGATACAGCTGCAGCCTTACGTGCTGTTGAAATG
AATTGTGATGTTATTCTAAAGGGTACGCAAGTAAATGGTGTATACTCCGCTGATCCGAAAAAAAATGAGGATGCTGTAAT
GTATGATAGGCTTTCTTACACGGATTTATTGACTCGTGATTTAAAAGTTATGGATGCATCAGCAATTTCACTTGCTCGTG
AGAATTCTATTCCAATTATAGTTTTTTCTTTGAAGGGAGAAAAAATAGTCAATATTATTAAGGGTCAAGGTACTTATACT
ATAGTTTCAGATTGTAAACATTAG

Upstream 100 bases:

>100_bases
ATGAAGGTTTCTGATTTTATAAAATCAAGCGAGGTGAGTGCTGTTAAACTCTCTAATTACAAGTTACTTGTTTTGGGTGG
TGCAAACTAAATGGTAAAAA

Downstream 100 bases:

>100_bases
GTAATTTATGTTAAATGAAATAAAAGCTAAAACAAAAGAAAGAATGCTAAAAACTATTCAGTCCTTTCATGATGATATTA
AAGGCGTACGCACTGGTAGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MFPSINEKSEIKYSRVLFKISGEALMGSQSFGYDMGIISQLCKDIADINRLGVQVCIVVGGGNIFRGTSASLSGCERASS
DYIGMLATIINALILQNFLEKNLIASRVLSAIPMATVCEPYIRRKAIRHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEM
NCDVILKGTQVNGVYSADPKKNEDAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIIVFSLKGEKIVNIIKGQGTYT
IVSDCKH

Sequences:

>Translated_247_residues
MFPSINEKSEIKYSRVLFKISGEALMGSQSFGYDMGIISQLCKDIADINRLGVQVCIVVGGGNIFRGTSASLSGCERASS
DYIGMLATIINALILQNFLEKNLIASRVLSAIPMATVCEPYIRRKAIRHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEM
NCDVILKGTQVNGVYSADPKKNEDAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIIVFSLKGEKIVNIIKGQGTYT
IVSDCKH
>Mature_247_residues
MFPSINEKSEIKYSRVLFKISGEALMGSQSFGYDMGIISQLCKDIADINRLGVQVCIVVGGGNIFRGTSASLSGCERASS
DYIGMLATIINALILQNFLEKNLIASRVLSAIPMATVCEPYIRRKAIRHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEM
NCDVILKGTQVNGVYSADPKKNEDAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIIVFSLKGEKIVNIIKGQGTYT
IVSDCKH

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=44.206008583691, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26903; Mature: 26903

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPSINEKSEIKYSRVLFKISGEALMGSQSFGYDMGIISQLCKDIADINRLGVQVCIVVG
CCCCCCCCHHHHEEEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEE
GGNIFRGTSASLSGCERASSDYIGMLATIINALILQNFLEKNLIASRVLSAIPMATVCEP
CCCEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YIRRKAIRHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEMNCDVILKGTQVNGVYSADPK
HHHHHHHHHHHCCCEEEEEECCCCCCEECCHHHHHHHEECCCEEEEECCEECCEEECCCC
KNEDAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIIVFSLKGEKIVNIIKGQGTYT
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCEE
IVSDCKH
EECCCCC
>Mature Secondary Structure
MFPSINEKSEIKYSRVLFKISGEALMGSQSFGYDMGIISQLCKDIADINRLGVQVCIVVG
CCCCCCCCHHHHEEEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEE
GGNIFRGTSASLSGCERASSDYIGMLATIINALILQNFLEKNLIASRVLSAIPMATVCEP
CCCEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YIRRKAIRHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEMNCDVILKGTQVNGVYSADPK
HHHHHHHHHHHCCCEEEEEECCCCCCEECCHHHHHHHEECCCEEEEECCEECCEEECCCC
KNEDAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIIVFSLKGEKIVNIIKGQGTYT
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCEE
IVSDCKH
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA