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The map label for this gene is rsbRA [H]

Identifier: 222525357

GI number: 222525357

Start: 2672668

End: 2673675

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_2102

Alternate gene names: 222525357

Gene position: 2672668-2673675 (Clockwise)

Preceding gene: 222525356

Following gene: 222525358

Centisome position: 50.72

GC content: 55.36

Gene sequence:

>1008_bases
GTGAAAATTGATCAACGGCAACTGGCATTTGTGCTGATGGGCGGAATGGCCGGCTATACACTGATTCGTGGTCTTGTCAA
TCTCATCGTCGGCGATCCGCTGCTGACGATTATCCTGACCCTCATCGTCTCGGCGATTTTTAGTGTAGCAACCTGGCTCT
ACTGGCGCGGTTGGGAAGGCGCACGTGCCTTTGCCACCACCGGTGTGGCGCTGGTGGTGGCGTTTGGGTTACCGCTTGAT
GAACAAACGATAGTGCTCTTCACTCCCCTGGCCTTTGCTGTCGCGATTACCAATACGCAGTGGGTAGCCGGTATCGGTCT
GGCAATGATTGGCATCTTGTTGGGGCGTGATGTCTTGAATGATGGCCTATTCAATAGTGTCTATGCCGATATTGGTGTAC
TGGCAAGCTATCTGGTACAGGTTGCTGCGTTTGCCGCTGCCCGATTTGCGCTTGACGGAGCACGGGTTGAGGCTGAACAA
AATGCGGCCCGGGCCGAGGCTGCCAGACGTGAGATAGAAGAACGCGCACGCGCAATTGAACAGCAGCGTGTGGAATTGCA
AGAGCAAAACCAACGTCAGCAAGAGCTGCTCGAACTGGTGAGCCAGCTTGAAACGCCGGCGGTGCGAATCGCCGATGGTG
TGCTGCTGGCGCCTCTGGTTGGTGGTATCGATAGTCGTCGGGCCGGTAAGATTACCAGCCGTCTGCTGGAACTGGTCTAT
GAACGACGGGTTAACCTGGTGATTATCGATGTCGCTGGCGTGCCGGTCATCGATACAGCGGTTGCCAATGCGTTGACGCA
GACGGTGCGCGCCCTGCGATTGCTTGGTTGTCGAGTCACCCTCACCGGTATTTCATCACAGGTGGCGCTTACCCTCACCC
ATATCGGGATTGAGCTGAGTGAACTTGAGGTGGCTGCTTCACCACAAGAGGCATTGCAACGCTGGATGGAGACGCAGACA
TCGGTTATTCGTAACCGACGCAACGGTGGCGATGAATTGTTGAATTGA

Upstream 100 bases:

>100_bases
GAGGCAAGAGCAGCGGCCAATGTTGGTGACGCTTCCATACGGTGGGTCTGACCTCTGCCTGTGTGTCCAAATACATCCTG
GAGTATGATGGGGAGGCTGT

Downstream 100 bases:

>100_bases
TGCAGGTGAACAGCGATAGCCCATTATGCTCTCGCTGCCTCACCATGGTTAAACAACGTCTGGCAGATGCTAACGTATGT
AGAGCAATAAAGGCATGTCG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKIDQRQLAFVLMGGMAGYTLIRGLVNLIVGDPLLTIILTLIVSAIFSVATWLYWRGWEGARAFATTGVALVVAFGLPLD
EQTIVLFTPLAFAVAITNTQWVAGIGLAMIGILLGRDVLNDGLFNSVYADIGVLASYLVQVAAFAAARFALDGARVEAEQ
NAARAEAARREIEERARAIEQQRVELQEQNQRQQELLELVSQLETPAVRIADGVLLAPLVGGIDSRRAGKITSRLLELVY
ERRVNLVIIDVAGVPVIDTAVANALTQTVRALRLLGCRVTLTGISSQVALTLTHIGIELSELEVAASPQEALQRWMETQT
SVIRNRRNGGDELLN

Sequences:

>Translated_335_residues
MKIDQRQLAFVLMGGMAGYTLIRGLVNLIVGDPLLTIILTLIVSAIFSVATWLYWRGWEGARAFATTGVALVVAFGLPLD
EQTIVLFTPLAFAVAITNTQWVAGIGLAMIGILLGRDVLNDGLFNSVYADIGVLASYLVQVAAFAAARFALDGARVEAEQ
NAARAEAARREIEERARAIEQQRVELQEQNQRQQELLELVSQLETPAVRIADGVLLAPLVGGIDSRRAGKITSRLLELVY
ERRVNLVIIDVAGVPVIDTAVANALTQTVRALRLLGCRVTLTGISSQVALTLTHIGIELSELEVAASPQEALQRWMETQT
SVIRNRRNGGDELLN
>Mature_335_residues
MKIDQRQLAFVLMGGMAGYTLIRGLVNLIVGDPLLTIILTLIVSAIFSVATWLYWRGWEGARAFATTGVALVVAFGLPLD
EQTIVLFTPLAFAVAITNTQWVAGIGLAMIGILLGRDVLNDGLFNSVYADIGVLASYLVQVAAFAAARFALDGARVEAEQ
NAARAEAARREIEERARAIEQQRVELQEQNQRQQELLELVSQLETPAVRIADGVLLAPLVGGIDSRRAGKITSRLLELVY
ERRVNLVIIDVAGVPVIDTAVANALTQTVRALRLLGCRVTLTGISSQVALTLTHIGIELSELEVAASPQEALQRWMETQT
SVIRNRRNGGDELLN

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 36348; Mature: 36348

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDQRQLAFVLMGGMAGYTLIRGLVNLIVGDPLLTIILTLIVSAIFSVATWLYWRGWEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ARAFATTGVALVVAFGLPLDEQTIVLFTPLAFAVAITNTQWVAGIGLAMIGILLGRDVLN
CHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DGLFNSVYADIGVLASYLVQVAAFAAARFALDGARVEAEQNAARAEAARREIEERARAIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRVELQEQNQRQQELLELVSQLETPAVRIADGVLLAPLVGGIDSRRAGKITSRLLELVY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
ERRVNLVIIDVAGVPVIDTAVANALTQTVRALRLLGCRVTLTGISSQVALTLTHIGIELS
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCHH
ELEVAASPQEALQRWMETQTSVIRNRRNGGDELLN
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MKIDQRQLAFVLMGGMAGYTLIRGLVNLIVGDPLLTIILTLIVSAIFSVATWLYWRGWEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ARAFATTGVALVVAFGLPLDEQTIVLFTPLAFAVAITNTQWVAGIGLAMIGILLGRDVLN
CHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DGLFNSVYADIGVLASYLVQVAAFAAARFALDGARVEAEQNAARAEAARREIEERARAIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRVELQEQNQRQQELLELVSQLETPAVRIADGVLLAPLVGGIDSRRAGKITSRLLELVY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
ERRVNLVIIDVAGVPVIDTAVANALTQTVRALRLLGCRVTLTGISSQVALTLTHIGIELS
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCHH
ELEVAASPQEALQRWMETQTSVIRNRRNGGDELLN
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]