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The map label for this gene is nuoG [H]

Identifier: 225629947

GI number: 225629947

Start: 90511

End: 92580

Strand: Direct

Name: nuoG [H]

Synonym: WRi_000920

Alternate gene names: 225629947

Gene position: 90511-92580 (Clockwise)

Preceding gene: 225629946

Following gene: 225629948

Centisome position: 6.26

GC content: 38.65

Gene sequence:

>2070_bases
GTGGGAAGCTGTATAATAGTTGTGGTTAAAGTTACTATTAATTCTAAGGAATGTGAAGTAGAGCATGGGCTCACTATAAT
TCAAGCTTGTGAAGTCGTGGGCGTTGAAATTCCACGTTTTTGTTATCATGAGCGTTTAGCAATTGCTGGTAATTGCAGAA
TGTGTTTGGTTGAAGTGGAGGGTGGACCTCCAAAACCAGTAGCCTCTTGTGCAATGCCAGTTGCAGAAGGGATGGTTATT
CACACTGATACCCCTAAGGTTAAAAAAGCACGTGAAGGTGTGCTTGAGTTTTTGCTAATTAACCACCCGCTTGATTGCCC
AATTTGCGATCAAGGTGGTGAATGCGATTTGCAAGATATCACGATGGCTTATGGGAAAGGAACCAGCAGACTTGATGAGC
ATAAGAGGGCTGTGCCAAAAAAACACTTCGGACCACTGATTGAGACTGCGATGAATCGATGCATTCATTGCACTCGGTGT
GTTAGATTTTTGTCTGATGTTGCAGGTACAAATGAACTTGGAGGAATCGGAAGGGGAGAAAATGTAGAGATTAGCACTTA
CATAAAAAGGCATATTAGTTCTGAATTATCTGGAAATATCATAGATCTCTGCCCGGTAGGGGCTTTAACTTCAAAGCCTT
ACTCCTTTACAGCGCGTCCATGGGAGCTATCACATTGTGAGACTATAGATGTGCTAGATGCTGTGGGTAGCGCAATTAGA
GTTGATTATCGTGGCCCGGAGGTTATGAGGATATTACCAAGGCTGAGCGAAGAGGTAAATGAAGAATGGATATCAGATAA
AACCCGCTTTGCCTATGATGGACTAAAAGTTCAGCGTCTTGATCAACCTTATATAAAAAAAGATGGTAAATTAGCCCCAG
TTGATTGGAATGAGGCATTAACTGTTGCTGCAAAGAAATTAAAGAATACAAAATCAAATAAAATAGCTGCAATTGCAGGT
GATTTAGCAGATTGTGAGTCTATGCTTCTACTTAAAGAAATGATGCAGAAGCTCGGCTCGGGGAATATAGACTGTAGGCA
AGATGGTGCAAAGCTTATACCAAGTAATCGTGGATCGTATGTGTTCAATACCACTATTGAAGGTATAGAAAATGCAGATT
TATGTCTGCTTATAAATACAAATCCAAGGATAGAAGCACCGATCATTAACGTAAGATTGAGAAAGAGATATTTACAGGGC
AACTTTCCTGTTGCAAGTGTTGGTCCTAACATTGAATATTTGTATCATGTTGAGAAATTGGGCGATAATCCTGATATTTT
GAGTGAAATAGCAAATGGAAATCATAAGTTCTGTGAGCTGCTGGTAGCTGCTCAAAACCCTATGCTGATTATCGGTCAAG
ATGCGTTGATAAGAGATGATTCTGAATCAGTTCTAATTCTAGCTGGCAAAATTGCAGAAAAATTTAACATGGTCAGAGAT
GACTGGAATGGCTTTAATGTGCTGCATAAAGCTGCAGCAAGAGTTGGTGGGCTAGATATTGGGTTTGTTCCTGAAAAAGG
CGAAAGGGATATTAATCAAATATTGGAACATGCAGAAAGTGGTGAAACAGAAGTGGTTTATCTTCTTGGTGCAGATGAAA
TTGATACATCAAAATTAGAAAATACATTTGTAATTTATCAAGGTCATCACGGTGATAAGGGTGCACATGTGGCAGATGTT
ATCTTGCCTGGTGCTGCATATACAGAAAAATATGCAACTTATGTAAACACTGAAGGTCGAGTGCAAAGAACAAATTTAGC
TGTATTTCCTCCAGGTGAAGCAAAGGAGGATTGGTTAATTATTAAAAATCTCTCGCAATATTTGGATCTCTCCTTACCAT
ATGATAGTTTATTTGACGTGAGAAAAAAATTAGATACTATCGGTCCACAGTTTAGAAATGCTGATCAAGTGATAAAAAAC
ACATGGGTGCCAATTAGCAATGGTAAAATAAATTTAAGTGATACACCTTTTACTTTAAAGGAGTGTAATTTTTATATGAC
GGATTCAATAAGTCGCGCTTCAAAAATAATGGCGGATTGTACTAAAGCTTTTTATGAACACGCTAGTTAA

Upstream 100 bases:

>100_bases
CTGTTAGATATATAGATCGTGATTCGCGCATGAATTATATGTCTGCTCAATATGACAACGGCAATCTGGTTGAAGATGAG
GTAAGCGGCAATCCTATAAA

Downstream 100 bases:

>100_bases
TATTTTATTTATTTTAGTACCGCTACTACTTTCAGTTGCATATTTGACATACTTTGAGCGTAAGGTCCTTGCTGCAATTC
AACTAAGGCACGGCCCGAGT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 689; Mature: 688

Protein sequence:

>689_residues
MGSCIIVVVKVTINSKECEVEHGLTIIQACEVVGVEIPRFCYHERLAIAGNCRMCLVEVEGGPPKPVASCAMPVAEGMVI
HTDTPKVKKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKGTSRLDEHKRAVPKKHFGPLIETAMNRCIHCTRC
VRFLSDVAGTNELGGIGRGENVEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSAIR
VDYRGPEVMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYIKKDGKLAPVDWNEALTVAAKKLKNTKSNKIAAIAG
DLADCESMLLLKEMMQKLGSGNIDCRQDGAKLIPSNRGSYVFNTTIEGIENADLCLLINTNPRIEAPIINVRLRKRYLQG
NFPVASVGPNIEYLYHVEKLGDNPDILSEIANGNHKFCELLVAAQNPMLIIGQDALIRDDSESVLILAGKIAEKFNMVRD
DWNGFNVLHKAAARVGGLDIGFVPEKGERDINQILEHAESGETEVVYLLGADEIDTSKLENTFVIYQGHHGDKGAHVADV
ILPGAAYTEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQYLDLSLPYDSLFDVRKKLDTIGPQFRNADQVIKN
TWVPISNGKINLSDTPFTLKECNFYMTDSISRASKIMADCTKAFYEHAS

Sequences:

>Translated_689_residues
MGSCIIVVVKVTINSKECEVEHGLTIIQACEVVGVEIPRFCYHERLAIAGNCRMCLVEVEGGPPKPVASCAMPVAEGMVI
HTDTPKVKKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKGTSRLDEHKRAVPKKHFGPLIETAMNRCIHCTRC
VRFLSDVAGTNELGGIGRGENVEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSAIR
VDYRGPEVMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYIKKDGKLAPVDWNEALTVAAKKLKNTKSNKIAAIAG
DLADCESMLLLKEMMQKLGSGNIDCRQDGAKLIPSNRGSYVFNTTIEGIENADLCLLINTNPRIEAPIINVRLRKRYLQG
NFPVASVGPNIEYLYHVEKLGDNPDILSEIANGNHKFCELLVAAQNPMLIIGQDALIRDDSESVLILAGKIAEKFNMVRD
DWNGFNVLHKAAARVGGLDIGFVPEKGERDINQILEHAESGETEVVYLLGADEIDTSKLENTFVIYQGHHGDKGAHVADV
ILPGAAYTEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQYLDLSLPYDSLFDVRKKLDTIGPQFRNADQVIKN
TWVPISNGKINLSDTPFTLKECNFYMTDSISRASKIMADCTKAFYEHAS
>Mature_688_residues
GSCIIVVVKVTINSKECEVEHGLTIIQACEVVGVEIPRFCYHERLAIAGNCRMCLVEVEGGPPKPVASCAMPVAEGMVIH
TDTPKVKKAREGVLEFLLINHPLDCPICDQGGECDLQDITMAYGKGTSRLDEHKRAVPKKHFGPLIETAMNRCIHCTRCV
RFLSDVAGTNELGGIGRGENVEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSAIRV
DYRGPEVMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYIKKDGKLAPVDWNEALTVAAKKLKNTKSNKIAAIAGD
LADCESMLLLKEMMQKLGSGNIDCRQDGAKLIPSNRGSYVFNTTIEGIENADLCLLINTNPRIEAPIINVRLRKRYLQGN
FPVASVGPNIEYLYHVEKLGDNPDILSEIANGNHKFCELLVAAQNPMLIIGQDALIRDDSESVLILAGKIAEKFNMVRDD
WNGFNVLHKAAARVGGLDIGFVPEKGERDINQILEHAESGETEVVYLLGADEIDTSKLENTFVIYQGHHGDKGAHVADVI
LPGAAYTEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLIIKNLSQYLDLSLPYDSLFDVRKKLDTIGPQFRNADQVIKNT
WVPISNGKINLSDTPFTLKECNFYMTDSISRASKIMADCTKAFYEHAS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=702, Percent_Identity=50.2849002849003, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=675, Percent_Identity=25.6296296296296, Blast_Score=202, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17565758, Length=701, Percent_Identity=46.5049928673324, Blast_Score=629, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI32566231, Length=589, Percent_Identity=49.2359932088285, Blast_Score=573, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=59.1269841269841, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24640559, Length=696, Percent_Identity=47.4137931034483, Blast_Score=634, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=696, Percent_Identity=47.4137931034483, Blast_Score=634, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 76251; Mature: 76120

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSCIIVVVKVTINSKECEVEHGLTIIQACEVVGVEIPRFCYHERLAIAGNCRMCLVEVE
CCCEEEEEEEEEECCCCCCHHHCCHHHHHHHHHCCCCCHHHHHCCEEEECCCEEEEEEEC
GGPPKPVASCAMPVAEGMVIHTDTPKVKKAREGVLEFLLINHPLDCPICDQGGECDLQDI
CCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TMAYGKGTSRLDEHKRAVPKKHFGPLIETAMNRCIHCTRCVRFLSDVAGTNELGGIGRGE
HHHHCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NVEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSAIR
CEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCEEE
VDYRGPEVMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYIKKDGKLAPVDWNEAL
EECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCHHCCCCCCCCCCCCHHH
TVAAKKLKNTKSNKIAAIAGDLADCESMLLLKEMMQKLGSGNIDCRQDGAKLIPSNRGSY
HHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCE
VFNTTIEGIENADLCLLINTNPRIEAPIINVRLRKRYLQGNFPVASVGPNIEYLYHVEKL
EEEEEECCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCEEEEEEECC
GDNPDILSEIANGNHKFCELLVAAQNPMLIIGQDALIRDDSESVLILAGKIAEKFNMVRD
CCCHHHHHHHHCCCHHHHHEEEECCCCEEEEECCCEEECCCCCEEEEEHHHHHHHHHHHC
DWNGFNVLHKAAARVGGLDIGFVPEKGERDINQILEHAESGETEVVYLLGADEIDTSKLE
CCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
NTFVIYQGHHGDKGAHVADVILPGAAYTEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLI
CEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHEECCCCCEEECEEEEECCCCCCCCEEE
IKNLSQYLDLSLPYDSLFDVRKKLDTIGPQFRNADQVIKNTWVPISNGKINLSDTPFTLK
HCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEECCCEEEECCCCEEHH
ECNFYMTDSISRASKIMADCTKAFYEHAS
HCCEEECCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSCIIVVVKVTINSKECEVEHGLTIIQACEVVGVEIPRFCYHERLAIAGNCRMCLVEVE
CCEEEEEEEEEECCCCCCHHHCCHHHHHHHHHCCCCCHHHHHCCEEEECCCEEEEEEEC
GGPPKPVASCAMPVAEGMVIHTDTPKVKKAREGVLEFLLINHPLDCPICDQGGECDLQDI
CCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH
TMAYGKGTSRLDEHKRAVPKKHFGPLIETAMNRCIHCTRCVRFLSDVAGTNELGGIGRGE
HHHHCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NVEISTYIKRHISSELSGNIIDLCPVGALTSKPYSFTARPWELSHCETIDVLDAVGSAIR
CEEHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCEEE
VDYRGPEVMRILPRLSEEVNEEWISDKTRFAYDGLKVQRLDQPYIKKDGKLAPVDWNEAL
EECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCCHHCCCCCCCCCCCCHHH
TVAAKKLKNTKSNKIAAIAGDLADCESMLLLKEMMQKLGSGNIDCRQDGAKLIPSNRGSY
HHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCE
VFNTTIEGIENADLCLLINTNPRIEAPIINVRLRKRYLQGNFPVASVGPNIEYLYHVEKL
EEEEEECCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHCCCCCEEECCCCCEEEEEEECC
GDNPDILSEIANGNHKFCELLVAAQNPMLIIGQDALIRDDSESVLILAGKIAEKFNMVRD
CCCHHHHHHHHCCCHHHHHEEEECCCCEEEEECCCEEECCCCCEEEEEHHHHHHHHHHHC
DWNGFNVLHKAAARVGGLDIGFVPEKGERDINQILEHAESGETEVVYLLGADEIDTSKLE
CCCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
NTFVIYQGHHGDKGAHVADVILPGAAYTEKYATYVNTEGRVQRTNLAVFPPGEAKEDWLI
CEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHEECCCCCEEECEEEEECCCCCCCCEEE
IKNLSQYLDLSLPYDSLFDVRKKLDTIGPQFRNADQVIKNTWVPISNGKINLSDTPFTLK
HCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCEEECCCEEEECCCCEEHH
ECNFYMTDSISRASKIMADCTKAFYEHAS
HCCEEECCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA