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The map label for this gene is hypA

Identifier: 222526236

GI number: 222526236

Start: 3701870

End: 3702214

Strand: Reverse

Name: hypA

Synonym: Chy400_2999

Alternate gene names: 222526236

Gene position: 3702214-3701870 (Counterclockwise)

Preceding gene: 222526237

Following gene: 222526235

Centisome position: 70.26

GC content: 60.87

Gene sequence:

>345_bases
ATGCACGAATTATCGATTGCGCACAACATCGTGACGATTGCCAGCGATGCTGCGGCAGAAGCAGGAGTGGATCGGATCAG
CGCCGTTCACCTGCGGATCGGCGCCCTCGCTGGGGTGGTCGCCGATGCGCTTCGCTTCAGCTTCGCCATCGCCGCCGAAG
GCACACCGCTGGCCGGGGCTGAACTGATTATCGAAGAGGTGCCGGTGGTCGTCTTTTGCCCGGATTGCAACGCCGAAGTG
ACGCTGACGAACCCACGGCTGTTCCGCTGTCCACGGTGTGATCGCCCCTGCGGTCAGATCGTTCATGGACGTGAGTTAGA
ACTGGTTGCACTGGAGACACCATGA

Upstream 100 bases:

>100_bases
TTTGGTCTGCTCCGGGCGTTACGCGATCCCGATGTGCAACGCGCTGCCGGGCTGATTGTTGAATTCGGTCGCCGCTTTGG
TCGTTCGCTGAAATAGGCTG

Downstream 100 bases:

>100_bases
CCTACGAGACAAAACGGCTGATCGAAATTCGCCAGGGCGTGTTGAACAAGAACGATCAACTCGCTGCCGCGTTACGACAC
CGCTTTCACGCCGCCGGCGT

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGAELIIEEVPVVVFCPDCNAEV
TLTNPRLFRCPRCDRPCGQIVHGRELELVALETP

Sequences:

>Translated_114_residues
MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGAELIIEEVPVVVFCPDCNAEV
TLTNPRLFRCPRCDRPCGQIVHGRELELVALETP
>Mature_114_residues
MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGAELIIEEVPVVVFCPDCNAEV
TLTNPRLFRCPRCDRPCGQIVHGRELELVALETP

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789081, Length=110, Percent_Identity=32.7272727272727, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1789365, Length=93, Percent_Identity=39.7849462365591, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_CHLAA (A9WK98)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001636365.1
- GeneID:   5827245
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_2774
- HOGENOM:   HBG688671
- OMA:   IAGNEFF
- ProtClustDB:   CLSK954182
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12054; Mature: 12054

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGA
CCCCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCH
ELIIEEVPVVVFCPDCNAEVTLTNPRLFRCPRCDRPCGQIVHGRELELVALETP
HHHEECCCEEEECCCCCCEEEECCCCEEECCCCCCCCHHCCCCCCEEEEEEECC
>Mature Secondary Structure
MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGA
CCCCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCH
ELIIEEVPVVVFCPDCNAEVTLTNPRLFRCPRCDRPCGQIVHGRELELVALETP
HHHEECCCEEEECCCCCCEEEECCCCEEECCCCCCCCHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA