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The map label for this gene is coxC [H]

Identifier: 225629966

GI number: 225629966

Start: 115088

End: 115915

Strand: Reverse

Name: coxC [H]

Synonym: WRi_001120

Alternate gene names: 225629966

Gene position: 115915-115088 (Counterclockwise)

Preceding gene: 225629967

Following gene: 225629965

Centisome position: 8.02

GC content: 35.63

Gene sequence:

>828_bases
ATGAAAAGTAAAGAACATGATTTTCATTTAGTGGATCCAAGCCCTTGGCCAATTGCTGTATCAGCAGCAATTCTTATTCT
TGCACTTGGATTAGTTGGCGCGCTTCATAAACAAATTGTCGGAATGTTTTGTTTAGTTTTGGGAATCTCCGCAGTATCAG
GGGTGCTGTTTTATTGGTGGAGAGATGTAATAAGGGAGGCCATTTATGACAAATGTCACACTGCCATTGTAAAACATGGA
CTCAAATTTGCAATGTACTTGTTTATTCTCTCGGAGGTCGTATTTTTTATAGTGTTCTTTTGTTCATTCTTTAAAGCCTG
GCTTGATCCAGTTTTTTTATTTGAGGCGTTTTCTCCTGCAAAAAAAGTTGAATGGCCCCCTGAGGGAATTTTGCCACCTG
ATCCGTGGTCACTACCATTCATGAATACATTAATATTATTGCTTTCTGGTACAACAATTACTTGGGCAAATCACTCTTTA
CTTAAAAATGATAAAAAGAGCATGATTAAAATGCTGTCCATAACTATATTGCTTGGAGTGTTTTTTATAATAGTGCAAGC
AATAGAGTATCATGAAGCGAGTTTTTCTCTACAAGAAACAGGAGAAAAGCTTATTTATACATCCAATTTTTATATGATTA
CCGGTTTTCACTGCGCACACGTTATAATAGGAATAATATTTTTATCAGTGTGTTTATTTAGAGCACGGAAAGGCCAATTT
ACACTTCAGGACCATTTGTGCTTTGAGTTTGCCTCCTGGTATTGGCACTTTGTAGATGTAGTCTGGATATTTTTATTTTT
GTTTGTCTATTGGTTAAGCGTTTATTAA

Upstream 100 bases:

>100_bases
TGAACGGTGCATATAATTTTTCAAGATTCAATCAATTTCCTAAGGAACATTGACAATTTTAAGCTAATTTGTATCCTTAA
TAAGTATTTTTTAAAATGCT

Downstream 100 bases:

>100_bases
GTGGTTAAAATAATAGGTCTAGATCCAGGAATAAGCAAGACTGGGTGGGCCATTATCAGCCTGAACGAAAAAAATAATAT
TGAATTTTTGGGCGGCGGTA

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKSKEHDFHLVDPSPWPIAVSAAILILALGLVGALHKQIVGMFCLVLGISAVSGVLFYWWRDVIREAIYDKCHTAIVKHG
LKFAMYLFILSEVVFFIVFFCSFFKAWLDPVFLFEAFSPAKKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITWANHSL
LKNDKKSMIKMLSITILLGVFFIIVQAIEYHEASFSLQETGEKLIYTSNFYMITGFHCAHVIIGIIFLSVCLFRARKGQF
TLQDHLCFEFASWYWHFVDVVWIFLFLFVYWLSVY

Sequences:

>Translated_275_residues
MKSKEHDFHLVDPSPWPIAVSAAILILALGLVGALHKQIVGMFCLVLGISAVSGVLFYWWRDVIREAIYDKCHTAIVKHG
LKFAMYLFILSEVVFFIVFFCSFFKAWLDPVFLFEAFSPAKKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITWANHSL
LKNDKKSMIKMLSITILLGVFFIIVQAIEYHEASFSLQETGEKLIYTSNFYMITGFHCAHVIIGIIFLSVCLFRARKGQF
TLQDHLCFEFASWYWHFVDVVWIFLFLFVYWLSVY
>Mature_275_residues
MKSKEHDFHLVDPSPWPIAVSAAILILALGLVGALHKQIVGMFCLVLGISAVSGVLFYWWRDVIREAIYDKCHTAIVKHG
LKFAMYLFILSEVVFFIVFFCSFFKAWLDPVFLFEAFSPAKKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITWANHSL
LKNDKKSMIKMLSITILLGVFFIIVQAIEYHEASFSLQETGEKLIYTSNFYMITGFHCAHVIIGIIFLSVCLFRARKGQF
TLQDHLCFEFASWYWHFVDVVWIFLFLFVYWLSVY

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=271, Percent_Identity=44.280442804428, Blast_Score=218, Evalue=4e-57,
Organism=Escherichia coli, GI1786633, Length=194, Percent_Identity=26.8041237113402, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6226542, Length=273, Percent_Identity=35.5311355311355, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31774; Mature: 31774

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKEHDFHLVDPSPWPIAVSAAILILALGLVGALHKQIVGMFCLVLGISAVSGVLFYWW
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVIREAIYDKCHTAIVKHGLKFAMYLFILSEVVFFIVFFCSFFKAWLDPVFLFEAFSPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITWANHSLLKNDKKSMIKMLSITILLGV
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
FFIIVQAIEYHEASFSLQETGEKLIYTSNFYMITGFHCAHVIIGIIFLSVCLFRARKGQF
HHHHHHHHHHHHHCCCHHHCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
TLQDHLCFEFASWYWHFVDVVWIFLFLFVYWLSVY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSKEHDFHLVDPSPWPIAVSAAILILALGLVGALHKQIVGMFCLVLGISAVSGVLFYWW
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDVIREAIYDKCHTAIVKHGLKFAMYLFILSEVVFFIVFFCSFFKAWLDPVFLFEAFSPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITWANHSLLKNDKKSMIKMLSITILLGV
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
FFIIVQAIEYHEASFSLQETGEKLIYTSNFYMITGFHCAHVIIGIIFLSVCLFRARKGQF
HHHHHHHHHHHHHCCCHHHCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCC
TLQDHLCFEFASWYWHFVDVVWIFLFLFVYWLSVY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA