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The map label for this gene is ctaC [H]

Identifier: 222525558

GI number: 222525558

Start: 2920429

End: 2921421

Strand: Direct

Name: ctaC [H]

Synonym: Chy400_2307

Alternate gene names: 222525558

Gene position: 2920429-2921421 (Clockwise)

Preceding gene: 222525557

Following gene: 222525559

Centisome position: 55.43

GC content: 52.67

Gene sequence:

>993_bases
ATGCGCGATTTTCCGTTATTTCCCGATCAGGCATCAACCTTTGCAACCCAGGTTGATCAGCTCTACTTTTTTCTGGTGGC
CCTGAGCCTCATTTTTGCCGGGGTGTTACCGTTTGTTATTCTCTATCTGATCGTTCGTTATCACCGTAGTCAGAAGGTTG
ATCGGAGTAATCCGGTTGACTCCAACCTTAAACTAGAGCTGACCTGGACGATAATCCCGTTAATACTGGTCATGCTGGTC
TTCTTCTGGGGTGCGTTTTTGTACGTACAGATGCGAACTCCACCGGCGCGCACTCTGGATGTCTATGTGATCGGCAAGCA
ATGGATGTGGCACGTGCAGCATCCAAACGGTAAGCGCGAGAATAATGAGCTGCACGTTCCAATTGGCCAGCCCGTGAAGC
TGATAATGACATCGCAAGATGTGATTCATAGCTTCTACATTCCGGCGTTCCGCGTGAAGCAAGATGTGTTGCCGGGCCGC
TACACAATCATGTGGTTCGAGGCGACCAAACCCGGTGAGTATCATCTGTTCTGCGCCGAGTACTGTGGTACTGAACATTC
GCTGATGATTGGTCGGGTTGTCGCCATGCCGTTGGCCGATTACGAGCGCTGGCTGGCAACTCCTGGGCCGGTAGTGTTAC
CTGATGGTTCGATTGATACGGGCCAGCCGACGATAACTGCAAATCTCGGCGATCCAATGGCTGCGGCGGGTAGTCAACTC
TTCACAAGCCTGGGTTGTGCCGGCTGCCACGCAATGGCCGGTGGTGGCGTTGGACCGAGCATGCAGGGTTTGTACGGAGC
AACAGAGAAAATGGCTGATGGCTCGACAGTCACGGCTGATGAGAACTATCTGCGTGAGTCGATCCTCAATCCGAATGCGA
AGATTGTGGCCGGCTATCCTGCGGTTATGCCATCGTATCAGGGGCAGATCAGCGAGGATCAGCTTAACCAATTGATTGCG
TATATTAAGTCACTCGCCGACACGGGGAATTAG

Upstream 100 bases:

>100_bases
CGTTCAACACCCGGCGGTAATTTGCCGCCACCACGTGAATCGGTGCCGGCTTAGTGGTAGTTGCGACTGGGGCGGCAATG
CCCCCGGACAGGACGAAGGT

Downstream 100 bases:

>100_bases
TCTATGAGCACGCTTTCTCTTCCACAGACGAGCTATATTCACGATCATTCGCGAACGTTTATTGATTGGCTCAAGTCGTG
GTTGCTGACGGTTGATCACA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MRDFPLFPDQASTFATQVDQLYFFLVALSLIFAGVLPFVILYLIVRYHRSQKVDRSNPVDSNLKLELTWTIIPLILVMLV
FFWGAFLYVQMRTPPARTLDVYVIGKQWMWHVQHPNGKRENNELHVPIGQPVKLIMTSQDVIHSFYIPAFRVKQDVLPGR
YTIMWFEATKPGEYHLFCAEYCGTEHSLMIGRVVAMPLADYERWLATPGPVVLPDGSIDTGQPTITANLGDPMAAAGSQL
FTSLGCAGCHAMAGGGVGPSMQGLYGATEKMADGSTVTADENYLRESILNPNAKIVAGYPAVMPSYQGQISEDQLNQLIA
YIKSLADTGN

Sequences:

>Translated_330_residues
MRDFPLFPDQASTFATQVDQLYFFLVALSLIFAGVLPFVILYLIVRYHRSQKVDRSNPVDSNLKLELTWTIIPLILVMLV
FFWGAFLYVQMRTPPARTLDVYVIGKQWMWHVQHPNGKRENNELHVPIGQPVKLIMTSQDVIHSFYIPAFRVKQDVLPGR
YTIMWFEATKPGEYHLFCAEYCGTEHSLMIGRVVAMPLADYERWLATPGPVVLPDGSIDTGQPTITANLGDPMAAAGSQL
FTSLGCAGCHAMAGGGVGPSMQGLYGATEKMADGSTVTADENYLRESILNPNAKIVAGYPAVMPSYQGQISEDQLNQLIA
YIKSLADTGN
>Mature_330_residues
MRDFPLFPDQASTFATQVDQLYFFLVALSLIFAGVLPFVILYLIVRYHRSQKVDRSNPVDSNLKLELTWTIIPLILVMLV
FFWGAFLYVQMRTPPARTLDVYVIGKQWMWHVQHPNGKRENNELHVPIGQPVKLIMTSQDVIHSFYIPAFRVKQDVLPGR
YTIMWFEATKPGEYHLFCAEYCGTEHSLMIGRVVAMPLADYERWLATPGPVVLPDGSIDTGQPTITANLGDPMAAAGSQL
FTSLGCAGCHAMAGGGVGPSMQGLYGATEKMADGSTVTADENYLRESILNPNAKIVAGYPAVMPSYQGQISEDQLNQLIA
YIKSLADTGN

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=161, Percent_Identity=29.8136645962733, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1786635, Length=199, Percent_Identity=27.1356783919598, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6226540, Length=225, Percent_Identity=23.1111111111111, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 36599; Mature: 36599

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFPLFPDQASTFATQVDQLYFFLVALSLIFAGVLPFVILYLIVRYHRSQKVDRSNPVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SNLKLELTWTIIPLILVMLVFFWGAFLYVQMRTPPARTLDVYVIGKQWMWHVQHPNGKRE
CCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCEEEEEEECCCCCCC
NNELHVPIGQPVKLIMTSQDVIHSFYIPAFRVKQDVLPGRYTIMWFEATKPGEYHLFCAE
CCEEEEECCCCEEEEEECHHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCCCCEEEEEHH
YCGTEHSLMIGRVVAMPLADYERWLATPGPVVLPDGSIDTGQPTITANLGDPMAAAGSQL
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHH
FTSLGCAGCHAMAGGGVGPSMQGLYGATEKMADGSTVTADENYLRESILNPNAKIVAGYP
HHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHCCCCEEECCHHHHHHHHCCCCCEEEECCC
AVMPSYQGQISEDQLNQLIAYIKSLADTGN
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRDFPLFPDQASTFATQVDQLYFFLVALSLIFAGVLPFVILYLIVRYHRSQKVDRSNPVD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SNLKLELTWTIIPLILVMLVFFWGAFLYVQMRTPPARTLDVYVIGKQWMWHVQHPNGKRE
CCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCEEEEEEECCCCCCC
NNELHVPIGQPVKLIMTSQDVIHSFYIPAFRVKQDVLPGRYTIMWFEATKPGEYHLFCAE
CCEEEEECCCCEEEEEECHHHHHHHCCCHHHHHHHCCCCEEEEEEEECCCCCCEEEEEHH
YCGTEHSLMIGRVVAMPLADYERWLATPGPVVLPDGSIDTGQPTITANLGDPMAAAGSQL
HCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHH
FTSLGCAGCHAMAGGGVGPSMQGLYGATEKMADGSTVTADENYLRESILNPNAKIVAGYP
HHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHCCCCEEECCHHHHHHHHCCCCCEEEECCC
AVMPSYQGQISEDQLNQLIAYIKSLADTGN
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]