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The map label for this gene is ctaD [H]

Identifier: 222525559

GI number: 222525559

Start: 2921425

End: 2923083

Strand: Direct

Name: ctaD [H]

Synonym: Chy400_2308

Alternate gene names: 222525559

Gene position: 2921425-2923083 (Clockwise)

Preceding gene: 222525558

Following gene: 222525560

Centisome position: 55.45

GC content: 54.31

Gene sequence:

>1659_bases
ATGAGCACGCTTTCTCTTCCACAGACGAGCTATATTCACGATCATTCGCGAACGTTTATTGATTGGCTCAAGTCGTGGTT
GCTGACGGTTGATCACAAGCGGATCGCAATACTCTACCTGTTGGCGATTAACTTCTTCTTCCTGCTCGGTGGCCTGGCTG
CTACTGTGGTACGGATTGAGTTGATCACCCCGCAGGGCGATCTGATGTCGTCGGATGTCTACAACCGGGCTTTCACGCTG
CACGGCGTGATCATGGTCTTCTTCTTCCTGATCCCGTCGATTCCGGCGGTGCTGGGTAATTTCCTGGTGCCGTTGATGAT
CGGTGCCCGTGACCTGGCATTCCCACGGTTGAATCTGTTGAGCTGGTATCTCTACATGATCGGTGGTATCTTCGCCCTGA
TCGCAGCCGTCTTCGGCGGTGTTGATACCGGCTGGACGTTCTACACTCCCTTCAGCTCAACCTATTCCAACTCGAACGTG
GTGATGACGATTACCGGTGCGTTTATTATGGGGTTTTCCTCCATCTTGACCGGTCTTAATTTCATCGTCACCATCCACAA
GATGCGGGCACCTGGTTTGACCTGGTTCCGTTTGCCACTCTTCATCTGGGCGAACTATGCAACCAGTATCATTCAGATTC
TGGCAACACCGGTATTGGGTATCGCGCTGCTGCTGGTGATCGTCGAGCGGGTTTGGGGTGTCGGTATCTACGATCCGGCG
CTGGGTGGTGATCCACTCCTCTTCCAGCACCTCTTCTGGTTCTACTCGCATCCGGCAGTCTACATCATGATTTTGCCGGC
AATGGGTGTGGTCAGCGAGTTGATCAGCACCTTCTCGCGCAAGCGAATCTTCGGCTACGAGTTCATTGCCTTTTCGAGTA
TTGCCATCGCTATCCTGGGCTTTCTGGTCTGGGGGCACCACATGTTCGTGAGCAGCCAGTCGGTGTACGCGGGGCTGATC
TTCTCGTTTATCACTATGCTGGTTGCAATCCCGTCAGCGATTAAGGTCTTTAACTGGACGGCAACGCTCTACAAGGGTTC
AATCAGCTATCGCACGCCGATGCTGTACGCGCTCGGTTTTATCGGTCTGTTCGTGATCGGTGGTCTGACCGGTATCTTCC
TCGGTGTGGTAGCGGTTGACCTGCACGTGACCGATACCTACTTCGTGGTCGCTCACTTCCACTACGTGATGGTGGGTGGT
ACGATTATGGCCTATCTGGGTGGCATTCACTTCTGGTGGCCGAAGATGACTGGTCGCATGTACAACGAGACCTGGGGCAG
CATTGCGGCACTGATCATCTTCGTTGGCTTTAATATGACCTTCTTCCCCCAGTTTATTCTCGGCTACCTGGGTATGCCAC
GGCGCTATCACGTCTATCCGCCGGAGTTCCAGATTTTGCACGTGATGAGCACGGCTGGTGCCAGCATTCTGGCGATTGGC
TTCATCGTGCCTCTTATCTATCTGGGTATCTCGCTGTGGAAGGGGCGGATTGCCGGTGACAACCCGTGGGGAGCGACCGG
TCTGGAATGGAAGACTTCATCACCACCACCAACCCACAATTTCGATAAGACGCCGATTGTGACCGAAGAGGCGTATGCGT
ATCCGCCGGAAGCTGCCGAGCGTGATGCGGCGTCCTGGCGACCGGGTTCACCACTATAA

Upstream 100 bases:

>100_bases
TCCTGCGGTTATGCCATCGTATCAGGGGCAGATCAGCGAGGATCAGCTTAACCAATTGATTGCGTATATTAAGTCACTCG
CCGACACGGGGAATTAGTCT

Downstream 100 bases:

>100_bases
GGCTGGTGGTACTGATAGCAGAACACCAGGTACAAGATTGTCGGTAGTGGCGTTGATAGGTAAAGGCAGAGGAGAGAGCG
TTGGCAACGATCACTCACGA

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MSTLSLPQTSYIHDHSRTFIDWLKSWLLTVDHKRIAILYLLAINFFFLLGGLAATVVRIELITPQGDLMSSDVYNRAFTL
HGVIMVFFFLIPSIPAVLGNFLVPLMIGARDLAFPRLNLLSWYLYMIGGIFALIAAVFGGVDTGWTFYTPFSSTYSNSNV
VMTITGAFIMGFSSILTGLNFIVTIHKMRAPGLTWFRLPLFIWANYATSIIQILATPVLGIALLLVIVERVWGVGIYDPA
LGGDPLLFQHLFWFYSHPAVYIMILPAMGVVSELISTFSRKRIFGYEFIAFSSIAIAILGFLVWGHHMFVSSQSVYAGLI
FSFITMLVAIPSAIKVFNWTATLYKGSISYRTPMLYALGFIGLFVIGGLTGIFLGVVAVDLHVTDTYFVVAHFHYVMVGG
TIMAYLGGIHFWWPKMTGRMYNETWGSIAALIIFVGFNMTFFPQFILGYLGMPRRYHVYPPEFQILHVMSTAGASILAIG
FIVPLIYLGISLWKGRIAGDNPWGATGLEWKTSSPPPTHNFDKTPIVTEEAYAYPPEAAERDAASWRPGSPL

Sequences:

>Translated_552_residues
MSTLSLPQTSYIHDHSRTFIDWLKSWLLTVDHKRIAILYLLAINFFFLLGGLAATVVRIELITPQGDLMSSDVYNRAFTL
HGVIMVFFFLIPSIPAVLGNFLVPLMIGARDLAFPRLNLLSWYLYMIGGIFALIAAVFGGVDTGWTFYTPFSSTYSNSNV
VMTITGAFIMGFSSILTGLNFIVTIHKMRAPGLTWFRLPLFIWANYATSIIQILATPVLGIALLLVIVERVWGVGIYDPA
LGGDPLLFQHLFWFYSHPAVYIMILPAMGVVSELISTFSRKRIFGYEFIAFSSIAIAILGFLVWGHHMFVSSQSVYAGLI
FSFITMLVAIPSAIKVFNWTATLYKGSISYRTPMLYALGFIGLFVIGGLTGIFLGVVAVDLHVTDTYFVVAHFHYVMVGG
TIMAYLGGIHFWWPKMTGRMYNETWGSIAALIIFVGFNMTFFPQFILGYLGMPRRYHVYPPEFQILHVMSTAGASILAIG
FIVPLIYLGISLWKGRIAGDNPWGATGLEWKTSSPPPTHNFDKTPIVTEEAYAYPPEAAERDAASWRPGSPL
>Mature_551_residues
STLSLPQTSYIHDHSRTFIDWLKSWLLTVDHKRIAILYLLAINFFFLLGGLAATVVRIELITPQGDLMSSDVYNRAFTLH
GVIMVFFFLIPSIPAVLGNFLVPLMIGARDLAFPRLNLLSWYLYMIGGIFALIAAVFGGVDTGWTFYTPFSSTYSNSNVV
MTITGAFIMGFSSILTGLNFIVTIHKMRAPGLTWFRLPLFIWANYATSIIQILATPVLGIALLLVIVERVWGVGIYDPAL
GGDPLLFQHLFWFYSHPAVYIMILPAMGVVSELISTFSRKRIFGYEFIAFSSIAIAILGFLVWGHHMFVSSQSVYAGLIF
SFITMLVAIPSAIKVFNWTATLYKGSISYRTPMLYALGFIGLFVIGGLTGIFLGVVAVDLHVTDTYFVVAHFHYVMVGGT
IMAYLGGIHFWWPKMTGRMYNETWGSIAALIIFVGFNMTFFPQFILGYLGMPRRYHVYPPEFQILHVMSTAGASILAIGF
IVPLIYLGISLWKGRIAGDNPWGATGLEWKTSSPPPTHNFDKTPIVTEEAYAYPPEAAERDAASWRPGSPL

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=506, Percent_Identity=39.9209486166008, Blast_Score=359, Evalue=4e-99,
Organism=Escherichia coli, GI1786634, Length=535, Percent_Identity=37.196261682243, Blast_Score=364, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6226519, Length=536, Percent_Identity=36.5671641791045, Blast_Score=334, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=37.6543209876543, Blast_Score=223, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=34.9397590361446, Blast_Score=134, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61486; Mature: 61355

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLSLPQTSYIHDHSRTFIDWLKSWLLTVDHKRIAILYLLAINFFFLLGGLAATVVRIE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LITPQGDLMSSDVYNRAFTLHGVIMVFFFLIPSIPAVLGNFLVPLMIGARDLAFPRLNLL
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
SWYLYMIGGIFALIAAVFGGVDTGWTFYTPFSSTYSNSNVVMTITGAFIMGFSSILTGLN
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
FIVTIHKMRAPGLTWFRLPLFIWANYATSIIQILATPVLGIALLLVIVERVWGVGIYDPA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LGGDPLLFQHLFWFYSHPAVYIMILPAMGVVSELISTFSRKRIFGYEFIAFSSIAIAILG
CCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FLVWGHHMFVSSQSVYAGLIFSFITMLVAIPSAIKVFNWTATLYKGSISYRTPMLYALGF
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEECCCCCCCHHHHHHHH
IGLFVIGGLTGIFLGVVAVDLHVTDTYFVVAHFHYVMVGGTIMAYLGGIHFWWPKMTGRM
HHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCHHEECHHHCCCH
YNETWGSIAALIIFVGFNMTFFPQFILGYLGMPRRYHVYPPEFQILHVMSTAGASILAIG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEHHHCCHHHHHHH
FIVPLIYLGISLWKGRIAGDNPWGATGLEWKTSSPPPTHNFDKTPIVTEEAYAYPPEAAE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
RDAASWRPGSPL
CCCCCCCCCCCC
>Mature Secondary Structure 
STLSLPQTSYIHDHSRTFIDWLKSWLLTVDHKRIAILYLLAINFFFLLGGLAATVVRIE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEE
LITPQGDLMSSDVYNRAFTLHGVIMVFFFLIPSIPAVLGNFLVPLMIGARDLAFPRLNLL
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
SWYLYMIGGIFALIAAVFGGVDTGWTFYTPFSSTYSNSNVVMTITGAFIMGFSSILTGLN
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
FIVTIHKMRAPGLTWFRLPLFIWANYATSIIQILATPVLGIALLLVIVERVWGVGIYDPA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LGGDPLLFQHLFWFYSHPAVYIMILPAMGVVSELISTFSRKRIFGYEFIAFSSIAIAILG
CCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
FLVWGHHMFVSSQSVYAGLIFSFITMLVAIPSAIKVFNWTATLYKGSISYRTPMLYALGF
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEECCCCCCCHHHHHHHH
IGLFVIGGLTGIFLGVVAVDLHVTDTYFVVAHFHYVMVGGTIMAYLGGIHFWWPKMTGRM
HHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCHHEECHHHCCCH
YNETWGSIAALIIFVGFNMTFFPQFILGYLGMPRRYHVYPPEFQILHVMSTAGASILAIG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEHHHCCHHHHHHH
FIVPLIYLGISLWKGRIAGDNPWGATGLEWKTSSPPPTHNFDKTPIVTEEAYAYPPEAAE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
RDAASWRPGSPL
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8399373 [H]