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The map label for this gene is hypB [H]

Identifier: 222526235

GI number: 222526235

Start: 3701178

End: 3701873

Strand: Reverse

Name: hypB [H]

Synonym: Chy400_2998

Alternate gene names: 222526235

Gene position: 3701873-3701178 (Counterclockwise)

Preceding gene: 222526236

Following gene: 222526234

Centisome position: 70.26

GC content: 59.48

Gene sequence:

>696_bases
ATGACCTACGAGACAAAACGGCTGATCGAAATTCGCCAGGGCGTGTTGAACAAGAACGATCAACTCGCTGCCGCGTTACG
ACACCGCTTTCACGCCGCCGGCGTGACGGTTGTCAATCTGCTGTCCAGTCCGGGCGCCGGCAAAACCAGCCTGCTCGAAG
CGACGATGCGCATGATGCTGGCCGAGTGCCGGGTCGCGGCCCTGGTCGGCGATCTGGCTACCGACAACGATGCCCGTCGG
CTGGCACGCAGTGGTGGGCTGGTACGGCAGATACAGACCGGCGATATGTGTCATCTCGAAGCCGACATCGTTGCCCGCCA
TCTCGCCGATTGGGACCTCAACCAGATCGATCTCCTCTTTATCGAGAACGTTGGGAATCTGGTGTGTCCCGCCGGCTACG
ATCTCGGCGAAGCGGTGCGCGTGGTCCTACTCTCTACGACTGAAGGTGAAGACAAACCGTTGAAGTATCCGGCGACCTTT
GCCACCGCCGATGCGGTCATCCTGACCAAGATGGACCTGGCAGAACCGGTGGGGTTTGATCGGGTGAGCGCCGAGACTAA
TATTCGCGCTGTTAATCCTCTCGCCCCGATCATTGCCACCTCTGCCCGTAGCGAGGCCGGCCTGCAAGAGTGGCTAAACT
GGCTGCGAGATCAGATGCGAACACGATCATCAAACGCAAAAACCCCATCAGCGTAG

Upstream 100 bases:

>100_bases
CGCTGACGAACCCACGGCTGTTCCGCTGTCCACGGTGTGATCGCCCCTGCGGTCAGATCGTTCATGGACGTGAGTTAGAA
CTGGTTGCACTGGAGACACC

Downstream 100 bases:

>100_bases
CGCTGTTTAGGGAAGTCTGGCGTCGTGAAGGAGTTGGACAGAACCGGTAGGGTTTGATCGGGTGAGTGCCGAGACTCATA
TTCGCGCTGTTAATCCTCTC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTYETKRLIEIRQGVLNKNDQLAAALRHRFHAAGVTVVNLLSSPGAGKTSLLEATMRMMLAECRVAALVGDLATDNDARR
LARSGGLVRQIQTGDMCHLEADIVARHLADWDLNQIDLLFIENVGNLVCPAGYDLGEAVRVVLLSTTEGEDKPLKYPATF
ATADAVILTKMDLAEPVGFDRVSAETNIRAVNPLAPIIATSARSEAGLQEWLNWLRDQMRTRSSNAKTPSA

Sequences:

>Translated_231_residues
MTYETKRLIEIRQGVLNKNDQLAAALRHRFHAAGVTVVNLLSSPGAGKTSLLEATMRMMLAECRVAALVGDLATDNDARR
LARSGGLVRQIQTGDMCHLEADIVARHLADWDLNQIDLLFIENVGNLVCPAGYDLGEAVRVVLLSTTEGEDKPLKYPATF
ATADAVILTKMDLAEPVGFDRVSAETNIRAVNPLAPIIATSARSEAGLQEWLNWLRDQMRTRSSNAKTPSA
>Mature_230_residues
TYETKRLIEIRQGVLNKNDQLAAALRHRFHAAGVTVVNLLSSPGAGKTSLLEATMRMMLAECRVAALVGDLATDNDARRL
ARSGGLVRQIQTGDMCHLEADIVARHLADWDLNQIDLLFIENVGNLVCPAGYDLGEAVRVVLLSTTEGEDKPLKYPATFA
TADAVILTKMDLAEPVGFDRVSAETNIRAVNPLAPIIATSARSEAGLQEWLNWLRDQMRTRSSNAKTPSA

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=213, Percent_Identity=46.4788732394366, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 25150; Mature: 25019

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYETKRLIEIRQGVLNKNDQLAAALRHRFHAAGVTVVNLLSSPGAGKTSLLEATMRMML
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AECRVAALVGDLATDNDARRLARSGGLVRQIQTGDMCHLEADIVARHLADWDLNQIDLLF
HHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCCEEEEE
IENVGNLVCPAGYDLGEAVRVVLLSTTEGEDKPLKYPATFATADAVILTKMDLAEPVGFD
EECCCCEECCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHCCCEEEHHHHHCCCCCC
RVSAETNIRAVNPLAPIIATSARSEAGLQEWLNWLRDQMRTRSSNAKTPSA
CCCCCCCCEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TYETKRLIEIRQGVLNKNDQLAAALRHRFHAAGVTVVNLLSSPGAGKTSLLEATMRMML
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AECRVAALVGDLATDNDARRLARSGGLVRQIQTGDMCHLEADIVARHLADWDLNQIDLLF
HHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCCEEEEE
IENVGNLVCPAGYDLGEAVRVVLLSTTEGEDKPLKYPATFATADAVILTKMDLAEPVGFD
EECCCCEECCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHCCCEEEHHHHHCCCCCC
RVSAETNIRAVNPLAPIIATSARSEAGLQEWLNWLRDQMRTRSSNAKTPSA
CCCCCCCCEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]