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The map label for this gene is nuoI2 [H]

Identifier: 222525393

GI number: 222525393

Start: 2716923

End: 2717999

Strand: Reverse

Name: nuoI2 [H]

Synonym: Chy400_2138

Alternate gene names: 222525393

Gene position: 2717999-2716923 (Counterclockwise)

Preceding gene: 222525394

Following gene: 222525392

Centisome position: 51.59

GC content: 61.1

Gene sequence:

>1077_bases
ATGACAGCACCACCATTCGAGATAGAGATTCCACGTGGGCGTGTGATTGAGGTGCAGCGCGATGACACCCGTGTCCGACG
GGGCAGTGGTTTGCTGCGGGGGATGGCTGTGATCTGGAAGCACTGGAAGGAGTCGTTCCGCCTGAACCGAAGCTATCGGC
AGATTCACGGTACCTTTACCATCCAGTATCCCGAAGAGCGACCGCGCATCCCCGAAACCTACCGCAACATGCCCATCCTC
CTCTACGACGACGAAACCGGTCACGAACTCTGTACCTCGTGCTTTCAGTGCGAACGCATTTGCCCGCCACAAGTAATTCA
TATGACGCAGGCGAAAGACCCGGCTACCGGTAAGCCAGTACCGGCTGTGGCCGAGTTTATCATCGAGTACGATGCCTGCA
TGAGCTGTGGTTTCTGCGCCGAAGTCTGTCCGTTCGATGCGATCAAGATGGATCACGAGTTCGAGTTATCGACCGACGAC
CACAGCAGTCTGACCGTGCATAAAGCGCAACTGAACCGACCCATCAGTTACTACGAGAAGATCGCTCCCACAATGTGGGC
TGAAGTTCGCGAGAGTGCATTGAAGAAGTTGCAGGGCAATATTCGCCGGCGGCCAGACGTGATCGGGATTGCCCCCCATC
TGACCGAACGGATTGCTGCCCGGCGAGCGGAACTGGCTGCGCAGGCACCTGCTTCACCACCTGAAGCTGCTACACCGGCA
GCTCCCGCCGAGGCTCGCAAACTGTCCCCTGAAGAGAAGGCGGCGAAACTGGCGGCCATCCGGGCGGCAAAGGCTGCCCA
GACCGGTGATGGCACGTCCCCTGCTGAAGGTGCATCACCGACAGCGCCTGCTCCCGCCGACGACAAAGCGGCGAAACTGG
CGGCCATCCGGGCGGCCAACGCGGCGAAGAAGGCCGCCGAAGGCGCCGCTCCCGCTCCAACCGGCGATGCGCCGGCGGCT
CCGACTACCCCTGCCGACGAGAAAGCGGCGCGGTTAGCAGCCATCCGGGCCGCCAACGCAGCGAAGCGAAAACAGGCCGA
GGAACAGGCACGTGACGGTTCGGGAGAGGAAGCATAA

Upstream 100 bases:

>100_bases
TCAACCTGACGCCCCTGGCCGATATGTGTCGTGGGTACAAGGTGGCCGATATTGTGGTCATTCTCGGCAGCATCGACATC
GTGATGGGAGAGGTGGATCG

Downstream 100 bases:

>100_bases
CCCGACGGAGAACCTTCATGTACGACATCTTGCAGGGACTCATTAACGGTACCTTTGGCTGGGGATGGCCCGATTGGTTG
ATCAACCTGATCGGCTACAT

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I 2; NDH-1 subunit I 2 [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTAPPFEIEIPRGRVIEVQRDDTRVRRGSGLLRGMAVIWKHWKESFRLNRSYRQIHGTFTIQYPEERPRIPETYRNMPIL
LYDDETGHELCTSCFQCERICPPQVIHMTQAKDPATGKPVPAVAEFIIEYDACMSCGFCAEVCPFDAIKMDHEFELSTDD
HSSLTVHKAQLNRPISYYEKIAPTMWAEVRESALKKLQGNIRRRPDVIGIAPHLTERIAARRAELAAQAPASPPEAATPA
APAEARKLSPEEKAAKLAAIRAAKAAQTGDGTSPAEGASPTAPAPADDKAAKLAAIRAANAAKKAAEGAAPAPTGDAPAA
PTTPADEKAARLAAIRAANAAKRKQAEEQARDGSGEEA

Sequences:

>Translated_358_residues
MTAPPFEIEIPRGRVIEVQRDDTRVRRGSGLLRGMAVIWKHWKESFRLNRSYRQIHGTFTIQYPEERPRIPETYRNMPIL
LYDDETGHELCTSCFQCERICPPQVIHMTQAKDPATGKPVPAVAEFIIEYDACMSCGFCAEVCPFDAIKMDHEFELSTDD
HSSLTVHKAQLNRPISYYEKIAPTMWAEVRESALKKLQGNIRRRPDVIGIAPHLTERIAARRAELAAQAPASPPEAATPA
APAEARKLSPEEKAAKLAAIRAAKAAQTGDGTSPAEGASPTAPAPADDKAAKLAAIRAANAAKKAAEGAAPAPTGDAPAA
PTTPADEKAARLAAIRAANAAKRKQAEEQARDGSGEEA
>Mature_357_residues
TAPPFEIEIPRGRVIEVQRDDTRVRRGSGLLRGMAVIWKHWKESFRLNRSYRQIHGTFTIQYPEERPRIPETYRNMPILL
YDDETGHELCTSCFQCERICPPQVIHMTQAKDPATGKPVPAVAEFIIEYDACMSCGFCAEVCPFDAIKMDHEFELSTDDH
SSLTVHKAQLNRPISYYEKIAPTMWAEVRESALKKLQGNIRRRPDVIGIAPHLTERIAARRAELAAQAPASPPEAATPAA
PAEARKLSPEEKAAKLAAIRAAKAAQTGDGTSPAEGASPTAPAPADDKAAKLAAIRAANAAKKAAEGAAPAPTGDAPAAP
TTPADEKAARLAAIRAANAAKRKQAEEQARDGSGEEA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Drosophila melanogaster, GI17864306, Length=182, Percent_Identity=32.4175824175824, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38754; Mature: 38623

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPPFEIEIPRGRVIEVQRDDTRVRRGSGLLRGMAVIWKHWKESFRLNRSYRQIHGTFT
CCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECEEE
IQYPEERPRIPETYRNMPILLYDDETGHELCTSCFQCERICPPQVIHMTQAKDPATGKPV
EECCCCCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHEEHHCCCCCCCCCCH
PAVAEFIIEYDACMSCGFCAEVCPFDAIKMDHEFELSTDDHSSLTVHKAQLNRPISYYEK
HHHHHHHHHHHHHHCCCCHHHHCCCHHEECCCCEECCCCCCCCEEEEHHHHCCCHHHHHH
IAPTMWAEVRESALKKLQGNIRRRPDVIGIAPHLTERIAARRAELAAQAPASPPEAATPA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
APAEARKLSPEEKAAKLAAIRAAKAAQTGDGTSPAEGASPTAPAPADDKAAKLAAIRAAN
CCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AAKKAAEGAAPAPTGDAPAAPTTPADEKAARLAAIRAANAAKRKQAEEQARDGSGEEA
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAPPFEIEIPRGRVIEVQRDDTRVRRGSGLLRGMAVIWKHWKESFRLNRSYRQIHGTFT
CCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECEEE
IQYPEERPRIPETYRNMPILLYDDETGHELCTSCFQCERICPPQVIHMTQAKDPATGKPV
EECCCCCCCCCHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHEEHHCCCCCCCCCCH
PAVAEFIIEYDACMSCGFCAEVCPFDAIKMDHEFELSTDDHSSLTVHKAQLNRPISYYEK
HHHHHHHHHHHHHHCCCCHHHHCCCHHEECCCCEECCCCCCCCEEEEHHHHCCCHHHHHH
IAPTMWAEVRESALKKLQGNIRRRPDVIGIAPHLTERIAARRAELAAQAPASPPEAATPA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
APAEARKLSPEEKAAKLAAIRAAKAAQTGDGTSPAEGASPTAPAPADDKAAKLAAIRAAN
CCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AAKKAAEGAAPAPTGDAPAAPTTPADEKAARLAAIRAANAAKRKQAEEQARDGSGEEA
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA