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The map label for this gene is putA [H]

Identifier: 225629994

GI number: 225629994

Start: 148436

End: 151576

Strand: Direct

Name: putA [H]

Synonym: WRi_001480

Alternate gene names: 225629994

Gene position: 148436-151576 (Clockwise)

Preceding gene: 225629993

Following gene: 225630004

Centisome position: 10.27

GC content: 37.03

Gene sequence:

>3141_bases
ATGATAAGCTCTATACAAGAACCTAATGAACTCAGAAAACGTTTACAAGGATTTTATCGTACTGATGAAAAGAGTTATAT
ACGTTATCTTGTAGAAAAAGCAGAGCTTTCGGCTGATTCAAAAAATAGAATTTATAATATTGCAAAACAAGTTATTGAAA
AAATCAAACACAATAAATTAAGTATTGTAGATTCCTTTATGCAGCAATACTCGCTTTCCAATGATGAAGGAATAGCGCTT
ATGTGTCTTGCTGAGTCACTACTTAGAATACCAGATGATTATACAATAGACGAGCTAATCAAAGATAAAATTGCCAATCA
AGAATGGAGTAAATATTTAGGATATTCTTCTTCATTGTTCGTCAATGCTTCCATGTGGAGTTTAATGATAGGTAGCAGTA
TATTGAGAGATAATGAAGGCGATTCGAAGTTCTATTACGCAATTTCTAAGTTACTTAAGAATTTAGGAGAACCGATCATT
CGCAAAGCAGTAAAACAAGCAATGTCTATGCTTGGTAATCATTTTGTTGTTGGAGAAACCATAGAAGAAGCTTTAAGGTA
CGCAAAACTAGATGACAATAGTAAGTTTTTATACTCTTTTGATATGCTTGGCGAAGCTGCTCACACAACTGAGGATGCAG
AAGAGTATTTTAATTCGTACATGCACTCAATAAAAGCTATAGGTGAATCCACTGAAATAAATGATTGTTTTAAATCCCAT
GGAATTTCAATCAAACTTTCTGCTTTACACCCACGTTATGAATTTAGTCAATTTGGCCGAATTGCTGGTGAGATATTCAC
TAAGGTTTTAGAGCTCTGCCGCGAGGCAAAAAAATACAACATTTCACTATGCATAGACGCAGAAGAAACAGAAAGGCTTG
AAATTTCCTTAATCTTGTTTGAACAATTACGGCTTGATGAATCACTTTCTGAGTGGGAAGGGCTCGGCTTGGCTGTACAA
GCATATCAAAAACGTGCTTTATCTGTTCTTGACTTTGTAGAGGATGTTGCTATTCGATCAAAGCACAAAATTATGGTGAG
GCTTGTAAAAGGTGCATATTGGGATTCAGAAATCAAGTGTACGCAAGAATTGGGATTAAATGATTACTCAGTATTTACAA
GAAAAAGCTATACTGACGTATCTTACCTCGTGTGCGCACAGAAACTTTTGAGTAAACCAAACAGCTTTTACCCATGCTTT
GGAACTCATAACGTCTATACTTTTGCTTCTATCATGGAACTTGCTGATAAAAACCACCCTGGATTTGAATTTCAACGCTT
ACATGGAATGGCAAAAGACTTATATGATTATGCAATGTCAGAGCTTGCAACAAATGTTAGCTGTCGTGTCTACGCACCCG
TTGGGGAACATAGTGACTTGTTGCCTTATCTTATAAGACGCCTTCTTGAAAATGGAGCTAATAGTTCGTTTGTTAATCAA
ATAAGTAATCCTAACGTTAAAATCGATGAGTTAATTTCAGATCCACTGGAAAAAGCTATAAATTTTAATTATGAACCTCA
TCCAGGCATTCCATTACCACAAGATATTTTGGGACCAGAAAGAAAAAATTCCTTGGGGATGGATATTAGTGATTCTGTGA
TAGTCTCACAATTTGCAGATGATATAAAGGGTTTTAGTGAAAAAAAGTGGCAAGTTGGACCAATAATTGATGGAAAAGCA
CTATTTGATAATGCTGAATTTATCGAAGTAGTGAATCCTGCACATTTGGAAAATGTAATTGGAGAAGTGTCAAGTGCAAC
AAGCGATCAAGCTTTAAACGCTCTTGAAATAGCACATAGTGCTTTTGCTAAGTGGCAGAATGTTTCAGCAGAAGAGCGCG
CTAAATGCCTTGAAAAAGCTGCAGATTTGCTTGAGGAAAGGATGAAAGAGTTAATTTACATTCTGATTGTGGAAGCAGGA
AAAATTTTATCCGATGCAATAGCAGAAGTAAGAGAGGCAATCGACTTTCTGCGTTATTATGCAATGATAGCAAAAAATGA
ACTGAGCGACTGGAAAAAATTGCCGGGCCCAACAGGTGAAGATAACTTCATCTTTTTTGAAGGCAGAGGAGTTTTCTTAT
GCATATCACCGTGGAATTTTCCGCTCGCTATCTTCATTGGGCAGGTCTCAGCTGCACTTGCAGCAGGTAATGCAGTGCTG
GCAAAACCGGCAGAGCAAACGCCGATTATTGCCTACGAAGCTGTTAAGATACTACATGAAGCTGGGATACCAAAGAATGT
GTTACACCTCATTCCTGGGGATGGTGGATATTTAGGCAAAATATTAGTTCCAGACAATAGAATTGCCGGAGTAGCTTTTA
CTGGCTCAACACAAACTGCTCAAATAATCAATAAAATGCTTGCAAATAGGGATGGTCCTATCGTACCACTTATTGCTGAA
ACAGGAGGGCTCAATGCTATGATAGTTGATAGCTCTGCTCTCTTAGAGCAAGTGACTACGGATGTTTTGCTTTCTGCGTT
TCGCAGCGCTGGCCAACGCTGTTCTGCGCTTAGAGTGCTGTTTATTCAAGAGGACATAGCAGAGAAGCAGATAAAAATGA
TATGCGGTGCAGCGCAAGAACTCAAGATTGGTGACCCAATACAACTTAGTACTGATATTGGTCCAATAATTGATAAAGCA
TCTATCGATATGCTCACTCAACATACGCAAAAAATGTCAGAGGATAAAGATTCAAATCTGTTATTTAAAGTACCCATGGA
TACAAATTCTCATAATGGTTATTTCTTTCCTCCATATATTTATGAGATACAAAAAATTTCGCAATTAAAGCAAGAAGTAT
TTGGTCCTATTTTACATATCATACGTTTTAACAAGTCACAATTAAATGAAGTTATAAGTGATATAAATAGTACTGGATAT
GGGCTTACGTTTTCTTTGCAGAGTCGTATACAAAGTCAAATTGACACTATAAGTAAAAAAATATCAGTTGGAAATGTCTA
CATCAACCGTAACCAGATAGGTGCAGCAGTTGGGATACAACCATTTGGTGGTAGAGGACTATCTGGCACTGGGCCAAAAG
CTGGTGGTCCTCATTATTTACAGCGTTTTTCTACAGAAAAAGTTGTAAGTGTTAACACTACAGCATTTGGTGGTAACACT
ACACTTATGTGTTTGGATTAA

Upstream 100 bases:

>100_bases
AGCCCTGATCCCTTTGTAAATAGCAATTTGCTCTGCGCAAAGTTATGATATAATTTCACCATACATATGGTGTCGGAGTA
TTTTTTGGAGATAATTATAT

Downstream 100 bases:

>100_bases
TTTGCGGGCCCTAATTTTTCTTACCCCTAAACTAGACGTTCGTGCAGTTATGTACACAGCGCTAAAATCCGAAAAGGACC
AGCTCATGCACTGAAATAAA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1046; Mature: 1046

Protein sequence:

>1046_residues
MISSIQEPNELRKRLQGFYRTDEKSYIRYLVEKAELSADSKNRIYNIAKQVIEKIKHNKLSIVDSFMQQYSLSNDEGIAL
MCLAESLLRIPDDYTIDELIKDKIANQEWSKYLGYSSSLFVNASMWSLMIGSSILRDNEGDSKFYYAISKLLKNLGEPII
RKAVKQAMSMLGNHFVVGETIEEALRYAKLDDNSKFLYSFDMLGEAAHTTEDAEEYFNSYMHSIKAIGESTEINDCFKSH
GISIKLSALHPRYEFSQFGRIAGEIFTKVLELCREAKKYNISLCIDAEETERLEISLILFEQLRLDESLSEWEGLGLAVQ
AYQKRALSVLDFVEDVAIRSKHKIMVRLVKGAYWDSEIKCTQELGLNDYSVFTRKSYTDVSYLVCAQKLLSKPNSFYPCF
GTHNVYTFASIMELADKNHPGFEFQRLHGMAKDLYDYAMSELATNVSCRVYAPVGEHSDLLPYLIRRLLENGANSSFVNQ
ISNPNVKIDELISDPLEKAINFNYEPHPGIPLPQDILGPERKNSLGMDISDSVIVSQFADDIKGFSEKKWQVGPIIDGKA
LFDNAEFIEVVNPAHLENVIGEVSSATSDQALNALEIAHSAFAKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAG
KILSDAIAEVREAIDFLRYYAMIAKNELSDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGGYLGKILVPDNRIAGVAFTGSTQTAQIINKMLANRDGPIVPLIAE
TGGLNAMIVDSSALLEQVTTDVLLSAFRSAGQRCSALRVLFIQEDIAEKQIKMICGAAQELKIGDPIQLSTDIGPIIDKA
SIDMLTQHTQKMSEDKDSNLLFKVPMDTNSHNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINSTGY
GLTFSLQSRIQSQIDTISKKISVGNVYINRNQIGAAVGIQPFGGRGLSGTGPKAGGPHYLQRFSTEKVVSVNTTAFGGNT
TLMCLD

Sequences:

>Translated_1046_residues
MISSIQEPNELRKRLQGFYRTDEKSYIRYLVEKAELSADSKNRIYNIAKQVIEKIKHNKLSIVDSFMQQYSLSNDEGIAL
MCLAESLLRIPDDYTIDELIKDKIANQEWSKYLGYSSSLFVNASMWSLMIGSSILRDNEGDSKFYYAISKLLKNLGEPII
RKAVKQAMSMLGNHFVVGETIEEALRYAKLDDNSKFLYSFDMLGEAAHTTEDAEEYFNSYMHSIKAIGESTEINDCFKSH
GISIKLSALHPRYEFSQFGRIAGEIFTKVLELCREAKKYNISLCIDAEETERLEISLILFEQLRLDESLSEWEGLGLAVQ
AYQKRALSVLDFVEDVAIRSKHKIMVRLVKGAYWDSEIKCTQELGLNDYSVFTRKSYTDVSYLVCAQKLLSKPNSFYPCF
GTHNVYTFASIMELADKNHPGFEFQRLHGMAKDLYDYAMSELATNVSCRVYAPVGEHSDLLPYLIRRLLENGANSSFVNQ
ISNPNVKIDELISDPLEKAINFNYEPHPGIPLPQDILGPERKNSLGMDISDSVIVSQFADDIKGFSEKKWQVGPIIDGKA
LFDNAEFIEVVNPAHLENVIGEVSSATSDQALNALEIAHSAFAKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAG
KILSDAIAEVREAIDFLRYYAMIAKNELSDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGGYLGKILVPDNRIAGVAFTGSTQTAQIINKMLANRDGPIVPLIAE
TGGLNAMIVDSSALLEQVTTDVLLSAFRSAGQRCSALRVLFIQEDIAEKQIKMICGAAQELKIGDPIQLSTDIGPIIDKA
SIDMLTQHTQKMSEDKDSNLLFKVPMDTNSHNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINSTGY
GLTFSLQSRIQSQIDTISKKISVGNVYINRNQIGAAVGIQPFGGRGLSGTGPKAGGPHYLQRFSTEKVVSVNTTAFGGNT
TLMCLD
>Mature_1046_residues
MISSIQEPNELRKRLQGFYRTDEKSYIRYLVEKAELSADSKNRIYNIAKQVIEKIKHNKLSIVDSFMQQYSLSNDEGIAL
MCLAESLLRIPDDYTIDELIKDKIANQEWSKYLGYSSSLFVNASMWSLMIGSSILRDNEGDSKFYYAISKLLKNLGEPII
RKAVKQAMSMLGNHFVVGETIEEALRYAKLDDNSKFLYSFDMLGEAAHTTEDAEEYFNSYMHSIKAIGESTEINDCFKSH
GISIKLSALHPRYEFSQFGRIAGEIFTKVLELCREAKKYNISLCIDAEETERLEISLILFEQLRLDESLSEWEGLGLAVQ
AYQKRALSVLDFVEDVAIRSKHKIMVRLVKGAYWDSEIKCTQELGLNDYSVFTRKSYTDVSYLVCAQKLLSKPNSFYPCF
GTHNVYTFASIMELADKNHPGFEFQRLHGMAKDLYDYAMSELATNVSCRVYAPVGEHSDLLPYLIRRLLENGANSSFVNQ
ISNPNVKIDELISDPLEKAINFNYEPHPGIPLPQDILGPERKNSLGMDISDSVIVSQFADDIKGFSEKKWQVGPIIDGKA
LFDNAEFIEVVNPAHLENVIGEVSSATSDQALNALEIAHSAFAKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAG
KILSDAIAEVREAIDFLRYYAMIAKNELSDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGGYLGKILVPDNRIAGVAFTGSTQTAQIINKMLANRDGPIVPLIAE
TGGLNAMIVDSSALLEQVTTDVLLSAFRSAGQRCSALRVLFIQEDIAEKQIKMICGAAQELKIGDPIQLSTDIGPIIDKA
SIDMLTQHTQKMSEDKDSNLLFKVPMDTNSHNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINSTGY
GLTFSLQSRIQSQIDTISKKISVGNVYINRNQIGAAVGIQPFGGRGLSGTGPKAGGPHYLQRFSTEKVVSVNTTAFGGNT
TLMCLD

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI238859541, Length=463, Percent_Identity=30.8855291576674, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI25777736, Length=463, Percent_Identity=30.8855291576674, Blast_Score=197, Evalue=6e-50,
Organism=Homo sapiens, GI25777734, Length=463, Percent_Identity=30.8855291576674, Blast_Score=197, Evalue=6e-50,
Organism=Homo sapiens, GI25777724, Length=480, Percent_Identity=29.7916666666667, Blast_Score=186, Evalue=8e-47,
Organism=Homo sapiens, GI153266822, Length=472, Percent_Identity=28.3898305084746, Blast_Score=184, Evalue=3e-46,
Organism=Homo sapiens, GI12007648, Length=483, Percent_Identity=28.5714285714286, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI21361176, Length=472, Percent_Identity=29.4491525423729, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI25777730, Length=494, Percent_Identity=29.3522267206478, Blast_Score=181, Evalue=4e-45,
Organism=Homo sapiens, GI115387104, Length=459, Percent_Identity=28.1045751633987, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI238814322, Length=485, Percent_Identity=30.1030927835052, Blast_Score=180, Evalue=5e-45,
Organism=Homo sapiens, GI21614513, Length=473, Percent_Identity=29.1754756871036, Blast_Score=179, Evalue=2e-44,
Organism=Homo sapiens, GI25777732, Length=470, Percent_Identity=28.0851063829787, Blast_Score=178, Evalue=3e-44,
Organism=Homo sapiens, GI25777728, Length=433, Percent_Identity=29.7921478060046, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI4507229, Length=497, Percent_Identity=28.5714285714286, Blast_Score=163, Evalue=7e-40,
Organism=Homo sapiens, GI25777721, Length=510, Percent_Identity=27.843137254902, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI25952152, Length=479, Percent_Identity=27.5574112734864, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI25777726, Length=480, Percent_Identity=26.875, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI188035924, Length=470, Percent_Identity=26.1702127659574, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI310128093, Length=470, Percent_Identity=26.1702127659574, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI310128103, Length=470, Percent_Identity=26.1702127659574, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI11095441, Length=429, Percent_Identity=26.8065268065268, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI310128091, Length=398, Percent_Identity=26.6331658291457, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI310128087, Length=288, Percent_Identity=28.125, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=26.7477203647416, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI4502043, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI238814371, Length=334, Percent_Identity=26.9461077844311, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI206597441, Length=434, Percent_Identity=25.8064516129032, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI206597439, Length=434, Percent_Identity=25.8064516129032, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI22907049, Length=434, Percent_Identity=25.8064516129032, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI71773324, Length=334, Percent_Identity=26.9461077844311, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI301500698, Length=289, Percent_Identity=26.643598615917, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI73695881, Length=334, Percent_Identity=25.748502994012, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI73695879, Length=334, Percent_Identity=25.748502994012, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=26.2658227848101, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4557303, Length=441, Percent_Identity=23.8095238095238, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI73466520, Length=441, Percent_Identity=23.8095238095238, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI310128097, Length=263, Percent_Identity=26.9961977186312, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128099, Length=238, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI310128101, Length=236, Percent_Identity=26.271186440678, Blast_Score=77, Evalue=7e-14,
Organism=Escherichia coli, GI1787250, Length=1035, Percent_Identity=46.280193236715, Blast_Score=934, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=476, Percent_Identity=30.4621848739496, Blast_Score=192, Evalue=8e-50,
Organism=Escherichia coli, GI1787684, Length=482, Percent_Identity=29.4605809128631, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI87081896, Length=491, Percent_Identity=28.7169042769857, Blast_Score=171, Evalue=3e-43,
Organism=Escherichia coli, GI1786504, Length=476, Percent_Identity=27.7310924369748, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI1787558, Length=476, Percent_Identity=28.3613445378151, Blast_Score=163, Evalue=4e-41,
Organism=Escherichia coli, GI1787715, Length=464, Percent_Identity=28.6637931034483, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI87082295, Length=474, Percent_Identity=28.2700421940928, Blast_Score=154, Evalue=4e-38,
Organism=Escherichia coli, GI1788042, Length=449, Percent_Identity=29.3986636971047, Blast_Score=147, Evalue=4e-36,
Organism=Escherichia coli, GI87081926, Length=424, Percent_Identity=25.9433962264151, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1787653, Length=361, Percent_Identity=24.0997229916898, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534447, Length=480, Percent_Identity=30.625, Blast_Score=195, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI25143874, Length=452, Percent_Identity=29.4247787610619, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25143876, Length=452, Percent_Identity=29.4247787610619, Blast_Score=183, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI133930964, Length=488, Percent_Identity=29.3032786885246, Blast_Score=179, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17562198, Length=489, Percent_Identity=29.4478527607362, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115532534, Length=409, Percent_Identity=30.3178484107579, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71995606, Length=462, Percent_Identity=28.1385281385281, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25144435, Length=488, Percent_Identity=28.4836065573771, Blast_Score=167, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17534119, Length=470, Percent_Identity=28.0851063829787, Blast_Score=160, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17551164, Length=485, Percent_Identity=27.4226804123711, Blast_Score=159, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI71995613, Length=412, Percent_Identity=28.1553398058252, Blast_Score=156, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=439, Percent_Identity=29.6127562642369, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32564736, Length=429, Percent_Identity=28.9044289044289, Blast_Score=152, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI32564151, Length=408, Percent_Identity=28.4313725490196, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71986308, Length=445, Percent_Identity=28.5393258426966, Blast_Score=146, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI71990744, Length=300, Percent_Identity=30, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25146391, Length=364, Percent_Identity=25.5494505494505, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=364, Percent_Identity=25.5494505494505, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=364, Percent_Identity=25.5494505494505, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=448, Percent_Identity=24.5535714285714, Blast_Score=96, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321826, Length=507, Percent_Identity=29.1913214990138, Blast_Score=191, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6320917, Length=474, Percent_Identity=31.2236286919831, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6325196, Length=469, Percent_Identity=28.997867803838, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6319478, Length=485, Percent_Identity=28.2474226804124, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6323821, Length=482, Percent_Identity=29.045643153527, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=473, Percent_Identity=28.3298097251586, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323822, Length=493, Percent_Identity=27.789046653144, Blast_Score=167, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6321828, Length=499, Percent_Identity=24.6492985971944, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=328, Percent_Identity=25, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362580, Length=494, Percent_Identity=29.5546558704453, Blast_Score=199, Evalue=1e-50,
Organism=Drosophila melanogaster, GI62472918, Length=494, Percent_Identity=29.5546558704453, Blast_Score=199, Evalue=1e-50,
Organism=Drosophila melanogaster, GI62472926, Length=494, Percent_Identity=29.5546558704453, Blast_Score=199, Evalue=1e-50,
Organism=Drosophila melanogaster, GI62472936, Length=494, Percent_Identity=29.5546558704453, Blast_Score=199, Evalue=1e-50,
Organism=Drosophila melanogaster, GI21356737, Length=494, Percent_Identity=29.5546558704453, Blast_Score=199, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24585660, Length=491, Percent_Identity=29.3279022403259, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24668425, Length=498, Percent_Identity=30.1204819277108, Blast_Score=190, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24668417, Length=498, Percent_Identity=30.1204819277108, Blast_Score=190, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24668413, Length=498, Percent_Identity=30.1204819277108, Blast_Score=190, Evalue=5e-48,
Organism=Drosophila melanogaster, GI20129399, Length=476, Percent_Identity=28.3613445378151, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI28571798, Length=491, Percent_Identity=25.050916496945, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571796, Length=491, Percent_Identity=25.050916496945, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571794, Length=491, Percent_Identity=25.050916496945, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571806, Length=491, Percent_Identity=25.050916496945, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571802, Length=491, Percent_Identity=25.050916496945, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28571800, Length=491, Percent_Identity=25.050916496945, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24650465, Length=469, Percent_Identity=27.9317697228145, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666674, Length=467, Percent_Identity=27.1948608137045, Blast_Score=144, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28574525, Length=510, Percent_Identity=25.0980392156863, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24638878, Length=442, Percent_Identity=27.8280542986425, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24638876, Length=442, Percent_Identity=27.8280542986425, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45552499, Length=449, Percent_Identity=24.2761692650334, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281360303, Length=449, Percent_Identity=24.2761692650334, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281360299, Length=449, Percent_Identity=24.2761692650334, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281360297, Length=449, Percent_Identity=24.2761692650334, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281360295, Length=449, Percent_Identity=24.2761692650334, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24586250, Length=449, Percent_Identity=24.2761692650334, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281360301, Length=449, Percent_Identity=24.2761692650334, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281360293, Length=266, Percent_Identity=24.812030075188, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 116639; Mature: 116639

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSIQEPNELRKRLQGFYRTDEKSYIRYLVEKAELSADSKNRIYNIAKQVIEKIKHNKL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHH
SIVDSFMQQYSLSNDEGIALMCLAESLLRIPDDYTIDELIKDKIANQEWSKYLGYSSSLF
HHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHCCCCCEE
VNASMWSLMIGSSILRDNEGDSKFYYAISKLLKNLGEPIIRKAVKQAMSMLGNHFVVGET
EEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEHHH
IEEALRYAKLDDNSKFLYSFDMLGEAAHTTEDAEEYFNSYMHSIKAIGESTEINDCFKSH
HHHHHHHHCCCCCCCEEEEHHHHCCHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GISIKLSALHPRYEFSQFGRIAGEIFTKVLELCREAKKYNISLCIDAEETERLEISLILF
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCEEEEEHHH
EQLRLDESLSEWEGLGLAVQAYQKRALSVLDFVEDVAIRSKHKIMVRLVKGAYWDSEIKC
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TQELGLNDYSVFTRKSYTDVSYLVCAQKLLSKPNSFYPCFGTHNVYTFASIMELADKNHP
HHHCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GFEFQRLHGMAKDLYDYAMSELATNVSCRVYAPVGEHSDLLPYLIRRLLENGANSSFVNQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHH
ISNPNVKIDELISDPLEKAINFNYEPHPGIPLPQDILGPERKNSLGMDISDSVIVSQFAD
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHH
DIKGFSEKKWQVGPIIDGKALFDNAEFIEVVNPAHLENVIGEVSSATSDQALNALEIAHS
HHCCCCCCCEEECCEECCHHHHCCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AFAKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAGKILSDAIAEVREAIDFLRYY
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIAKNELSDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
HHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEE
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGGYLGKILVPDNRIAGVAFTGSTQTA
ECCCCCCCCHHHHHHHHHHHCCCCCHHEEEECCCCCCEEEEEECCCCEEEEEEECCCHHH
QIINKMLANRDGPIVPLIAETGGLNAMIVDSSALLEQVTTDVLLSAFRSAGQRCSALRVL
HHHHHHHCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FIQEDIAEKQIKMICGAAQELKIGDPIQLSTDIGPIIDKASIDMLTQHTQKMSEDKDSNL
HHHHHHHHHHHHHHHCCHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
LFKVPMDTNSHNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINSTGY
EEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
GLTFSLQSRIQSQIDTISKKISVGNVYINRNQIGAAVGIQPFGGRGLSGTGPKAGGPHYL
CEEEHHHHHHHHHHHHHHHHEEECEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCHHHH
QRFSTEKVVSVNTTAFGGNTTLMCLD
HHCCCCCEEEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MISSIQEPNELRKRLQGFYRTDEKSYIRYLVEKAELSADSKNRIYNIAKQVIEKIKHNKL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHH
SIVDSFMQQYSLSNDEGIALMCLAESLLRIPDDYTIDELIKDKIANQEWSKYLGYSSSLF
HHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHCCCCCEE
VNASMWSLMIGSSILRDNEGDSKFYYAISKLLKNLGEPIIRKAVKQAMSMLGNHFVVGET
EEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEHHH
IEEALRYAKLDDNSKFLYSFDMLGEAAHTTEDAEEYFNSYMHSIKAIGESTEINDCFKSH
HHHHHHHHCCCCCCCEEEEHHHHCCHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GISIKLSALHPRYEFSQFGRIAGEIFTKVLELCREAKKYNISLCIDAEETERLEISLILF
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCEEEEEHHH
EQLRLDESLSEWEGLGLAVQAYQKRALSVLDFVEDVAIRSKHKIMVRLVKGAYWDSEIKC
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TQELGLNDYSVFTRKSYTDVSYLVCAQKLLSKPNSFYPCFGTHNVYTFASIMELADKNHP
HHHCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GFEFQRLHGMAKDLYDYAMSELATNVSCRVYAPVGEHSDLLPYLIRRLLENGANSSFVNQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHH
ISNPNVKIDELISDPLEKAINFNYEPHPGIPLPQDILGPERKNSLGMDISDSVIVSQFAD
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHH
DIKGFSEKKWQVGPIIDGKALFDNAEFIEVVNPAHLENVIGEVSSATSDQALNALEIAHS
HHCCCCCCCEEECCEECCHHHHCCCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AFAKWQNVSAEERAKCLEKAADLLEERMKELIYILIVEAGKILSDAIAEVREAIDFLRYY
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIAKNELSDWKKLPGPTGEDNFIFFEGRGVFLCISPWNFPLAIFIGQVSAALAAGNAVL
HHHHHHHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEE
AKPAEQTPIIAYEAVKILHEAGIPKNVLHLIPGDGGYLGKILVPDNRIAGVAFTGSTQTA
ECCCCCCCCHHHHHHHHHHHCCCCCHHEEEECCCCCCEEEEEECCCCEEEEEEECCCHHH
QIINKMLANRDGPIVPLIAETGGLNAMIVDSSALLEQVTTDVLLSAFRSAGQRCSALRVL
HHHHHHHCCCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FIQEDIAEKQIKMICGAAQELKIGDPIQLSTDIGPIIDKASIDMLTQHTQKMSEDKDSNL
HHHHHHHHHHHHHHHCCHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
LFKVPMDTNSHNGYFFPPYIYEIQKISQLKQEVFGPILHIIRFNKSQLNEVISDINSTGY
EEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
GLTFSLQSRIQSQIDTISKKISVGNVYINRNQIGAAVGIQPFGGRGLSGTGPKAGGPHYL
CEEEHHHHHHHHHHHHHHHHEEECEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCHHHH
QRFSTEKVVSVNTTAFGGNTTLMCLD
HHCCCCCEEEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]