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The map label for this gene is aroF [H]

Identifier: 222525651

GI number: 222525651

Start: 3028836

End: 3029852

Strand: Direct

Name: aroF [H]

Synonym: Chy400_2402

Alternate gene names: 222525651

Gene position: 3028836-3029852 (Clockwise)

Preceding gene: 222525650

Following gene: 222525652

Centisome position: 57.48

GC content: 57.33

Gene sequence:

>1017_bases
ATGATTGTCGTCATGCAAACCGACTCAACCCCTGGACAGATTGAAGCGGTGTTAAACCGGCTGCGCGAACACAATTTGCG
CGGCCATCTGACCGTTGGTGAGGAGCGCACGGTGATCGCGGTGGTGGGGGCAGCGATCCCGCCAACCTTGCGGGAAGAGC
TAGAACACTTTGCCGGTGTGAAGGAGACCCTGCGCATCACGCAACCCTACAAGCTGGTATCCCGTGAGGTAAAGCCCAGC
GATACGGTGGTGACGGTTGGTGATGTAAAGGTTGGCGGTGGGCACCTGGCAATTATTGCCGGCCCGTGCTCGGTTGAGAG
TGAAGAGCAGATTATGGCGACCGCCCGTGCAGTACGCGAGGCTGGGGCGAACATGTTGCGCGGTGGTGCGTTCAAGCCTC
GCTCATCGCCTTACAGTTTCCGTGGCCTGGGTGAGGTTGGTTTACAGTTGCTGGCGCAGGCACGTGCCGAGACGGGATTG
CCAATTGTGACCGAAGTTATGACTCCGGCTGACGTTGATCTGGTTGCCCGCTATGCCGATGTCTTGCAGATCGGCGCCCG
CAACATGCAGAATTATCAGTTGCTGGAAGAGGTCGGGCGTACCGGCATGCCGGTGCTGCTCAAGCGCGGTTTATCGGCTA
CGATTGAAGAGTGGTTGTTGTCGGCTGAGTACATTATTGCCCAGGGTAATCCAAATGTGATTCTGTGTGAGCGCGGAATC
CGCACGTTCGAGACGGCGACCCGCAATACCCTCGATCTGAATGCAGTAGCCGTAGCCAGGAAGCGCTCACATCTACCGGT
AATTGTTGATCCGAGTCACGGTACCGGGAAGTGGTATCTGGTTCCACCATTAACCCTGGCTGCAATTGCCGCCGGTGCTG
ATGGTGTGATCATTGAAGTTCACCCCGATCCTGATCGGGCAAAGTCGGACGGCGGCCAGTCACTGAACCCAGAGAACTTC
ATGGGCCTGGTGCCCCAAATGCGAGCCATCGCGAAAGTTGTTGGCAAGACCTGGTAA

Upstream 100 bases:

>100_bases
CATGAGTCGTCGTCAAGACCCTGCCGGACACGCAGCGTTGCGTGTTGTGCCCGTTTTGTCTACCGATGCCTGTTCTTGTA
TGCCTGAGGAGGACCGTTCC

Downstream 100 bases:

>100_bases
TTACCACGCATGTCAGGAGCGCACAACGAAGTGCTCTCCTCCCCGGCATAGCTGCCCAAACGCCGCACAATGACTGTGCT
CCTCGTAAAATACGGTGATC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIVVMQTDSTPGQIEAVLNRLREHNLRGHLTVGEERTVIAVVGAAIPPTLREELEHFAGVKETLRITQPYKLVSREVKPS
DTVVTVGDVKVGGGHLAIIAGPCSVESEEQIMATARAVREAGANMLRGGAFKPRSSPYSFRGLGEVGLQLLAQARAETGL
PIVTEVMTPADVDLVARYADVLQIGARNMQNYQLLEEVGRTGMPVLLKRGLSATIEEWLLSAEYIIAQGNPNVILCERGI
RTFETATRNTLDLNAVAVARKRSHLPVIVDPSHGTGKWYLVPPLTLAAIAAGADGVIIEVHPDPDRAKSDGGQSLNPENF
MGLVPQMRAIAKVVGKTW

Sequences:

>Translated_338_residues
MIVVMQTDSTPGQIEAVLNRLREHNLRGHLTVGEERTVIAVVGAAIPPTLREELEHFAGVKETLRITQPYKLVSREVKPS
DTVVTVGDVKVGGGHLAIIAGPCSVESEEQIMATARAVREAGANMLRGGAFKPRSSPYSFRGLGEVGLQLLAQARAETGL
PIVTEVMTPADVDLVARYADVLQIGARNMQNYQLLEEVGRTGMPVLLKRGLSATIEEWLLSAEYIIAQGNPNVILCERGI
RTFETATRNTLDLNAVAVARKRSHLPVIVDPSHGTGKWYLVPPLTLAAIAAGADGVIIEVHPDPDRAKSDGGQSLNPENF
MGLVPQMRAIAKVVGKTW
>Mature_338_residues
MIVVMQTDSTPGQIEAVLNRLREHNLRGHLTVGEERTVIAVVGAAIPPTLREELEHFAGVKETLRITQPYKLVSREVKPS
DTVVTVGDVKVGGGHLAIIAGPCSVESEEQIMATARAVREAGANMLRGGAFKPRSSPYSFRGLGEVGLQLLAQARAETGL
PIVTEVMTPADVDLVARYADVLQIGARNMQNYQLLEEVGRTGMPVLLKRGLSATIEEWLLSAEYIIAQGNPNVILCERGI
RTFETATRNTLDLNAVAVARKRSHLPVIVDPSHGTGKWYLVPPLTLAAIAAGADGVIIEVHPDPDRAKSDGGQSLNPENF
MGLVPQMRAIAKVVGKTW

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=272, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36408; Mature: 36408

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVMQTDSTPGQIEAVLNRLREHNLRGHLTVGEERTVIAVVGAAIPPTLREELEHFAGV
CEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCH
KETLRITQPYKLVSREVKPSDTVVTVGDVKVGGGHLAIIAGPCSVESEEQIMATARAVRE
HHHHCCCCCHHHHHCCCCCCCCEEEECCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHH
AGANMLRGGAFKPRSSPYSFRGLGEVGLQLLAQARAETGLPIVTEVMTPADVDLVARYAD
HCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHH
VLQIGARNMQNYQLLEEVGRTGMPVLLKRGLSATIEEWLLSAEYIIAQGNPNVILCERGI
HHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCEEEEECCCCCEEEECCCC
RTFETATRNTLDLNAVAVARKRSHLPVIVDPSHGTGKWYLVPPLTLAAIAAGADGVIIEV
HHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCEEEEECCHHHHHHHCCCCEEEEEE
HPDPDRAKSDGGQSLNPENFMGLVPQMRAIAKVVGKTW
CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIVVMQTDSTPGQIEAVLNRLREHNLRGHLTVGEERTVIAVVGAAIPPTLREELEHFAGV
CEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCH
KETLRITQPYKLVSREVKPSDTVVTVGDVKVGGGHLAIIAGPCSVESEEQIMATARAVRE
HHHHCCCCCHHHHHCCCCCCCCEEEECCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHH
AGANMLRGGAFKPRSSPYSFRGLGEVGLQLLAQARAETGLPIVTEVMTPADVDLVARYAD
HCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHH
VLQIGARNMQNYQLLEEVGRTGMPVLLKRGLSATIEEWLLSAEYIIAQGNPNVILCERGI
HHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCEEEEECCCCCEEEECCCC
RTFETATRNTLDLNAVAVARKRSHLPVIVDPSHGTGKWYLVPPLTLAAIAAGADGVIIEV
HHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCEEEEECCHHHHHHHCCCCEEEEEE
HPDPDRAKSDGGQSLNPENFMGLVPQMRAIAKVVGKTW
CCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]