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The map label for this gene is ybiK [C]

Identifier: 222527008

GI number: 222527008

Start: 4717865

End: 4718764

Strand: Reverse

Name: ybiK [C]

Synonym: Chy400_3787

Alternate gene names: 222527008

Gene position: 4718764-4717865 (Counterclockwise)

Preceding gene: 222527011

Following gene: 222527007

Centisome position: 89.56

GC content: 61.33

Gene sequence:

>900_bases
ATGACAGCAGAACCAGTGCAGGCACTTATCGTCCACGGTGGGGCGTGGGCCATTCCCGATGATCAGGTCACCGCTCATAT
TGCCGGTTGCATCGCAGCGCGGACTGCCGGATGGCAGGTGTTGCAGAACGGTGGTAGTGCGCTTGATGCGGTGGAGGCGG
CGGTGCGGGTGATGGAAGACGATCCGATCTTTGACGCCGGCACCGGATCGGTGCTGACCAGTGCCGGCACTGTTGAATTG
GACGCGGCATTGATGGATGGTCGCACGCTGCGTTACGGTGCAGTTGCCGGTCTCCAGCGCATTCGCAATCCAATCACACT
CGCCCGCCACGTATTGAACGGGCCGGCGACGATGCTGGTTGGCCCCGGTGCTGAAGCATTTGCGGCGACAGTGGGTATAC
CTTTCTGCGATAATGCAGAGTTAGTCGTAGAACGTGAACGCCAGTTGTGGCTGGCCTGGAAAGCACAGGGATCGCCACCA
CCACCACCGGCCAGCGGTCACGACACCGTCGGGGCGATTGCCCTTGATCAGTCCGGCCAGCTTGTGGCTGCCAATTCAAC
CGGTGGCACACCTTTCAAATTGCCTGGCCGGGTCGGTGATACGCCGCTCATTGGTTGTGGTCTCTACGCCACTGCAGATG
GGGCAGCGGTATGTACCGGTTGGGGCGAGTCTATTACTCGTGTGGCATTGGCCCGACGGGTCGTCGAATTGCTTGAAGAC
GGTATGCACCCCCAGGAGGCTGCCGAACGCGGGATCAAACTGTTGTCTGAACTGGTGCCAGATGGACGTGGCGGCGTGAT
TGTCCTGACACCCCGTGGTGAGGTTGGCCTGGCCTGGAACACACCACGGATGGCCTACGCCTACATCACCAGTCGCGGTG
CCGCCCAGGCCGGGGTGTGA

Upstream 100 bases:

>100_bases
CAGGGGTTCGAATCCCCTTGGCTCCACCAGGTATCAATCGCCGCCGAAATGGCGGCGGTTTTGTTTTCGAGGTCGTTGTA
AGATGTGCAGCAGGTGAATG

Downstream 100 bases:

>100_bases
TAGCAAATCTTGAGTGGTACTGTCGATCACCTGCGGAACGCGGATGCACGCGGGTCTGGCGGATGGACGCGGATGGATAT
ATGTGCTGGTGATCCGTCCC

Product: asparaginase

Products: NA

Alternate protein names: L-asparagine amidohydrolase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTAEPVQALIVHGGAWAIPDDQVTAHIAGCIAARTAGWQVLQNGGSALDAVEAAVRVMEDDPIFDAGTGSVLTSAGTVEL
DAALMDGRTLRYGAVAGLQRIRNPITLARHVLNGPATMLVGPGAEAFAATVGIPFCDNAELVVERERQLWLAWKAQGSPP
PPPASGHDTVGAIALDQSGQLVAANSTGGTPFKLPGRVGDTPLIGCGLYATADGAAVCTGWGESITRVALARRVVELLED
GMHPQEAAERGIKLLSELVPDGRGGVIVLTPRGEVGLAWNTPRMAYAYITSRGAAQAGV

Sequences:

>Translated_299_residues
MTAEPVQALIVHGGAWAIPDDQVTAHIAGCIAARTAGWQVLQNGGSALDAVEAAVRVMEDDPIFDAGTGSVLTSAGTVEL
DAALMDGRTLRYGAVAGLQRIRNPITLARHVLNGPATMLVGPGAEAFAATVGIPFCDNAELVVERERQLWLAWKAQGSPP
PPPASGHDTVGAIALDQSGQLVAANSTGGTPFKLPGRVGDTPLIGCGLYATADGAAVCTGWGESITRVALARRVVELLED
GMHPQEAAERGIKLLSELVPDGRGGVIVLTPRGEVGLAWNTPRMAYAYITSRGAAQAGV
>Mature_298_residues
TAEPVQALIVHGGAWAIPDDQVTAHIAGCIAARTAGWQVLQNGGSALDAVEAAVRVMEDDPIFDAGTGSVLTSAGTVELD
AALMDGRTLRYGAVAGLQRIRNPITLARHVLNGPATMLVGPGAEAFAATVGIPFCDNAELVVERERQLWLAWKAQGSPPP
PPASGHDTVGAIALDQSGQLVAANSTGGTPFKLPGRVGDTPLIGCGLYATADGAAVCTGWGESITRVALARRVVELLEDG
MHPQEAAERGIKLLSELVPDGRGGVIVLTPRGEVGLAWNTPRMAYAYITSRGAAQAGV

Specific function: Unknown

COG id: COG1446

COG function: function code E; Asparaginase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ntn-hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI145275202, Length=283, Percent_Identity=42.756183745583, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI145275200, Length=283, Percent_Identity=42.756183745583, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI98991769, Length=268, Percent_Identity=34.7014925373134, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI285002251, Length=280, Percent_Identity=32.5, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI285002253, Length=280, Percent_Identity=30.3571428571429, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787050, Length=295, Percent_Identity=40.3389830508475, Blast_Score=174, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17569239, Length=254, Percent_Identity=29.5275590551181, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564649, Length=235, Percent_Identity=27.6595744680851, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI18921183, Length=309, Percent_Identity=38.5113268608414, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI221330102, Length=290, Percent_Identity=32.7586206896552, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24652135, Length=290, Percent_Identity=32.7586206896552, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21357893, Length=264, Percent_Identity=32.5757575757576, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24657358, Length=235, Percent_Identity=31.9148936170213, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655553, Length=263, Percent_Identity=32.319391634981, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000246 [H]

Pfam domain/function: PF01112 Asparaginase_2 [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 30778; Mature: 30647

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEPVQALIVHGGAWAIPDDQVTAHIAGCIAARTAGWQVLQNGGSALDAVEAAVRVMED
CCCCCEEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
DPIFDAGTGSVLTSAGTVELDAALMDGRTLRYGAVAGLQRIRNPITLARHVLNGPATMLV
CCCEECCCCCEEECCCCEEEEHHHHCCCEEEHHHHHHHHHHCCHHHHHHHHHCCCEEEEE
GPGAEAFAATVGIPFCDNAELVVERERQLWLAWKAQGSPPPPPASGHDTVGAIALDQSGQ
CCCHHHHHHEECCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCC
LVAANSTGGTPFKLPGRVGDTPLIGCGLYATADGAAVCTGWGESITRVALARRVVELLED
EEEECCCCCCCEECCCCCCCCCEEECCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHC
GMHPQEAAERGIKLLSELVPDGRGGVIVLTPRGEVGLAWNTPRMAYAYITSRGAAQAGV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TAEPVQALIVHGGAWAIPDDQVTAHIAGCIAARTAGWQVLQNGGSALDAVEAAVRVMED
CCCCEEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
DPIFDAGTGSVLTSAGTVELDAALMDGRTLRYGAVAGLQRIRNPITLARHVLNGPATMLV
CCCEECCCCCEEECCCCEEEEHHHHCCCEEEHHHHHHHHHHCCHHHHHHHHHCCCEEEEE
GPGAEAFAATVGIPFCDNAELVVERERQLWLAWKAQGSPPPPPASGHDTVGAIALDQSGQ
CCCHHHHHHEECCCCCCCCCEEEECCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCC
LVAANSTGGTPFKLPGRVGDTPLIGCGLYATADGAAVCTGWGESITRVALARRVVELLED
EEEECCCCCCCEECCCCCCCCCEEECCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHC
GMHPQEAAERGIKLLSELVPDGRGGVIVLTPRGEVGLAWNTPRMAYAYITSRGAAQAGV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]