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The map label for this gene is nuoC2 [H]

Identifier: 222525395

GI number: 222525395

Start: 2719181

End: 2719702

Strand: Reverse

Name: nuoC2 [H]

Synonym: Chy400_2140

Alternate gene names: 222525395

Gene position: 2719702-2719181 (Counterclockwise)

Preceding gene: 222525396

Following gene: 222525394

Centisome position: 51.62

GC content: 56.51

Gene sequence:

>522_bases
ATGCCTGAACTGACACCAACCGATCTGCGGACACGACTGGCCACGGCGCTGCCGGATGCCCTGATCGAGGTGGAACCCCT
GGCGATCACGCCACCACCTGCTCACGGCCCCCAACCCGGTCTGTTTCATCCACCCGATCCGTTTATTCACCCCGATCATC
TCGTTGCGGCAGCCCTTTTTGTGCGCGATACGCTCGGTTATGCCTTTCTGTCCGATATTGCCGTGGTCGATTACCTTCAC
GCCGGCTGTTTTGAATTAGTCTATCGGTTCTACCATCCGGCAGGCGGTCCGGGTATTGTGTTACGGGTACGGGTACCACG
GGATGCGCCTTCCGTGCCATCACTCACGCCACACTGGCCGGCAGCTAACTTTCATGAGCGTGAGGCGTTCGATCTGTTTG
GCATCGAATTTGTCGGCCATCCATACCTGCGGCGCATCTATATGTGGGACGAGTTTGAAGGTTTTCCCATGCGCAAAGAT
TTTCCTCGACAGGGAGACAAATATCTGGGTAGCGACGAATAG

Upstream 100 bases:

>100_bases
CCAATCATGGATCCCGAAGTAGAGCTTGAGAATGCGCTCAAGGCGCGTGGGATCGCTCCTGAGATCGCAGCCGACGACTT
GAAACGGAGTGTGGTGAACG

Downstream 100 bases:

>100_bases
TCAGGCTTGATTGTCAATACTATTGTTCATATCTTCGCTTGCAAGAAGCGATACCCATAGAGAACTGGTGTCGATATGCT
CCAAACGCAAGAGCTGCAAG

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C 2; NDH-1 subunit C 2 [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MPELTPTDLRTRLATALPDALIEVEPLAITPPPAHGPQPGLFHPPDPFIHPDHLVAAALFVRDTLGYAFLSDIAVVDYLH
AGCFELVYRFYHPAGGPGIVLRVRVPRDAPSVPSLTPHWPAANFHEREAFDLFGIEFVGHPYLRRIYMWDEFEGFPMRKD
FPRQGDKYLGSDE

Sequences:

>Translated_173_residues
MPELTPTDLRTRLATALPDALIEVEPLAITPPPAHGPQPGLFHPPDPFIHPDHLVAAALFVRDTLGYAFLSDIAVVDYLH
AGCFELVYRFYHPAGGPGIVLRVRVPRDAPSVPSLTPHWPAANFHEREAFDLFGIEFVGHPYLRRIYMWDEFEGFPMRKD
FPRQGDKYLGSDE
>Mature_172_residues
PELTPTDLRTRLATALPDALIEVEPLAITPPPAHGPQPGLFHPPDPFIHPDHLVAAALFVRDTLGYAFLSDIAVVDYLHA
GCFELVYRFYHPAGGPGIVLRVRVPRDAPSVPSLTPHWPAANFHEREAFDLFGIEFVGHPYLRRIYMWDEFEGFPMRKDF
PRQGDKYLGSDE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=140, Percent_Identity=35, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI145693162, Length=88, Percent_Identity=39.7727272727273, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 19496; Mature: 19365

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELTPTDLRTRLATALPDALIEVEPLAITPPPAHGPQPGLFHPPDPFIHPDHLVAAALF
CCCCCHHHHHHHHHHHCCHHHEECCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VRDTLGYAFLSDIAVVDYLHAGCFELVYRFYHPAGGPGIVLRVRVPRDAPSVPSLTPHWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC
AANFHEREAFDLFGIEFVGHPYLRRIYMWDEFEGFPMRKDFPRQGDKYLGSDE
CCCCCCCCHHHHHCHHHHCCHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PELTPTDLRTRLATALPDALIEVEPLAITPPPAHGPQPGLFHPPDPFIHPDHLVAAALF
CCCCHHHHHHHHHHHCCHHHEECCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VRDTLGYAFLSDIAVVDYLHAGCFELVYRFYHPAGGPGIVLRVRVPRDAPSVPSLTPHWP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC
AANFHEREAFDLFGIEFVGHPYLRRIYMWDEFEGFPMRKDFPRQGDKYLGSDE
CCCCCCCCHHHHHCHHHHCCHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA