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The map label for this gene is pkn1 [H]

Identifier: 222526295

GI number: 222526295

Start: 3777724

End: 3778533

Strand: Reverse

Name: pkn1 [H]

Synonym: Chy400_3061

Alternate gene names: 222526295

Gene position: 3778533-3777724 (Counterclockwise)

Preceding gene: 222526296

Following gene: 222526294

Centisome position: 71.71

GC content: 59.26

Gene sequence:

>810_bases
ATGAGCAGGCTTACTGAATTATTACCGGTTTTTATACACATTCCGTCACGTCCCTTTCGCATGGGCACACCTGTGAGCGA
CATCAGTGACCTGGCCCGTCACTATGGCGGCACTCGCGAAAGCTACCGTGAAGAGACACCACAACACGAACTGACGCTTC
CGGCATTTGCCATTGCACAACATCCGCTGAGCAATGCCCTCTACGCCTGCGCTGTTGCTGATGGAGCTGTGCCACCACCT
CCCGCCTGGCATGGCACGACCCCGCCGGACAAACTGGCAGCATTACCGGTCACCGACATCACCTGGTACGAAGCCATGGC
CTTCTGCGCCTGGCTGAGTCAACAATCCGGTCTGTCCCTCCGCCTGATCGACCCGAACGGTCAGCCGGTTACGCCACCTC
CTGTGTTGCGCTTTCGCCTGCCAACCGAAGCGGAATGGGAGCACGCCGCCCGCGGCACCGACGGTCGGCGCTTCCCGTGG
GGCGAGACATTTCATCCCGATTACGCCAATACGCGCGAGGGGGGACGATCAGCACCTAACCCGCCCGGCACATACCCTGC
CGGACAGAGTCCGTATGGTGTTGAAGATATGGCCGGTAATGTATGGGAATGGACAGCATCGCTCGACCGGGAATATCCCT
ACCGACCCGATGATGGACGTGAAGACCCAACCGCAACCGGGAGACGGATTTTACGCGGCGGTTGTTACGCCAATCCCCAG
GGGTATGCACGCTGTGCCTGTCGTTTTCGACTACAACCGACGATGCGCAACCAGTTTCTGGGCATGCGCCTTGCACTAGA
CCTGGAATAA

Upstream 100 bases:

>100_bases
GGCGCGGCTATGATGCCCTACAGAACGTGACATCCATCGATCATTTCGCCGAGACGATCTACCAGCGTGAGCTAGATCGG
CTCAATCGGATTTATCAACG

Downstream 100 bases:

>100_bases
TTAAGGAGCATTCGCTTTATGAACCCAGCCAAAACGCTTAAATTAGGCCGCAACGATCCCTGCCACTGTGGTAGTGGGCG
CAAATACAAGGATTGCCATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSRLTELLPVFIHIPSRPFRMGTPVSDISDLARHYGGTRESYREETPQHELTLPAFAIAQHPLSNALYACAVADGAVPPP
PAWHGTTPPDKLAALPVTDITWYEAMAFCAWLSQQSGLSLRLIDPNGQPVTPPPVLRFRLPTEAEWEHAARGTDGRRFPW
GETFHPDYANTREGGRSAPNPPGTYPAGQSPYGVEDMAGNVWEWTASLDREYPYRPDDGREDPTATGRRILRGGCYANPQ
GYARCACRFRLQPTMRNQFLGMRLALDLE

Sequences:

>Translated_269_residues
MSRLTELLPVFIHIPSRPFRMGTPVSDISDLARHYGGTRESYREETPQHELTLPAFAIAQHPLSNALYACAVADGAVPPP
PAWHGTTPPDKLAALPVTDITWYEAMAFCAWLSQQSGLSLRLIDPNGQPVTPPPVLRFRLPTEAEWEHAARGTDGRRFPW
GETFHPDYANTREGGRSAPNPPGTYPAGQSPYGVEDMAGNVWEWTASLDREYPYRPDDGREDPTATGRRILRGGCYANPQ
GYARCACRFRLQPTMRNQFLGMRLALDLE
>Mature_268_residues
SRLTELLPVFIHIPSRPFRMGTPVSDISDLARHYGGTRESYREETPQHELTLPAFAIAQHPLSNALYACAVADGAVPPPP
AWHGTTPPDKLAALPVTDITWYEAMAFCAWLSQQSGLSLRLIDPNGQPVTPPPVLRFRLPTEAEWEHAARGTDGRRFPWG
ETFHPDYANTREGGRSAPNPPGTYPAGQSPYGVEDMAGNVWEWTASLDREYPYRPDDGREDPTATGRRILRGGCYANPQG
YARCACRFRLQPTMRNQFLGMRLALDLE

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248088, Length=225, Percent_Identity=30.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI194248087, Length=271, Percent_Identity=28.4132841328413, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226437577, Length=225, Percent_Identity=30.6666666666667, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI257470975, Length=289, Percent_Identity=27.3356401384083, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI38202250, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20130397, Length=193, Percent_Identity=29.5336787564767, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 29972; Mature: 29841

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLTELLPVFIHIPSRPFRMGTPVSDISDLARHYGGTRESYREETPQHELTLPAFAIAQ
CCHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHH
HPLSNALYACAVADGAVPPPPAWHGTTPPDKLAALPVTDITWYEAMAFCAWLSQQSGLSL
CCHHHHHEEEHHCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHCCCCEE
RLIDPNGQPVTPPPVLRFRLPTEAEWEHAARGTDGRRFPWGETFHPDYANTREGGRSAPN
EEECCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPGTYPAGQSPYGVEDMAGNVWEWTASLDREYPYRPDDGREDPTATGRRILRGGCYANPQ
CCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
GYARCACRFRLQPTMRNQFLGMRLALDLE
HHEEEEEEEECCHHHHHHHCCEEEEEECC
>Mature Secondary Structure 
SRLTELLPVFIHIPSRPFRMGTPVSDISDLARHYGGTRESYREETPQHELTLPAFAIAQ
CHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHH
HPLSNALYACAVADGAVPPPPAWHGTTPPDKLAALPVTDITWYEAMAFCAWLSQQSGLSL
CCHHHHHEEEHHCCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHHHCCCCEE
RLIDPNGQPVTPPPVLRFRLPTEAEWEHAARGTDGRRFPWGETFHPDYANTREGGRSAPN
EEECCCCCCCCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PPGTYPAGQSPYGVEDMAGNVWEWTASLDREYPYRPDDGREDPTATGRRILRGGCYANPQ
CCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
GYARCACRFRLQPTMRNQFLGMRLALDLE
HHEEEEEEEECCHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]