Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 222526281

GI number: 222526281

Start: 3757825

End: 3758421

Strand: Reverse

Name: pgsA [H]

Synonym: Chy400_3047

Alternate gene names: 222526281

Gene position: 3758421-3757825 (Counterclockwise)

Preceding gene: 222526287

Following gene: 222526278

Centisome position: 71.33

GC content: 55.11

Gene sequence:

>597_bases
ATGCGTCAGCTTCCAAATTTGCTAGGTCTCTTCCGTATTCTTGCTACACCTGTCCTGGCCTGGATGGTACTGCTTGCCTC
GCCGACCGCCTATCTGGGCGCAGCCATTCTACTGTTGCTGATGGCGTTGAGTGATATGGCCGACGGTCGCTTGGCCCGCC
ATCTGAAGGTTGTTTCACCTCTCGGCGTTTTTATCGACACAATTAGTGATAAGATTTTCGTTGCCGGCGTTCTCATTCCA
ATGATTGAAACCGGGCTGATTCCAGCCTGGATTGCACTCACCATCATTATCCGGGAGTTTGTTGTTTCCGGTCTCCGCTC
ATTTGCCGCTGCCGAAGGGATTGTGATCTCAGCCCGTCGCTTTGGGAAGCAGAAGCTGGTGATTACGGTCGTGGCATTGA
TCTGGCGGTTACTGGCTGCCCATGCCGAGATCGGTGGTTTTCTCGGTGTTATCTTCGGCGGTAGTCTTGTCCCGCTGCTG
AATCTGTGGCCGGTTGTTATGGGGCTGGCATTGATCTGGACGGTCGGTTCAGGGATCGAATACCTCTGGCAGGCATGGCC
GCTGTTGCGCCGGGGATGGACGCCGAAGGCATCGTGA

Upstream 100 bases:

>100_bases
AGACACAACTACTGGAATAAATGTTATTTATGTCAAGTAAACAAGGACAGTTTGTGCTATAATCGAGGTTGCAGAGCAGG
CTTAGAACTGAGAAATTACC

Downstream 100 bases:

>100_bases
ACAGGATTGATCATTCCGCAGCGCAATAACCTCTAGTGGTTAGTACAGATTTCAGCCCGTACCACACCGCATTGAGTGTC
AGGCTTACCGGTTGAACATC

Product: CDP-alcohol phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MRQLPNLLGLFRILATPVLAWMVLLASPTAYLGAAILLLLMALSDMADGRLARHLKVVSPLGVFIDTISDKIFVAGVLIP
MIETGLIPAWIALTIIIREFVVSGLRSFAAAEGIVISARRFGKQKLVITVVALIWRLLAAHAEIGGFLGVIFGGSLVPLL
NLWPVVMGLALIWTVGSGIEYLWQAWPLLRRGWTPKAS

Sequences:

>Translated_198_residues
MRQLPNLLGLFRILATPVLAWMVLLASPTAYLGAAILLLLMALSDMADGRLARHLKVVSPLGVFIDTISDKIFVAGVLIP
MIETGLIPAWIALTIIIREFVVSGLRSFAAAEGIVISARRFGKQKLVITVVALIWRLLAAHAEIGGFLGVIFGGSLVPLL
NLWPVVMGLALIWTVGSGIEYLWQAWPLLRRGWTPKAS
>Mature_198_residues
MRQLPNLLGLFRILATPVLAWMVLLASPTAYLGAAILLLLMALSDMADGRLARHLKVVSPLGVFIDTISDKIFVAGVLIP
MIETGLIPAWIALTIIIREFVVSGLRSFAAAEGIVISARRFGKQKLVITVVALIWRLLAAHAEIGGFLGVIFGGSLVPLL
NLWPVVMGLALIWTVGSGIEYLWQAWPLLRRGWTPKAS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=140, Percent_Identity=30.7142857142857, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21471; Mature: 21471

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQLPNLLGLFRILATPVLAWMVLLASPTAYLGAAILLLLMALSDMADGRLARHLKVVSP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LGVFIDTISDKIFVAGVLIPMIETGLIPAWIALTIIIREFVVSGLRSFAAAEGIVISARR
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FGKQKLVITVVALIWRLLAAHAEIGGFLGVIFGGSLVPLLNLWPVVMGLALIWTVGSGIE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWQAWPLLRRGWTPKAS
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRQLPNLLGLFRILATPVLAWMVLLASPTAYLGAAILLLLMALSDMADGRLARHLKVVSP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LGVFIDTISDKIFVAGVLIPMIETGLIPAWIALTIIIREFVVSGLRSFAAAEGIVISARR
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FGKQKLVITVVALIWRLLAAHAEIGGFLGVIFGGSLVPLLNLWPVVMGLALIWTVGSGIE
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWQAWPLLRRGWTPKAS
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA