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The map label for this gene is 222525269

Identifier: 222525269

GI number: 222525269

Start: 2545097

End: 2545993

Strand: Direct

Name: 222525269

Synonym: Chy400_2009

Alternate gene names: NA

Gene position: 2545097-2545993 (Clockwise)

Preceding gene: 222525268

Following gene: 222525270

Centisome position: 48.3

GC content: 59.75

Gene sequence:

>897_bases
ATGCGCGCCTTTTATTCTGATACGTTTGTCTTGCCACTACCGCCAGGGCACCGTTTTCCGATGGAGAAGTATGCGCTGCT
TCGGGAGCGGGTGCTGAGTGAGGGGATTGTAACGCCTGAGCGGTTGCACGTTCCCGAACCGGCCAGTATCACCGAGCTGT
GCCGGGCGCATGACGCGAACTACGTTGAGCGGGTCATCAATGGACACTTGACCAGTGCCGAAATTCGGCGCATCGGTTTT
CCCTGGTCGCCGCAGATGGTCGAACGCTCGCGGCGTTCGGCAGGGGCAACGATAGCCGCCTGTCGGGTAGCCCTGAGCGA
AGGGGTAGGCGTGAATCTGGCCGGTGGTACCCATCATGCCTTCGCCGATGCCGGCGCCGGCTATTGTGTGTTCAACGATG
CCGCCGTCGCCGCACGCGCCATGCAGTCCGAAGGACGTGTTCAACGCATTGCCATCATCGATTGCGATGTGCATCAGGGT
GATGGCACTGCGGCCATCTTCACGGGTGATCCAACCGTCTTTACCTTTTCGATTCACGGCGCTCACAATTTTCCTTTTCG
CAAACAGCAGAGTGACCTGGATATTGCCCTTCCTGATGCTACTGGCGATACGGCCTATCTCGATGCGCTGGAGTGGGGGG
TGCGCCAGGTCTTTGCAATTGCCCGCCCTGATCTGGTGATCTATCTGGCCGGTGCCGATCCCTATTACGACGACCGGCTG
GGTCGGTTGAGCCTGACCAAAGCCGGTCTGGCCGAGCGCGACCGTCTGGTCTTTAGCTACTGCCGGGCAGCAGGCGTACC
GGTTGCGGTGACGATGGCCGGCGGCTATGCCCGTCAGATCAGTGACACTGTTGACATTCACACCCATACCATTGCCACTG
CTGCCGGTTTACGGTGA

Upstream 100 bases:

>100_bases
ATTGATTCCTCTCACTGTCGCTCTGTTGGTTGTTCGAGCCTTGCGCTGGCTGGGGGAAGAGCGTCGCCAGCGTCAGCTTT
CAATGAATGCTTCGGAGTAG

Downstream 100 bases:

>100_bases
TCTTTCCAAATTCCTGGCATAGATGTTCCGATCCTGACATCCAAAATGGCAAAACCTTCGCACAGATAGATGAAGGCGCA
TGCACGGGCATGCACCAAAC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRAFYSDTFVLPLPPGHRFPMEKYALLRERVLSEGIVTPERLHVPEPASITELCRAHDANYVERVINGHLTSAEIRRIGF
PWSPQMVERSRRSAGATIAACRVALSEGVGVNLAGGTHHAFADAGAGYCVFNDAAVAARAMQSEGRVQRIAIIDCDVHQG
DGTAAIFTGDPTVFTFSIHGAHNFPFRKQQSDLDIALPDATGDTAYLDALEWGVRQVFAIARPDLVIYLAGADPYYDDRL
GRLSLTKAGLAERDRLVFSYCRAAGVPVAVTMAGGYARQISDTVDIHTHTIATAAGLR

Sequences:

>Translated_298_residues
MRAFYSDTFVLPLPPGHRFPMEKYALLRERVLSEGIVTPERLHVPEPASITELCRAHDANYVERVINGHLTSAEIRRIGF
PWSPQMVERSRRSAGATIAACRVALSEGVGVNLAGGTHHAFADAGAGYCVFNDAAVAARAMQSEGRVQRIAIIDCDVHQG
DGTAAIFTGDPTVFTFSIHGAHNFPFRKQQSDLDIALPDATGDTAYLDALEWGVRQVFAIARPDLVIYLAGADPYYDDRL
GRLSLTKAGLAERDRLVFSYCRAAGVPVAVTMAGGYARQISDTVDIHTHTIATAAGLR
>Mature_298_residues
MRAFYSDTFVLPLPPGHRFPMEKYALLRERVLSEGIVTPERLHVPEPASITELCRAHDANYVERVINGHLTSAEIRRIGF
PWSPQMVERSRRSAGATIAACRVALSEGVGVNLAGGTHHAFADAGAGYCVFNDAAVAARAMQSEGRVQRIAIIDCDVHQG
DGTAAIFTGDPTVFTFSIHGAHNFPFRKQQSDLDIALPDATGDTAYLDALEWGVRQVFAIARPDLVIYLAGADPYYDDRL
GRLSLTKAGLAERDRLVFSYCRAAGVPVAVTMAGGYARQISDTVDIHTHTIATAAGLR

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=301, Percent_Identity=31.5614617940199, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI209862883, Length=268, Percent_Identity=32.089552238806, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI13128862, Length=285, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI13128864, Length=296, Percent_Identity=26.3513513513513, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI13128860, Length=285, Percent_Identity=24.9122807017544, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI8923769, Length=299, Percent_Identity=23.7458193979933, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI293336691, Length=260, Percent_Identity=25.7692307692308, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI20070354, Length=292, Percent_Identity=27.7397260273973, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI169234807, Length=133, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI148539870, Length=133, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI17158039, Length=165, Percent_Identity=29.6969696969697, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI30795204, Length=165, Percent_Identity=29.6969696969697, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI30795202, Length=165, Percent_Identity=29.6969696969697, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=279, Percent_Identity=28.3154121863799, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17508561, Length=289, Percent_Identity=26.2975778546713, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540334, Length=175, Percent_Identity=32, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540332, Length=175, Percent_Identity=32, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=284, Percent_Identity=26.056338028169, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193206283, Length=175, Percent_Identity=32, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17537347, Length=290, Percent_Identity=27.9310344827586, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193209491, Length=177, Percent_Identity=31.0734463276836, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534739, Length=178, Percent_Identity=27.5280898876405, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323999, Length=291, Percent_Identity=25.4295532646048, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6321244, Length=294, Percent_Identity=25.5102040816327, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324307, Length=208, Percent_Identity=28.8461538461538, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325325, Length=177, Percent_Identity=25.9887005649718, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649807, Length=257, Percent_Identity=34.2412451361868, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24657891, Length=305, Percent_Identity=25.5737704918033, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644244, Length=290, Percent_Identity=22.0689655172414, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281360899, Length=284, Percent_Identity=28.5211267605634, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24642144, Length=284, Percent_Identity=28.5211267605634, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24642142, Length=284, Percent_Identity=28.5211267605634, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24642146, Length=284, Percent_Identity=28.5211267605634, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32309; Mature: 32309

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFYSDTFVLPLPPGHRFPMEKYALLRERVLSEGIVTPERLHVPEPASITELCRAHDAN
CCCEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHCCCH
YVERVINGHLTSAEIRRIGFPWSPQMVERSRRSAGATIAACRVALSEGVGVNLAGGTHHA
HHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCHH
FADAGAGYCVFNDAAVAARAMQSEGRVQRIAIIDCDVHQGDGTAAIFTGDPTVFTFSIHG
HHCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECCCEEEEEEECC
AHNFPFRKQQSDLDIALPDATGDTAYLDALEWGVRQVFAIARPDLVIYLAGADPYYDDRL
CCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GRLSLTKAGLAERDRLVFSYCRAAGVPVAVTMAGGYARQISDTVDIHTHTIATAAGLR
CEEEEHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCHHEEEHHHHHHHCCCC
>Mature Secondary Structure
MRAFYSDTFVLPLPPGHRFPMEKYALLRERVLSEGIVTPERLHVPEPASITELCRAHDAN
CCCEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHCCCH
YVERVINGHLTSAEIRRIGFPWSPQMVERSRRSAGATIAACRVALSEGVGVNLAGGTHHA
HHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCHH
FADAGAGYCVFNDAAVAARAMQSEGRVQRIAIIDCDVHQGDGTAAIFTGDPTVFTFSIHG
HHCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECCCEEEEEEECC
AHNFPFRKQQSDLDIALPDATGDTAYLDALEWGVRQVFAIARPDLVIYLAGADPYYDDRL
CCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GRLSLTKAGLAERDRLVFSYCRAAGVPVAVTMAGGYARQISDTVDIHTHTIATAAGLR
CEEEEHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCHHEEEHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]