Click here to switch to the map view.

The map label for this gene is cobL [H]

Identifier: 222526019

GI number: 222526019

Start: 3420071

End: 3421291

Strand: Reverse

Name: cobL [H]

Synonym: Chy400_2775

Alternate gene names: 222526019

Gene position: 3421291-3420071 (Counterclockwise)

Preceding gene: 222526020

Following gene: 222526018

Centisome position: 64.93

GC content: 63.14

Gene sequence:

>1221_bases
ATGAGTCGACGCACGCCCATTCTTGTGGTTGGATTGACGGCTGCCGGCAGCGACGGTCTGTCATCCGCGCTGATCGAGCG
CGTGCTCCGCGCCGATCTGCTGGTAGGCGGGCGACGGCACCTGGCGGCGTTTCCTGATTTTGCCGGCGAACGGTTAACGA
TAGAGGCGAGTGTGGAACCGGCGCTGACCCGTCTGCACGCAGCGTGGCAAAACGGCGAGGTGGCAGTGGTGCTGGCGTCG
GGTGATCCACTCTGGTACGGCATCGGCAGCAGTCTGCGCCGTGTGTTTCCGCCAGACGCACTGGAAATCGTGCCGGCACC
AACCTCGGCGCAACTCGCATTTGCGGCGCTGGCCGAACCCTGGCACGATGCGGTCTTGCTCAGCGCGCACGGACGCCCGT
TAGCAGCCATCATTCCTGCTGTGCTCACCGCGTCCAAAGCGGCAATTCTCACCGATCACCATCAGACACCGGCTGTCGTT
GCGCAGGCACTCATCGCCGCCGGTCTGGCGCCAGAAAGCCGCTGCGCCGTCTGTGAACAGCTTGGCGGTACGAAACAGCG
AATCGTCCAGGCCACTCTCACCGACATTGCAGAGGCGACCTTTGACCCCCTGAATGTCTTGATCGTCTGGAACGACCATC
CCCGCCGACCATTTCCACCCGGCCTTACCGATGAAGCCTTCAGCACTGAAGCCGGCCAACTGACCAAGCGCGAAGTACGT
CTGCTGAGCCTGGCCGAACTGGCTTTGCAACCGGGTGAGGTGATGTGGGACATCGGTGCCGGCAGCGGCGCGGTCGCTAT
CGAAGCTGCGCGCGCCTGCCCAACCGCGCAAGTCTACGCGGTCGAGCGGCGTGCCACCTTTATCGGTCATATCCAGACCA
ACCTGGTGCGCTTTCCGGCGCCCAATCTGCACATCACGCACGGCGAAGCTCCGGCAGCCTGCCATGACTTGCCCGATCCG
CACGCCATCTTTGTCGGTGGTAGTGGCGGGCGCCTTGCCGAAATCGTGGCTCTGGCCCGCCACCGACTACGACCCGGTGG
CAGACTGGTGCTCAACCTGATAATGACCGGCCATCTCGCCGAGGCGGTGCAGCTTTTGCCCACCGCACGGGTTACCCAGA
TTCAAGTCAATCGCGGCACGCCCATCCAATCCGATCTACGCTTTGCCGCACTCAACCCGGTGTACATCGTTGTCTGGCGG
AATGAGGAACACCATGACTGA

Upstream 100 bases:

>100_bases
CAGCACCGGCGCATACCAGACCGGCGTCGCTGCCGGCACCGCTGATCGAGCGTCTACCCAACGATCCGTTGCCTGAAACT
GATGAGCCGGTGGAGGATGC

Downstream 100 bases:

>100_bases
CACACCAGAACTGATCGCGGTCGGGCTTGGCCCCGGCGATCCCGAACTGATTACGGTTAAGGGGCTACGTGCTATTCAGG
CGGCTGATGTGATCTTTGCG

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSRRTPILVVGLTAAGSDGLSSALIERVLRADLLVGGRRHLAAFPDFAGERLTIEASVEPALTRLHAAWQNGEVAVVLAS
GDPLWYGIGSSLRRVFPPDALEIVPAPTSAQLAFAALAEPWHDAVLLSAHGRPLAAIIPAVLTASKAAILTDHHQTPAVV
AQALIAAGLAPESRCAVCEQLGGTKQRIVQATLTDIAEATFDPLNVLIVWNDHPRRPFPPGLTDEAFSTEAGQLTKREVR
LLSLAELALQPGEVMWDIGAGSGAVAIEAARACPTAQVYAVERRATFIGHIQTNLVRFPAPNLHITHGEAPAACHDLPDP
HAIFVGGSGGRLAEIVALARHRLRPGGRLVLNLIMTGHLAEAVQLLPTARVTQIQVNRGTPIQSDLRFAALNPVYIVVWR
NEEHHD

Sequences:

>Translated_406_residues
MSRRTPILVVGLTAAGSDGLSSALIERVLRADLLVGGRRHLAAFPDFAGERLTIEASVEPALTRLHAAWQNGEVAVVLAS
GDPLWYGIGSSLRRVFPPDALEIVPAPTSAQLAFAALAEPWHDAVLLSAHGRPLAAIIPAVLTASKAAILTDHHQTPAVV
AQALIAAGLAPESRCAVCEQLGGTKQRIVQATLTDIAEATFDPLNVLIVWNDHPRRPFPPGLTDEAFSTEAGQLTKREVR
LLSLAELALQPGEVMWDIGAGSGAVAIEAARACPTAQVYAVERRATFIGHIQTNLVRFPAPNLHITHGEAPAACHDLPDP
HAIFVGGSGGRLAEIVALARHRLRPGGRLVLNLIMTGHLAEAVQLLPTARVTQIQVNRGTPIQSDLRFAALNPVYIVVWR
NEEHHD
>Mature_405_residues
SRRTPILVVGLTAAGSDGLSSALIERVLRADLLVGGRRHLAAFPDFAGERLTIEASVEPALTRLHAAWQNGEVAVVLASG
DPLWYGIGSSLRRVFPPDALEIVPAPTSAQLAFAALAEPWHDAVLLSAHGRPLAAIIPAVLTASKAAILTDHHQTPAVVA
QALIAAGLAPESRCAVCEQLGGTKQRIVQATLTDIAEATFDPLNVLIVWNDHPRRPFPPGLTDEAFSTEAGQLTKREVRL
LSLAELALQPGEVMWDIGAGSGAVAIEAARACPTAQVYAVERRATFIGHIQTNLVRFPAPNLHITHGEAPAACHDLPDPH
AIFVGGSGGRLAEIVALARHRLRPGGRLVLNLIMTGHLAEAVQLLPTARVTQIQVNRGTPIQSDLRFAALNPVYIVVWRN
EEHHD

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 43247; Mature: 43116

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRTPILVVGLTAAGSDGLSSALIERVLRADLLVGGRRHLAAFPDFAGERLTIEASVEP
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEEEEEECCCH
ALTRLHAAWQNGEVAVVLASGDPLWYGIGSSLRRVFPPDALEIVPAPTSAQLAFAALAEP
HHHHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHCC
WHDAVLLSAHGRPLAAIIPAVLTASKAAILTDHHQTPAVVAQALIAAGLAPESRCAVCEQ
CCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHH
LGGTKQRIVQATLTDIAEATFDPLNVLIVWNDHPRRPFPPGLTDEAFSTEAGQLTKREVR
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LLSLAELALQPGEVMWDIGAGSGAVAIEAARACPTAQVYAVERRATFIGHIQTNLVRFPA
HHHHHHHHCCCCCEEEEECCCCCEEEEEEHHCCCCEEEEEEEHHHHEEEEHHHCEEECCC
PNLHITHGEAPAACHDLPDPHAIFVGGSGGRLAEIVALARHRLRPGGRLVLNLIMTGHLA
CCEEEECCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
EAVQLLPTARVTQIQVNRGTPIQSDLRFAALNPVYIVVWRNEEHHD
HHHHHCCCCEEEEEEECCCCCCHHCCEEEECCCEEEEEECCCCCCC
>Mature Secondary Structure 
SRRTPILVVGLTAAGSDGLSSALIERVLRADLLVGGRRHLAAFPDFAGERLTIEASVEP
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCEEEEEECCCH
ALTRLHAAWQNGEVAVVLASGDPLWYGIGSSLRRVFPPDALEIVPAPTSAQLAFAALAEP
HHHHHHHHCCCCCEEEEEECCCCEEECCCHHHHHHCCCCCEEEEECCCCHHHHHHHHHCC
WHDAVLLSAHGRPLAAIIPAVLTASKAAILTDHHQTPAVVAQALIAAGLAPESRCAVCEQ
CCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHH
LGGTKQRIVQATLTDIAEATFDPLNVLIVWNDHPRRPFPPGLTDEAFSTEAGQLTKREVR
HCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
LLSLAELALQPGEVMWDIGAGSGAVAIEAARACPTAQVYAVERRATFIGHIQTNLVRFPA
HHHHHHHHCCCCCEEEEECCCCCEEEEEEHHCCCCEEEEEEEHHHHEEEEHHHCEEECCC
PNLHITHGEAPAACHDLPDPHAIFVGGSGGRLAEIVALARHRLRPGGRLVLNLIMTGHLA
CCEEEECCCCCCHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
EAVQLLPTARVTQIQVNRGTPIQSDLRFAALNPVYIVVWRNEEHHD
HHHHHCCCCEEEEEEECCCCCCHHCCEEEECCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]