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The map label for this gene is dnaQ [H]

Identifier: 225629990

GI number: 225629990

Start: 143654

End: 144349

Strand: Reverse

Name: dnaQ [H]

Synonym: WRi_001440

Alternate gene names: 225629990

Gene position: 144349-143654 (Counterclockwise)

Preceding gene: 225629991

Following gene: 225629989

Centisome position: 9.98

GC content: 35.63

Gene sequence:

>696_bases
ATGGAAAGCAAGCTACGCGAACTAGTACTTGACACTGAAACGACAGGTCTTGACACTGAATCTGGTCATCGAATTATTGA
AATAGGGTGTGTGGAATTAATTAATCGTATTCCAACAGGTAAAGTATTCCATCGGTACCTTAACCCAGAAAGAGATATAC
CTTATCACTCGTTTAAGATTCACGGTATTAGTGAAGAATTTTTAGAAGATAAACCATTATTTTCAGATGTTGCACTTGAA
TTTCTTGACTTTATATCTAATGATATTTTGGTAATTCACAACGCTGAATTCGATGTTAAGTTCCTTAACATGGAGCTAAG
CAAGCTGAATGCTGGGTTAATTTCCTCAGATAGAGTGCTAGATACATTACCTCTTGCGAGGAAAAAATTCGCAGGATCAC
CTGCTTCTTTGAATGCATTATGTAAGCGTTTTGATATATCGCTAGAGAATAGAGAATTGCACGGAGCACTAGTTGATGCT
CAATTGCTTGCAAAGGTATATGTTGAACTTACAGGAGGGTTACAAACCTTTCTGTTTGATAATGAATGCAATCAGGACAG
TAACTCTACATTCGTTCAGCATAAAGTGCGTAATCTAACTCCCAGAGAACATTCACCAAATAGTGAAGAAATTGATGAAC
ATAAGAAACTGTTAGACAAAATTAACAATACACTTTGGAATAAATATATTGAATAG

Upstream 100 bases:

>100_bases
TTCATCAGACCCAAGCTGGTTGCTTGTTTCTATTCACTATAAAAAGACAAGTAACGATAAGACAAATGACAAGTAAGATT
AGTTTTATTTAGAGTTAACC

Downstream 100 bases:

>100_bases
GTCAACTAATAAAGATACAATTTAATTTTACTGAGAGCACCCTAATGGTAAGGTTTATAAGATTGTTATCTAATGTGCTA
GCAGCATTAGCAGTTGTTTT

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MESKLRELVLDTETTGLDTESGHRIIEIGCVELINRIPTGKVFHRYLNPERDIPYHSFKIHGISEEFLEDKPLFSDVALE
FLDFISNDILVIHNAEFDVKFLNMELSKLNAGLISSDRVLDTLPLARKKFAGSPASLNALCKRFDISLENRELHGALVDA
QLLAKVYVELTGGLQTFLFDNECNQDSNSTFVQHKVRNLTPREHSPNSEEIDEHKKLLDKINNTLWNKYIE

Sequences:

>Translated_231_residues
MESKLRELVLDTETTGLDTESGHRIIEIGCVELINRIPTGKVFHRYLNPERDIPYHSFKIHGISEEFLEDKPLFSDVALE
FLDFISNDILVIHNAEFDVKFLNMELSKLNAGLISSDRVLDTLPLARKKFAGSPASLNALCKRFDISLENRELHGALVDA
QLLAKVYVELTGGLQTFLFDNECNQDSNSTFVQHKVRNLTPREHSPNSEEIDEHKKLLDKINNTLWNKYIE
>Mature_231_residues
MESKLRELVLDTETTGLDTESGHRIIEIGCVELINRIPTGKVFHRYLNPERDIPYHSFKIHGISEEFLEDKPLFSDVALE
FLDFISNDILVIHNAEFDVKFLNMELSKLNAGLISSDRVLDTLPLARKKFAGSPASLNALCKRFDISLENRELHGALVDA
QLLAKVYVELTGGLQTFLFDNECNQDSNSTFVQHKVRNLTPREHSPNSEEIDEHKKLLDKINNTLWNKYIE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=235, Percent_Identity=44.2553191489362, Blast_Score=187, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26422; Mature: 26422

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESKLRELVLDTETTGLDTESGHRIIEIGCVELINRIPTGKVFHRYLNPERDIPYHSFKI
CCHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEE
HGISEEFLEDKPLFSDVALEFLDFISNDILVIHNAEFDVKFLNMELSKLNAGLISSDRVL
ECCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEHHHHCCCCCCCCCHH
DTLPLARKKFAGSPASLNALCKRFDISLENRELHGALVDAQLLAKVYVELTGGLQTFLFD
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
NECNQDSNSTFVQHKVRNLTPREHSPNSEEIDEHKKLLDKINNTLWNKYIE
CCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MESKLRELVLDTETTGLDTESGHRIIEIGCVELINRIPTGKVFHRYLNPERDIPYHSFKI
CCHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEE
HGISEEFLEDKPLFSDVALEFLDFISNDILVIHNAEFDVKFLNMELSKLNAGLISSDRVL
ECCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEHHHHCCCCCCCCCHH
DTLPLARKKFAGSPASLNALCKRFDISLENRELHGALVDAQLLAKVYVELTGGLQTFLFD
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
NECNQDSNSTFVQHKVRNLTPREHSPNSEEIDEHKKLLDKINNTLWNKYIE
CCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]