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The map label for this gene is yhcW [H]

Identifier: 222525563

GI number: 222525563

Start: 2925398

End: 2926081

Strand: Reverse

Name: yhcW [H]

Synonym: Chy400_2312

Alternate gene names: 222525563

Gene position: 2926081-2925398 (Counterclockwise)

Preceding gene: 222525566

Following gene: 222525548

Centisome position: 55.53

GC content: 60.67

Gene sequence:

>684_bases
ATGCCGATCCATGCCCTCATCTTCGACTTCGACGGCCTGATGGTCGATACCGAGACACCCGCCTTACAAAGCTGGCAAGA
GATCTATGCCGAATATGGTGTTACCCTAAGCGTCCACGATTGGGCGATCACCCTTGGCGCAAACGCCGGATTTGATGCTC
ATGCCCATCTCGTCGCGTTACTCCGGCAACGCGATCCCCAATTGGCCGAACAAGTCATTGCGGCACGCGATACGATCCTC
GCTCGCCGACAGGCCCGCAAGGATGAACTAAGCGCGCCACAAACGCTTCTGCCCGGTGTTGCTGAGTTGCTAGCCGAAGC
ACACTCAAAGGGCTTACCCTGTGCAGTTGCCAGTAGCAGTAGCCGGCGCTGGGTTGAAGGCTGGCTTGAACGTCTAGGCA
TACGCCCCTTCTTCGCAACAGTCGTCACGGCTGATGATGTAGCAGCAACAAAACCGGCACCCGATCTCTTCCTGGAAGCA
GCTCGCCGCCTGGGTCTGCCGCCAGCAACCTGCCTGGTACTCGAAGACTCCCCCAACGGCATCCGGGCTGCCCGGGCAGC
CGGCTGCCCGGTCGTCGCCATCCCCGGCGCGATCTCCGGGCAGGTTCCGCTACCGCCTGCCGACCTGACATTGCCCAGCC
TGGCCCACACCACACTTGCCGACTTACAAGCTATCTTTCGCTAG

Upstream 100 bases:

>100_bases
ACACGAGCTTGCATGAAACAGCACGCACATCAACTCAAGTACAATGAGTGTGGAATCTATACATTGGCAGCAACGGATCG
CTGATGCAAAGGAGACCTGA

Downstream 100 bases:

>100_bases
CGATGCCCGAAACCATTCCGCACATCCACAGCGCAATCACGTGCTGGATTGGTTAGCTTTCACCGGCAAGGATTCACGTG
TCGCGTGGGGTCGAAAGGGT

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPIHALIFDFDGLMVDTETPALQSWQEIYAEYGVTLSVHDWAITLGANAGFDAHAHLVALLRQRDPQLAEQVIAARDTIL
ARRQARKDELSAPQTLLPGVAELLAEAHSKGLPCAVASSSSRRWVEGWLERLGIRPFFATVVTADDVAATKPAPDLFLEA
ARRLGLPPATCLVLEDSPNGIRAARAAGCPVVAIPGAISGQVPLPPADLTLPSLAHTTLADLQAIFR

Sequences:

>Translated_227_residues
MPIHALIFDFDGLMVDTETPALQSWQEIYAEYGVTLSVHDWAITLGANAGFDAHAHLVALLRQRDPQLAEQVIAARDTIL
ARRQARKDELSAPQTLLPGVAELLAEAHSKGLPCAVASSSSRRWVEGWLERLGIRPFFATVVTADDVAATKPAPDLFLEA
ARRLGLPPATCLVLEDSPNGIRAARAAGCPVVAIPGAISGQVPLPPADLTLPSLAHTTLADLQAIFR
>Mature_226_residues
PIHALIFDFDGLMVDTETPALQSWQEIYAEYGVTLSVHDWAITLGANAGFDAHAHLVALLRQRDPQLAEQVIAARDTILA
RRQARKDELSAPQTLLPGVAELLAEAHSKGLPCAVASSSSRRWVEGWLERLGIRPFFATVVTADDVAATKPAPDLFLEAA
RRLGLPPATCLVLEDSPNGIRAARAAGCPVVAIPGAISGQVPLPPADLTLPSLAHTTLADLQAIFR

Specific function: Unknown

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=199, Percent_Identity=33.1658291457286, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI207113149, Length=252, Percent_Identity=29.7619047619048, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI296011030, Length=199, Percent_Identity=29.6482412060301, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI296011028, Length=191, Percent_Identity=28.2722513089005, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1789046, Length=196, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787576, Length=218, Percent_Identity=30.7339449541284, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788021, Length=223, Percent_Identity=32.2869955156951, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789787, Length=128, Percent_Identity=37.5, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082080, Length=219, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129151, Length=222, Percent_Identity=31.0810810810811, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17137324, Length=223, Percent_Identity=34.0807174887892, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116008157, Length=217, Percent_Identity=33.6405529953917, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24244; Mature: 24113

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIHALIFDFDGLMVDTETPALQSWQEIYAEYGVTLSVHDWAITLGANAGFDAHAHLVAL
CCCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCCCHHHHHHHH
LRQRDPQLAEQVIAARDTILARRQARKDELSAPQTLLPGVAELLAEAHSKGLPCAVASSS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCC
SRRWVEGWLERLGIRPFFATVVTADDVAATKPAPDLFLEAARRLGLPPATCLVLEDSPNG
CCHHHHHHHHHHCCCHHHHHEEECCCHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCC
IRAARAAGCPVVAIPGAISGQVPLPPADLTLPSLAHTTLADLQAIFR
HHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PIHALIFDFDGLMVDTETPALQSWQEIYAEYGVTLSVHDWAITLGANAGFDAHAHLVAL
CCEEEEEECCCEEEECCCHHHHHHHHHHHHHCCEEEEEEEEEEECCCCCCCHHHHHHHH
LRQRDPQLAEQVIAARDTILARRQARKDELSAPQTLLPGVAELLAEAHSKGLPCAVASSS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCC
SRRWVEGWLERLGIRPFFATVVTADDVAATKPAPDLFLEAARRLGLPPATCLVLEDSPNG
CCHHHHHHHHHHCCCHHHHHEEECCCHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCC
IRAARAAGCPVVAIPGAISGQVPLPPADLTLPSLAHTTLADLQAIFR
HHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]