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The map label for this gene is cobB [H]

Identifier: 222526014

GI number: 222526014

Start: 3413910

End: 3415334

Strand: Reverse

Name: cobB [H]

Synonym: Chy400_2770

Alternate gene names: 222526014

Gene position: 3415334-3413910 (Counterclockwise)

Preceding gene: 222526015

Following gene: 222526013

Centisome position: 64.82

GC content: 62.18

Gene sequence:

>1425_bases
ATGCAGCTTCCCCGACTGTTGCTCGCCGCACCGATGAGCGGGAGCGGCAAAACGACGTTGACTGCCGGTTTGATTGGTGC
CCTCCGGCAACGCGGCTTGCGGATTGCACCCTTCAAGTGCGGCCCGGACTATATCGACCCCGGTTACCATGCGCTGGCTG
CTGAACGACCCTGCCACAACCTTGACTCCTGGCTGATGCCTGTCGATCAGATCGCCGGCATCCTGGCCCGCCGGAGTGGC
GATGCCGATCTGGCGCTCATCGAAGGCGTCATGGGTCTCTTCGACGGCTACGGTACCGACGATGACACCGGCAGTAGTGC
TCACATTGCCCGCTTGACGGCAACCCCGGTGATCATCGTGCTCGATGCCAGAGCGATGGCGCGCACGGCTGCCGCGCTGG
TTGCCGGTCTGCGCGACTTCGACCGCCGGCTGCATATCGGCGGGGTCATTTTGAATCGAGTCGGTAGCCCACGCCACGCT
ACCATCATTCAGACGGCCATTGAACAGACGATTGGGGTGCCGGTGTTGGGGTACCTTGAACGGGCTGAAGGGTTGACATT
ACCCGAACGCCATCTGGGGCTGGTGCCGGTGGCCGAGCCTGGGCATTGGCAAGAGTGGTTAACTGCGGTCACCAACCGAA
TTGCGGCTACCGTCGATCTTGATCGTCTGCTCGCGATTGCCCGTAGCGCTCCGCCCCTTACCATCCCGCCGCTCCCGACC
GTCACCGCAACCGATCAGAGCAACAGACCGGTCATCGCCGTGGCCCGCGACGAAGCCTTCAACTTTATCTATCCCGACAA
CCTCGACCTGCTGGAAGCTGCCGGTGCCCGCCTGGCCTTCTTCAGCCCCTTGCACGACAGGGCACTACCGGCAGCGACTG
CCGCGATCTACCTGTGTGGTGGGTTTCCCGAACTCTACGCTGCGCAACTGAGTGCGAACCAATCTCTGCGTGACGCGATA
CGTACCGCAGCCGCAAGCGGCATGCCGGTATACGCCGAGTGCGGCGGACTGATGTACCTGACCGAATCTCTGATCGATCA
GCACGGCCAGACCTTTCCAATGGTCGGTCTCTTGCCCGGTCACTCACGAATGACCCGCCGTCTGACCCTCGGCTACCGCA
CGGTCGTTGCCCAAACCGATACCTGGCTCTGGCACGCCGGCGAGACCATCCGCGGCCACGAGTTTCACTACTCGGTGTGG
GAAGAGCGTCCGCCAACTGTCACTCCCCTCTACACCTGTCTGCCCGACGCTTTGCGACCACAATCCGCAACGGAAGGCAT
TGTCAATGGTCAAACCCTGGCGTCGTACATTCATCTGCACTTTCTGAGCTGCCCACAGGCGGCGACGCGATTCGTGGCGG
CGGCAGGCCGGTATCAGACCGGCCAGAAGGAAGAGCGATATACCAACCGGGGAGATGCTGTATGA

Upstream 100 bases:

>100_bases
CAACCCTGCCCGATCTCCTGGCGACGCCATGCTGTGGGAAGAGTAGCGATACCGCACCCATTAGCCATGGATAACGAGCG
GAATAGACGGAGTACATGCG

Downstream 100 bases:

>100_bases
GTCAGATTGTTCTTTTCACCGGCGGCGCCCGCAGTGGCAAGAGTCGCTGTGCCGAACACTATGCGGCCCGGCTGAGCGAA
CAGATCGTCTACATCGCCAC

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MQLPRLLLAAPMSGSGKTTLTAGLIGALRQRGLRIAPFKCGPDYIDPGYHALAAERPCHNLDSWLMPVDQIAGILARRSG
DADLALIEGVMGLFDGYGTDDDTGSSAHIARLTATPVIIVLDARAMARTAAALVAGLRDFDRRLHIGGVILNRVGSPRHA
TIIQTAIEQTIGVPVLGYLERAEGLTLPERHLGLVPVAEPGHWQEWLTAVTNRIAATVDLDRLLAIARSAPPLTIPPLPT
VTATDQSNRPVIAVARDEAFNFIYPDNLDLLEAAGARLAFFSPLHDRALPAATAAIYLCGGFPELYAAQLSANQSLRDAI
RTAAASGMPVYAECGGLMYLTESLIDQHGQTFPMVGLLPGHSRMTRRLTLGYRTVVAQTDTWLWHAGETIRGHEFHYSVW
EERPPTVTPLYTCLPDALRPQSATEGIVNGQTLASYIHLHFLSCPQAATRFVAAAGRYQTGQKEERYTNRGDAV

Sequences:

>Translated_474_residues
MQLPRLLLAAPMSGSGKTTLTAGLIGALRQRGLRIAPFKCGPDYIDPGYHALAAERPCHNLDSWLMPVDQIAGILARRSG
DADLALIEGVMGLFDGYGTDDDTGSSAHIARLTATPVIIVLDARAMARTAAALVAGLRDFDRRLHIGGVILNRVGSPRHA
TIIQTAIEQTIGVPVLGYLERAEGLTLPERHLGLVPVAEPGHWQEWLTAVTNRIAATVDLDRLLAIARSAPPLTIPPLPT
VTATDQSNRPVIAVARDEAFNFIYPDNLDLLEAAGARLAFFSPLHDRALPAATAAIYLCGGFPELYAAQLSANQSLRDAI
RTAAASGMPVYAECGGLMYLTESLIDQHGQTFPMVGLLPGHSRMTRRLTLGYRTVVAQTDTWLWHAGETIRGHEFHYSVW
EERPPTVTPLYTCLPDALRPQSATEGIVNGQTLASYIHLHFLSCPQAATRFVAAAGRYQTGQKEERYTNRGDAV
>Mature_474_residues
MQLPRLLLAAPMSGSGKTTLTAGLIGALRQRGLRIAPFKCGPDYIDPGYHALAAERPCHNLDSWLMPVDQIAGILARRSG
DADLALIEGVMGLFDGYGTDDDTGSSAHIARLTATPVIIVLDARAMARTAAALVAGLRDFDRRLHIGGVILNRVGSPRHA
TIIQTAIEQTIGVPVLGYLERAEGLTLPERHLGLVPVAEPGHWQEWLTAVTNRIAATVDLDRLLAIARSAPPLTIPPLPT
VTATDQSNRPVIAVARDEAFNFIYPDNLDLLEAAGARLAFFSPLHDRALPAATAAIYLCGGFPELYAAQLSANQSLRDAI
RTAAASGMPVYAECGGLMYLTESLIDQHGQTFPMVGLLPGHSRMTRRLTLGYRTVVAQTDTWLWHAGETIRGHEFHYSVW
EERPPTVTPLYTCLPDALRPQSATEGIVNGQTLASYIHLHFLSCPQAATRFVAAAGRYQTGQKEERYTNRGDAV

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 51239; Mature: 51239

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPRLLLAAPMSGSGKTTLTAGLIGALRQRGLRIAPFKCGPDYIDPGYHALAAERPCHN
CCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHCCCCCCC
LDSWLMPVDQIAGILARRSGDADLALIEGVMGLFDGYGTDDDTGSSAHIARLTATPVIIV
HHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEE
LDARAMARTAAALVAGLRDFDRRLHIGGVILNRVGSPRHATIIQTAIEQTIGVPVLGYLE
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHH
RAEGLTLPERHLGLVPVAEPGHWQEWLTAVTNRIAATVDLDRLLAIARSAPPLTIPPLPT
HHCCCCCCHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VTATDQSNRPVIAVARDEAFNFIYPDNLDLLEAAGARLAFFSPLHDRALPAATAAIYLCG
EEECCCCCCCEEEEECCCCEEEECCCCCHHHHHCCCCEEEECCHHHHCCHHHHHEEEEEC
GFPELYAAQLSANQSLRDAIRTAAASGMPVYAECGGLMYLTESLIDQHGQTFPMVGLLPG
CCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCCCCEEEECCC
HSRMTRRLTLGYRTVVAQTDTWLWHAGETIRGHEFHYSVWEERPPTVTPLYTCLPDALRP
CHHHHHHHHHHHEEEEEECCCEEEECCCCCCCCEEEEEHHCCCCCCCCHHHHHCCHHCCC
QSATEGIVNGQTLASYIHLHFLSCPQAATRFVAAAGRYQTGQKEERYTNRGDAV
CCHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MQLPRLLLAAPMSGSGKTTLTAGLIGALRQRGLRIAPFKCGPDYIDPGYHALAAERPCHN
CCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHCCCCCCC
LDSWLMPVDQIAGILARRSGDADLALIEGVMGLFDGYGTDDDTGSSAHIARLTATPVIIV
HHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEE
LDARAMARTAAALVAGLRDFDRRLHIGGVILNRVGSPRHATIIQTAIEQTIGVPVLGYLE
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHH
RAEGLTLPERHLGLVPVAEPGHWQEWLTAVTNRIAATVDLDRLLAIARSAPPLTIPPLPT
HHCCCCCCHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VTATDQSNRPVIAVARDEAFNFIYPDNLDLLEAAGARLAFFSPLHDRALPAATAAIYLCG
EEECCCCCCCEEEEECCCCEEEECCCCCHHHHHCCCCEEEECCHHHHCCHHHHHEEEEEC
GFPELYAAQLSANQSLRDAIRTAAASGMPVYAECGGLMYLTESLIDQHGQTFPMVGLLPG
CCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCCCCEEEECCC
HSRMTRRLTLGYRTVVAQTDTWLWHAGETIRGHEFHYSVWEERPPTVTPLYTCLPDALRP
CHHHHHHHHHHHEEEEEECCCEEEECCCCCCCCEEEEEHHCCCCCCCCHHHHHCCHHCCC
QSATEGIVNGQTLASYIHLHFLSCPQAATRFVAAAGRYQTGQKEERYTNRGDAV
CCHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA