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The map label for this gene is argK [C]

Identifier: 222525948

GI number: 222525948

Start: 3335820

End: 3336956

Strand: Reverse

Name: argK [C]

Synonym: Chy400_2704

Alternate gene names: 222525948

Gene position: 3336956-3335820 (Counterclockwise)

Preceding gene: 222525949

Following gene: 222525939

Centisome position: 63.33

GC content: 62.27

Gene sequence:

>1137_bases
ATGACCGATAAGCAGCAGCCTTCATCTTCTGGCGAACTACCATTTGCGCTATCGGTACTGGCCGGGATTGCCAGCCGTCA
CGACGGCCTGCCCGGTAGCGCTCCGACGGTACCATCGGCACCTGCCGGAGTAGCCCGTCGCCAGTTGACGGTCGAGGAGT
ACGTAGCCGGTGTTCGCAATGGCGACCGGGCTATTCTGGCCCGTGCGATCACCCTCATCGAAAGTAACGCTCCGGCGCAT
ATGGCCCAGGCGCAGGCAGTATTGGCTGCGCTGCTACCGTACACCGGTGGTTCGCTGCGCGTTGGTATCACCGGCGTGCC
CGGCGTCGGCAAAAGCACCTTCATCGAAGCCCTCGGCACCATGCTCTGCGAGCGTGGGCATCGGGTGGCGGTACTGGCTA
TCGACCCTTCCAGCAGCATCTCACGTGGCAGTATCCTCGGTGATAAAACCCGTATGGAGCGGCTGGCCCGCCATCCCAAC
GCCTACATCCGACCTTCCCCCAGCGGTGGTAGCCTGGGTGGCGTGGCCCGCAAGAGTCGGGAAACGTTGCTGCTCTGCGA
GGCAGCCGGTTTCGATATCGTGCTGGTCGAGACGGTTGGAGTTGGTCAGAGTGAAACCGCTGTACGTGGGATGGTTGATT
TCTTTCTATTGCTGATGCTGGCCGGTGCCGGCGATGAACTGCAAGGGATCAAGAAGGGGGTGATCGAGCTGGCCGATGCG
CTGGTGATCACCAAGGCCGATGGCGATAACCGGGCACGCGCAATGGCAGCCCAGGCCGAGTACCGGCATGCATTGCGTTA
CCTGACCCCGGCCACACCGGGCTGGAAACCGCCGGTACGCACCTGCTCGGCGCTTACCGGCAGTGGCATTGCCGAAATCT
GGCAGGAGATCGAGCGTTTTCGCGCTGAGATGACGGCGAGTGGTGTCTTTGCGGCACGCCGTCGGGAACAGGCTCGCGAC
TGGCTCTACACCCTGATCGACGAACAGTTGCGCACCCTCTTCTTTGCGCATCCCGCGGTACGTGACCGACTACCGGCCCT
CGAACAGGCAGTAGTCGAAGGAACAGTGCCGGTCGTCAGTGCCGTTCAGCAGCTCTTCGCGGCACTTGGCGAAACCCAAC
CCCAACCAACACCGTAA

Upstream 100 bases:

>100_bases
ATTCCGGTCGCTGCCGAGAAGCTGTTGCGCGAGTTGCAACGGCGTCTCCACGGTGATAGCGTCGCTGCACCGGCATCGTG
AAACGAGGGTGAGAGGGATC

Downstream 100 bases:

>100_bases
CAGAGACGCGAAGGGCGAATGGCCCTTCGCGTCTCCTAAACGATCAGGTATCTTCGCGGAGAATGTACCCCACACTGCGA
ACAGTATGGATCAGGCGCGG

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTDKQQPSSSGELPFALSVLAGIASRHDGLPGSAPTVPSAPAGVARRQLTVEEYVAGVRNGDRAILARAITLIESNAPAH
MAQAQAVLAALLPYTGGSLRVGITGVPGVGKSTFIEALGTMLCERGHRVAVLAIDPSSSISRGSILGDKTRMERLARHPN
AYIRPSPSGGSLGGVARKSRETLLLCEAAGFDIVLVETVGVGQSETAVRGMVDFFLLLMLAGAGDELQGIKKGVIELADA
LVITKADGDNRARAMAAQAEYRHALRYLTPATPGWKPPVRTCSALTGSGIAEIWQEIERFRAEMTASGVFAARRREQARD
WLYTLIDEQLRTLFFAHPAVRDRLPALEQAVVEGTVPVVSAVQQLFAALGETQPQPTP

Sequences:

>Translated_378_residues
MTDKQQPSSSGELPFALSVLAGIASRHDGLPGSAPTVPSAPAGVARRQLTVEEYVAGVRNGDRAILARAITLIESNAPAH
MAQAQAVLAALLPYTGGSLRVGITGVPGVGKSTFIEALGTMLCERGHRVAVLAIDPSSSISRGSILGDKTRMERLARHPN
AYIRPSPSGGSLGGVARKSRETLLLCEAAGFDIVLVETVGVGQSETAVRGMVDFFLLLMLAGAGDELQGIKKGVIELADA
LVITKADGDNRARAMAAQAEYRHALRYLTPATPGWKPPVRTCSALTGSGIAEIWQEIERFRAEMTASGVFAARRREQARD
WLYTLIDEQLRTLFFAHPAVRDRLPALEQAVVEGTVPVVSAVQQLFAALGETQPQPTP
>Mature_377_residues
TDKQQPSSSGELPFALSVLAGIASRHDGLPGSAPTVPSAPAGVARRQLTVEEYVAGVRNGDRAILARAITLIESNAPAHM
AQAQAVLAALLPYTGGSLRVGITGVPGVGKSTFIEALGTMLCERGHRVAVLAIDPSSSISRGSILGDKTRMERLARHPNA
YIRPSPSGGSLGGVARKSRETLLLCEAAGFDIVLVETVGVGQSETAVRGMVDFFLLLMLAGAGDELQGIKKGVIELADAL
VITKADGDNRARAMAAQAEYRHALRYLTPATPGWKPPVRTCSALTGSGIAEIWQEIERFRAEMTASGVFAARRREQARDW
LYTLIDEQLRTLFFAHPAVRDRLPALEQAVVEGTVPVVSAVQQLFAALGETQPQPTP

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=321, Percent_Identity=50.1557632398754, Blast_Score=308, Evalue=5e-84,
Organism=Escherichia coli, GI1789285, Length=288, Percent_Identity=51.7361111111111, Blast_Score=300, Evalue=8e-83,
Organism=Caenorhabditis elegans, GI71994271, Length=318, Percent_Identity=44.0251572327044, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71994275, Length=259, Percent_Identity=47.1042471042471, Blast_Score=257, Evalue=8e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 40058; Mature: 39927

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKQQPSSSGELPFALSVLAGIASRHDGLPGSAPTVPSAPAGVARRQLTVEEYVAGVRN
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
GDRAILARAITLIESNAPAHMAQAQAVLAALLPYTGGSLRVGITGVPGVGKSTFIEALGT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHH
MLCERGHRVAVLAIDPSSSISRGSILGDKTRMERLARHPNAYIRPSPSGGSLGGVARKSR
HHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCHHHHCCC
ETLLLCEAAGFDIVLVETVGVGQSETAVRGMVDFFLLLMLAGAGDELQGIKKGVIELADA
CEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LVITKADGDNRARAMAAQAEYRHALRYLTPATPGWKPPVRTCSALTGSGIAEIWQEIERF
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
RAEMTASGVFAARRREQARDWLYTLIDEQLRTLFFAHPAVRDRLPALEQAVVEGTVPVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHH
AVQQLFAALGETQPQPTP
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDKQQPSSSGELPFALSVLAGIASRHDGLPGSAPTVPSAPAGVARRQLTVEEYVAGVRN
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
GDRAILARAITLIESNAPAHMAQAQAVLAALLPYTGGSLRVGITGVPGVGKSTFIEALGT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHH
MLCERGHRVAVLAIDPSSSISRGSILGDKTRMERLARHPNAYIRPSPSGGSLGGVARKSR
HHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCHHHHCCC
ETLLLCEAAGFDIVLVETVGVGQSETAVRGMVDFFLLLMLAGAGDELQGIKKGVIELADA
CEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LVITKADGDNRARAMAAQAEYRHALRYLTPATPGWKPPVRTCSALTGSGIAEIWQEIERF
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
RAEMTASGVFAARRREQARDWLYTLIDEQLRTLFFAHPAVRDRLPALEQAVVEGTVPVVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHH
AVQQLFAALGETQPQPTP
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]