Click here to switch to the map view.

The map label for this gene is cobU [H]

Identifier: 222526013

GI number: 222526013

Start: 3413359

End: 3413913

Strand: Reverse

Name: cobU [H]

Synonym: Chy400_2769

Alternate gene names: 222526013

Gene position: 3413913-3413359 (Counterclockwise)

Preceding gene: 222526014

Following gene: 222526012

Centisome position: 64.79

GC content: 62.34

Gene sequence:

>555_bases
ATGAGTCAGATTGTTCTTTTCACCGGCGGCGCCCGCAGTGGCAAGAGTCGCTGTGCCGAACACTATGCGGCCCGGCTGAG
CGAACAGATCGTCTACATCGCCACTGCCACTGCCGGCGACGATGAAATGCGCGAACGGATTGCCCACCACCGTGCCCGTC
GCCCGGATACCTGGCACACCATCGAAGCCCCGACCGGCGTGGCCAGTGTGCTTACCGATCTCCCGCCCGGCACAGTCGTC
TTACTCGACTGCCTGGCGCTGCTGGTGAGTAACCTCTTGCTGGCCCACGAAGCGGCACCGGAACCGGCGATTGATGACGA
AATCACCGCGATGCTGGCCACCATTGCCAGCCGCAACCTCACCTTTGTTGCGGTCACGAACGAGGTCGGGATGGGGATTG
TGCCGGCGTACCCGCTTGGCCGGCATTATCGCGATCTCCTGGGTCGGGTCAATCAGCAGATCGCCGCCGCCGCCGCCGAA
GTCTATCTGGTGGTATGCGGCATACCAGTCGAATTACGCTCTCTGGAGGCAGCATGGATGCGTACAAACCGGTAG

Upstream 100 bases:

>100_bases
TTCTGAGCTGCCCACAGGCGGCGACGCGATTCGTGGCGGCGGCAGGCCGGTATCAGACCGGCCAGAAGGAAGAGCGATAT
ACCAACCGGGGAGATGCTGT

Downstream 100 bases:

>100_bases
TGCACGGTGCGCTCGACGAGGCTGAACTGGCCCGGCTTGGCCTGCGCGCCGACCATCTGATCGACTTCAGCAGCAACATC
AACCCCTTCGGGCCACCAGA

Product: adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSQIVLFTGGARSGKSRCAEHYAARLSEQIVYIATATAGDDEMRERIAHHRARRPDTWHTIEAPTGVASVLTDLPPGTVV
LLDCLALLVSNLLLAHEAAPEPAIDDEITAMLATIASRNLTFVAVTNEVGMGIVPAYPLGRHYRDLLGRVNQQIAAAAAE
VYLVVCGIPVELRSLEAAWMRTNR

Sequences:

>Translated_184_residues
MSQIVLFTGGARSGKSRCAEHYAARLSEQIVYIATATAGDDEMRERIAHHRARRPDTWHTIEAPTGVASVLTDLPPGTVV
LLDCLALLVSNLLLAHEAAPEPAIDDEITAMLATIASRNLTFVAVTNEVGMGIVPAYPLGRHYRDLLGRVNQQIAAAAAE
VYLVVCGIPVELRSLEAAWMRTNR
>Mature_183_residues
SQIVLFTGGARSGKSRCAEHYAARLSEQIVYIATATAGDDEMRERIAHHRARRPDTWHTIEAPTGVASVLTDLPPGTVVL
LDCLALLVSNLLLAHEAAPEPAIDDEITAMLATIASRNLTFVAVTNEVGMGIVPAYPLGRHYRDLLGRVNQQIAAAAAEV
YLVVCGIPVELRSLEAAWMRTNR

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=46.9613259668508, Blast_Score=150, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19910; Mature: 19779

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIVLFTGGARSGKSRCAEHYAARLSEQIVYIATATAGDDEMRERIAHHRARRPDTWHT
CCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEE
IEAPTGVASVLTDLPPGTVVLLDCLALLVSNLLLAHEAAPEPAIDDEITAMLATIASRNL
ECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCE
TFVAVTNEVGMGIVPAYPLGRHYRDLLGRVNQQIAAAAAEVYLVVCGIPVELRSLEAAWM
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHH
RTNR
HCCC
>Mature Secondary Structure 
SQIVLFTGGARSGKSRCAEHYAARLSEQIVYIATATAGDDEMRERIAHHRARRPDTWHT
CEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEE
IEAPTGVASVLTDLPPGTVVLLDCLALLVSNLLLAHEAAPEPAIDDEITAMLATIASRNL
ECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCE
TFVAVTNEVGMGIVPAYPLGRHYRDLLGRVNQQIAAAAAEVYLVVCGIPVELRSLEAAWM
EEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHH
RTNR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]