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The map label for this gene is nuoH [H]

Identifier: 225629948

GI number: 225629948

Start: 92564

End: 93589

Strand: Direct

Name: nuoH [H]

Synonym: WRi_000930

Alternate gene names: 225629948

Gene position: 92564-93589 (Clockwise)

Preceding gene: 225629947

Following gene: 225629949

Centisome position: 6.4

GC content: 38.11

Gene sequence:

>1026_bases
ATGAACACGCTAGTTAATATTTTATTTATTTTAGTACCGCTACTACTTTCAGTTGCATATTTGACATACTTTGAGCGTAA
GGTCCTTGCTGCAATTCAACTAAGGCACGGCCCGAGTGTAGTTGGACCTTTTGGGCTATTGCAGCCATTTGCAGATGCTA
TTAAGCTACTGATTAAAGAGCCGATAATACCATTTAGAGCGAGCACCATACTGTTCATTATGGCTCCAATGCTTACCTTT
ATCTTGGCATTAATTGCCTGGGCAGTTATACCGTTTGGTGCTGAAGTAATTGTAGAAAATGGCCAGCAAGTAGTTATTCC
TAAGGTTATAGCAAATATTAATGTTGGAGTGCTTTATGTGCTAGCTATATCGTCGCTGGGAGTATACGGCGTGATTATTG
CAGGCTGGTCAAGCAATTCTAATTATGCATTTCTTGGTGCTATACGGTCGGCTGCTCAGATGATTTCGTATGAAGTTTCA
ATAGGCTTAATAGTTGCTACAGTCGTTATTACCACTGGAACATTAAATCTTGGAGAGATGGTGGTAGCGAAACACAATAT
GCCATTTTGGGTTGATTTACTACTAATGCCTATAGGAATAATATTTTTTATTTCTTTGCTTGCAGAAACTAATCGTCACC
CGTTTGATTTACCAGAAGCTGAAGCAGAGCTTGTCTCTGGATATAACGTTGAATATTCATCCATGCCTTTTGCCCTCTTT
TTTCTTGGAGAATATGCAAATATGATTCTAGCAAGTGCTATGATGACGATATTCTTTCTAGGAGGATGGTATCCTCCGTT
AGAACTTGGTTTGCTTTATAAAATTCCAGGTTTAATTTGGTTCGTTTTGAAGATAATTATACTTTTATTCGTATTTATTT
GGATTAGAGCAACAATACCTCGTTATCGATATGATCAGCTAATGCGCCTTGGTTGGAAAGTATTTCTACCAATATCAGTG
TTTTGGGTGATACTCATTTCAGGGGTGTTGCTCTTTACTGGGAATTTGCCTGGATCCAATGTTTAA

Upstream 100 bases:

>100_bases
TTAAGTGATACACCTTTTACTTTAAAGGAGTGTAATTTTTATATGACGGATTCAATAAGTCGCGCTTCAAAAATAATGGC
GGATTGTACTAAAGCTTTTT

Downstream 100 bases:

>100_bases
TTTCCCAAATACAAGATTAAGACGCAGGCGCTCGAGCAAATGGGTTCGCAATTTAACAAGTGAAAATAGTTTATCAGTAA
ATGATCTGGTTCTTCCTCTG

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNTLVNILFILVPLLLSVAYLTYFERKVLAAIQLRHGPSVVGPFGLLQPFADAIKLLIKEPIIPFRASTILFIMAPMLTF
ILALIAWAVIPFGAEVIVENGQQVVIPKVIANINVGVLYVLAISSLGVYGVIIAGWSSNSNYAFLGAIRSAAQMISYEVS
IGLIVATVVITTGTLNLGEMVVAKHNMPFWVDLLLMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
FLGEYANMILASAMMTIFFLGGWYPPLELGLLYKIPGLIWFVLKIIILLFVFIWIRATIPRYRYDQLMRLGWKVFLPISV
FWVILISGVLLFTGNLPGSNV

Sequences:

>Translated_341_residues
MNTLVNILFILVPLLLSVAYLTYFERKVLAAIQLRHGPSVVGPFGLLQPFADAIKLLIKEPIIPFRASTILFIMAPMLTF
ILALIAWAVIPFGAEVIVENGQQVVIPKVIANINVGVLYVLAISSLGVYGVIIAGWSSNSNYAFLGAIRSAAQMISYEVS
IGLIVATVVITTGTLNLGEMVVAKHNMPFWVDLLLMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
FLGEYANMILASAMMTIFFLGGWYPPLELGLLYKIPGLIWFVLKIIILLFVFIWIRATIPRYRYDQLMRLGWKVFLPISV
FWVILISGVLLFTGNLPGSNV
>Mature_341_residues
MNTLVNILFILVPLLLSVAYLTYFERKVLAAIQLRHGPSVVGPFGLLQPFADAIKLLIKEPIIPFRASTILFIMAPMLTF
ILALIAWAVIPFGAEVIVENGQQVVIPKVIANINVGVLYVLAISSLGVYGVIIAGWSSNSNYAFLGAIRSAAQMISYEVS
IGLIVATVVITTGTLNLGEMVVAKHNMPFWVDLLLMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
FLGEYANMILASAMMTIFFLGGWYPPLELGLLYKIPGLIWFVLKIIILLFVFIWIRATIPRYRYDQLMRLGWKVFLPISV
FWVILISGVLLFTGNLPGSNV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=304, Percent_Identity=45.0657894736842, Blast_Score=264, Evalue=1e-70,
Organism=Escherichia coli, GI1788618, Length=335, Percent_Identity=39.7014925373134, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 37822; Mature: 37822

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLVNILFILVPLLLSVAYLTYFERKVLAAIQLRHGPSVVGPFGLLQPFADAIKLLIKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PIIPFRASTILFIMAPMLTFILALIAWAVIPFGAEVIVENGQQVVIPKVIANINVGVLYV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCEEEEHHHHHCCCHHHHHH
LAISSLGVYGVIIAGWSSNSNYAFLGAIRSAAQMISYEVSIGLIVATVVITTGTLNLGEM
HHHHHCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
VVAKHNMPFWVDLLLMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEECCCCHHHH
FLGEYANMILASAMMTIFFLGGWYPPLELGLLYKIPGLIWFVLKIIILLFVFIWIRATIP
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RYRYDQLMRLGWKVFLPISVFWVILISGVLLFTGNLPGSNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MNTLVNILFILVPLLLSVAYLTYFERKVLAAIQLRHGPSVVGPFGLLQPFADAIKLLIKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PIIPFRASTILFIMAPMLTFILALIAWAVIPFGAEVIVENGQQVVIPKVIANINVGVLYV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCEEEEHHHHHCCCHHHHHH
LAISSLGVYGVIIAGWSSNSNYAFLGAIRSAAQMISYEVSIGLIVATVVITTGTLNLGEM
HHHHHCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
VVAKHNMPFWVDLLLMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEECCCCHHHH
FLGEYANMILASAMMTIFFLGGWYPPLELGLLYKIPGLIWFVLKIIILLFVFIWIRATIP
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RYRYDQLMRLGWKVFLPISVFWVILISGVLLFTGNLPGSNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA