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The map label for this gene is cbiL [H]

Identifier: 222526018

GI number: 222526018

Start: 3419350

End: 3420078

Strand: Reverse

Name: cbiL [H]

Synonym: Chy400_2774

Alternate gene names: 222526018

Gene position: 3420078-3419350 (Counterclockwise)

Preceding gene: 222526019

Following gene: 222526017

Centisome position: 64.91

GC content: 60.49

Gene sequence:

>729_bases
ATGACTGACACACCAGAACTGATCGCGGTCGGGCTTGGCCCCGGCGATCCCGAACTGATTACGGTTAAGGGGCTACGTGC
TATTCAGGCGGCTGATGTGATCTTTGCGCCGCAGAGTCGCGATGGCGATGCCAGTATTGCGCTCCAGATTGCCACCCCGT
GGATCGATCAATCGCGACAGCGCATTATCACGCTCCCCCTGCCCATGACCCGCGACTCCGGACAGTTACGCCCGGCGTGG
CAGGCCGCTGCGACCGTGATGCAGCAGGAATTCGGCCAACACCGCCGCGGTGTCTACCTGTTGCTCGGCGATCCCCTGCT
CTACGGCACATTCGTCTACCTCTGGCGCGAGCTGCGTGCTGCGGCGCCAGACATCACGGTCAGCATTATCCCTGGCATCA
CCTCATTTGCCGCTGCCGCTGCCGCCGGTGGCATCCCACTCACCATGGCCGATGAGCGCCTGATCGTGGTGCCGGCCAGT
TACGAAACCGATGCCGGTGCTCTGCAACGACTGCTCAGCGATTTTACCACCGTCGTGTTGATGAAAGCAGGCACAGCATT
GCCGGCTATCGTCGCGGCACTACACCAGCTCAACCTGATCGATCACGCCCTCTACGCCGAACGGGTTGGCTTAGCCGGTG
AGTTTATCACTCGTGATCTGCGCACACTCGACCTGAACCATCGTCCGTATCTGTCACTCGTAATTGTTCGTCGCGGAGAG
CTACTATGA

Upstream 100 bases:

>100_bases
ACCCAGATTCAAGTCAATCGCGGCACGCCCATCCAATCCGATCTACGCTTTGCCGCACTCAACCCGGTGTACATCGTTGT
CTGGCGGAATGAGGAACACC

Downstream 100 bases:

>100_bases
CCTACCCTGCTATTCCAGGAACTGTCTACTTCGTGGGTGCCGGCCCCGGTGCACCCGATTTGATAACAGTGCGTGGCCGT
GATCTGCTGGCCCAGGCCGA

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTDTPELIAVGLGPGDPELITVKGLRAIQAADVIFAPQSRDGDASIALQIATPWIDQSRQRIITLPLPMTRDSGQLRPAW
QAAATVMQQEFGQHRRGVYLLLGDPLLYGTFVYLWRELRAAAPDITVSIIPGITSFAAAAAAGGIPLTMADERLIVVPAS
YETDAGALQRLLSDFTTVVLMKAGTALPAIVAALHQLNLIDHALYAERVGLAGEFITRDLRTLDLNHRPYLSLVIVRRGE
LL

Sequences:

>Translated_242_residues
MTDTPELIAVGLGPGDPELITVKGLRAIQAADVIFAPQSRDGDASIALQIATPWIDQSRQRIITLPLPMTRDSGQLRPAW
QAAATVMQQEFGQHRRGVYLLLGDPLLYGTFVYLWRELRAAAPDITVSIIPGITSFAAAAAAGGIPLTMADERLIVVPAS
YETDAGALQRLLSDFTTVVLMKAGTALPAIVAALHQLNLIDHALYAERVGLAGEFITRDLRTLDLNHRPYLSLVIVRRGE
LL
>Mature_241_residues
TDTPELIAVGLGPGDPELITVKGLRAIQAADVIFAPQSRDGDASIALQIATPWIDQSRQRIITLPLPMTRDSGQLRPAWQ
AAATVMQQEFGQHRRGVYLLLGDPLLYGTFVYLWRELRAAAPDITVSIIPGITSFAAAAAAGGIPLTMADERLIVVPASY
ETDAGALQRLLSDFTTVVLMKAGTALPAIVAALHQLNLIDHALYAERVGLAGEFITRDLRTLDLNHRPYLSLVIVRRGEL
L

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 26182; Mature: 26051

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTPELIAVGLGPGDPELITVKGLRAIQAADVIFAPQSRDGDASIALQIATPWIDQSRQ
CCCCCCEEEEECCCCCCCEEEECCCHHHHHCCEEECCCCCCCCCEEEEEEECCCCCCCCC
RIITLPLPMTRDSGQLRPAWQAAATVMQQEFGQHRRGVYLLLGDPLLYGTFVYLWRELRA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHH
AAPDITVSIIPGITSFAAAAAAGGIPLTMADERLIVVPASYETDAGALQRLLSDFTTVVL
CCCCEEEEECCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
MKAGTALPAIVAALHQLNLIDHALYAERVGLAGEFITRDLRTLDLNHRPYLSLVIVRRGE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCEEEEEEECCC
LL
CC
>Mature Secondary Structure 
TDTPELIAVGLGPGDPELITVKGLRAIQAADVIFAPQSRDGDASIALQIATPWIDQSRQ
CCCCCEEEEECCCCCCCEEEECCCHHHHHCCEEECCCCCCCCCEEEEEEECCCCCCCCC
RIITLPLPMTRDSGQLRPAWQAAATVMQQEFGQHRRGVYLLLGDPLLYGTFVYLWRELRA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHH
AAPDITVSIIPGITSFAAAAAAGGIPLTMADERLIVVPASYETDAGALQRLLSDFTTVVL
CCCCEEEEECCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
MKAGTALPAIVAALHQLNLIDHALYAERVGLAGEFITRDLRTLDLNHRPYLSLVIVRRGE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCCCCEEEEEEECCC
LL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]