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The map label for this gene is yqjD [H]

Identifier: 222526919

GI number: 222526919

Start: 4608919

End: 4610463

Strand: Reverse

Name: yqjD [H]

Synonym: Chy400_3697

Alternate gene names: 222526919

Gene position: 4610463-4608919 (Counterclockwise)

Preceding gene: 222526920

Following gene: 222526918

Centisome position: 87.5

GC content: 57.22

Gene sequence:

>1545_bases
GTGGAAACTCCTGAAGAACAGCTCGCAACACTCTTTCGGCTACGCGAACGAGCGTTGCAAGGTGGTGGCCCTGAGCGCGT
TGCCCAACAACATGCCCGCGGGAAATTGACGGCTCGTGAGCGACTGGCATTGCTCCTCGATCCCAACTCCTTTCAGGAGA
TTGGTGCCCTTGCCAGCAGCCCTCTCGGCGATGAGGATCAACGGGTGCCCGGTGATGGGATCGTGACCGGGTTCGGCAAG
ATCAATGGTCGCCGTGTTGCCGTGTTTGCGCAAGATTTTACCGTGATGGGTGGATCGTTCTCGGCTGTGCAGGCGAATAA
GATTTGCCGCATGCAAGACCTGGCTATCGAGAGCGGTATTCCCATCATCGGGTTGAACGACTCTGGTGGTGCCCGCATTC
AAGAAGGTGTTCGCTCCCTGGCGGCGTATGGTGAGGTCTTCGTGCGCAATGTTATGGCGTCTGGCGTTGTGCCGCAAATA
TCGGCAATCCTTGGCCCCTGCGCCGGTGGCGCTGTCTATTCGCCGGCTTTAACCGACTTCGTGATTATGTCGGAGTCAAC
CGGGTATATGTTCCTGACCGGGCCTGATGTGATCAAAGCAGTGTCCGGGCGCGAACTTTCGACGCAAGAGCTGGGTGGCG
CGGCGGTACACTGCGTGCGGAGCGGTGTCGCGCATCTCTCGGCAGCCGACGACCGGGCCGTGATTGAGTTGATCAAGCGG
CTGCTCAGCTATCTGCCGCAGAACAACAATGAAGACCCACCCCAGATCATGCCCTACGACCGCGCTGATCGGATTGAGCC
GGCCCTCAATAGCCTGGTACCGGCAGACGAGCGGCAGGGATACGACATCCATACCCTGATCAACCTGATCTGCGACTACG
ATAGCTTTCTCGAAATCCAGCCGCTCTTCGCGCCCAATGCTGTGGTTGGCTTTGCCCGTCTTGATGGCTATGCCGTCGGG
ATTGTTGCCAACCAGCCGGCAGTGATGGCCGGTGCGCTTGATATTGACGCCAGCGATAAAATTGCCCGCTTTGTCCGTAT
CTGCGATGCCTTTAATATCCCGCTCATCACCTTTGTTGATACACCGGGATTTCTGCCCGGCGTAGAACAAGAGTACGGTG
GTGTGATTCGCCACGGCGCGAAAATTATTTACGCCTATAGCGAAGCCACTGTACCCAAAATTTCGGTTGTCGTGCGCAAG
GCAATTGGTGGAGCGTATGTCGCAATGTCAAGCAAACAGTTGCGCTGCGATCTCAACTTTGCCTGGCCCTCGGCCCAGAT
TGCGGTGATGGGGGCAGAAGGCGCAGTACGCATTTTGCGCCGTGAAGAATTGCGCACCGCCGAGAATCCTGCTCAACTGA
TGGAGCAGTTTATCGCTGATTACCGCCGCCGGTACTTCAACCCCTATCACGCCGCCGATCTGGGTCAGATTGACGAGGTG
ATCGAACCGGCTGAAACCCGACCACGGCTGATCCGTGCGCTTGAGATTTTGCGCACCAAAGTGCAGCAGAACCCACCCCG
TAAACACGGGTTGTACCCATCATAA

Upstream 100 bases:

>100_bases
CTAAACATTTGCCTGTAGTAGTGAATTCTTTTCCTCGCCACACCTCAATCTCTTCTATACTGCCTTTGCCTGCAATAACA
GCATACAAAGAGGTGTGGTA

Downstream 100 bases:

>100_bases
GCTGGGGGCAAGGCGATGAATGATTTCAGTTTTGGCCTGACCATCACCGTCACAGGGATGAGTCTGGTGTTTAGTGTCCT
GGCATTACTGTGGGGCATTC

Product: Propionyl-CoA carboxylase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
METPEEQLATLFRLRERALQGGGPERVAQQHARGKLTARERLALLLDPNSFQEIGALASSPLGDEDQRVPGDGIVTGFGK
INGRRVAVFAQDFTVMGGSFSAVQANKICRMQDLAIESGIPIIGLNDSGGARIQEGVRSLAAYGEVFVRNVMASGVVPQI
SAILGPCAGGAVYSPALTDFVIMSESTGYMFLTGPDVIKAVSGRELSTQELGGAAVHCVRSGVAHLSAADDRAVIELIKR
LLSYLPQNNNEDPPQIMPYDRADRIEPALNSLVPADERQGYDIHTLINLICDYDSFLEIQPLFAPNAVVGFARLDGYAVG
IVANQPAVMAGALDIDASDKIARFVRICDAFNIPLITFVDTPGFLPGVEQEYGGVIRHGAKIIYAYSEATVPKISVVVRK
AIGGAYVAMSSKQLRCDLNFAWPSAQIAVMGAEGAVRILRREELRTAENPAQLMEQFIADYRRRYFNPYHAADLGQIDEV
IEPAETRPRLIRALEILRTKVQQNPPRKHGLYPS

Sequences:

>Translated_514_residues
METPEEQLATLFRLRERALQGGGPERVAQQHARGKLTARERLALLLDPNSFQEIGALASSPLGDEDQRVPGDGIVTGFGK
INGRRVAVFAQDFTVMGGSFSAVQANKICRMQDLAIESGIPIIGLNDSGGARIQEGVRSLAAYGEVFVRNVMASGVVPQI
SAILGPCAGGAVYSPALTDFVIMSESTGYMFLTGPDVIKAVSGRELSTQELGGAAVHCVRSGVAHLSAADDRAVIELIKR
LLSYLPQNNNEDPPQIMPYDRADRIEPALNSLVPADERQGYDIHTLINLICDYDSFLEIQPLFAPNAVVGFARLDGYAVG
IVANQPAVMAGALDIDASDKIARFVRICDAFNIPLITFVDTPGFLPGVEQEYGGVIRHGAKIIYAYSEATVPKISVVVRK
AIGGAYVAMSSKQLRCDLNFAWPSAQIAVMGAEGAVRILRREELRTAENPAQLMEQFIADYRRRYFNPYHAADLGQIDEV
IEPAETRPRLIRALEILRTKVQQNPPRKHGLYPS
>Mature_514_residues
METPEEQLATLFRLRERALQGGGPERVAQQHARGKLTARERLALLLDPNSFQEIGALASSPLGDEDQRVPGDGIVTGFGK
INGRRVAVFAQDFTVMGGSFSAVQANKICRMQDLAIESGIPIIGLNDSGGARIQEGVRSLAAYGEVFVRNVMASGVVPQI
SAILGPCAGGAVYSPALTDFVIMSESTGYMFLTGPDVIKAVSGRELSTQELGGAAVHCVRSGVAHLSAADDRAVIELIKR
LLSYLPQNNNEDPPQIMPYDRADRIEPALNSLVPADERQGYDIHTLINLICDYDSFLEIQPLFAPNAVVGFARLDGYAVG
IVANQPAVMAGALDIDASDKIARFVRICDAFNIPLITFVDTPGFLPGVEQEYGGVIRHGAKIIYAYSEATVPKISVVVRK
AIGGAYVAMSSKQLRCDLNFAWPSAQIAVMGAEGAVRILRREELRTAENPAQLMEQFIADYRRRYFNPYHAADLGQIDEV
IEPAETRPRLIRALEILRTKVQQNPPRKHGLYPS

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=504, Percent_Identity=52.9761904761905, Blast_Score=539, Evalue=1e-153,
Organism=Homo sapiens, GI295821216, Length=524, Percent_Identity=50.9541984732824, Blast_Score=527, Evalue=1e-150,
Organism=Homo sapiens, GI11545863, Length=512, Percent_Identity=33.203125, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI134142062, Length=361, Percent_Identity=28.2548476454294, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38679977, Length=343, Percent_Identity=26.8221574344023, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38679967, Length=343, Percent_Identity=26.8221574344023, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38679974, Length=343, Percent_Identity=26.8221574344023, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38679971, Length=343, Percent_Identity=26.8221574344023, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38679960, Length=343, Percent_Identity=26.8221574344023, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1788655, Length=185, Percent_Identity=29.1891891891892, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147362, Length=502, Percent_Identity=53.7848605577689, Blast_Score=546, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI25147359, Length=502, Percent_Identity=53.7848605577689, Blast_Score=546, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI17552936, Length=513, Percent_Identity=31.9688109161793, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71997163, Length=311, Percent_Identity=27.0096463022508, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323863, Length=235, Percent_Identity=28.5106382978723, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324343, Length=303, Percent_Identity=24.7524752475248, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586065, Length=516, Percent_Identity=32.7519379844961, Blast_Score=250, Evalue=2e-66,
Organism=Drosophila melanogaster, GI161076407, Length=341, Percent_Identity=26.6862170087977, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24586460, Length=341, Percent_Identity=26.6862170087977, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24586458, Length=341, Percent_Identity=26.6862170087977, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161076409, Length=341, Percent_Identity=26.6862170087977, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 55801; Mature: 55801

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METPEEQLATLFRLRERALQGGGPERVAQQHARGKLTARERLALLLDPNSFQEIGALASS
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHCEEEEECCCCHHHHHHHHCC
PLGDEDQRVPGDGIVTGFGKINGRRVAVFAQDFTVMGGSFSAVQANKICRMQDLAIESGI
CCCCCCCCCCCCCEEEECCCCCCCEEEEEEECEEEECCCCCHHHHHHHHHHHHHHHHCCC
PIIGLNDSGGARIQEGVRSLAAYGEVFVRNVMASGVVPQISAILGPCAGGAVYSPALTDF
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHEE
VIMSESTGYMFLTGPDVIKAVSGRELSTQELGGAAVHCVRSGVAHLSAADDRAVIELIKR
EEEECCCCEEEEECHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LLSYLPQNNNEDPPQIMPYDRADRIEPALNSLVPADERQGYDIHTLINLICDYDSFLEIQ
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
PLFAPNAVVGFARLDGYAVGIVANQPAVMAGALDIDASDKIARFVRICDAFNIPLITFVD
ECCCCCCEEEEEECCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEC
TPGFLPGVEQEYGGVIRHGAKIIYAYSEATVPKISVVVRKAIGGAYVAMSSKQLRCDLNF
CCCCCCCCCHHHCHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCEEEEEEEE
AWPSAQIAVMGAEGAVRILRREELRTAENPAQLMEQFIADYRRRYFNPYHAADLGQIDEV
CCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IEPAETRPRLIRALEILRTKVQQNPPRKHGLYPS
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
METPEEQLATLFRLRERALQGGGPERVAQQHARGKLTARERLALLLDPNSFQEIGALASS
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHCEEEEECCCCHHHHHHHHCC
PLGDEDQRVPGDGIVTGFGKINGRRVAVFAQDFTVMGGSFSAVQANKICRMQDLAIESGI
CCCCCCCCCCCCCEEEECCCCCCCEEEEEEECEEEECCCCCHHHHHHHHHHHHHHHHCCC
PIIGLNDSGGARIQEGVRSLAAYGEVFVRNVMASGVVPQISAILGPCAGGAVYSPALTDF
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHEE
VIMSESTGYMFLTGPDVIKAVSGRELSTQELGGAAVHCVRSGVAHLSAADDRAVIELIKR
EEEECCCCEEEEECHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LLSYLPQNNNEDPPQIMPYDRADRIEPALNSLVPADERQGYDIHTLINLICDYDSFLEIQ
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEE
PLFAPNAVVGFARLDGYAVGIVANQPAVMAGALDIDASDKIARFVRICDAFNIPLITFVD
ECCCCCCEEEEEECCCEEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEC
TPGFLPGVEQEYGGVIRHGAKIIYAYSEATVPKISVVVRKAIGGAYVAMSSKQLRCDLNF
CCCCCCCCCHHHCHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCEEEEEEEE
AWPSAQIAVMGAEGAVRILRREELRTAENPAQLMEQFIADYRRRYFNPYHAADLGQIDEV
CCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
IEPAETRPRLIRALEILRTKVQQNPPRKHGLYPS
HCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]