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The map label for this gene is manA [H]

Identifier: 222525249

GI number: 222525249

Start: 2524014

End: 2525048

Strand: Reverse

Name: manA [H]

Synonym: Chy400_1989

Alternate gene names: 222525249

Gene position: 2525048-2524014 (Counterclockwise)

Preceding gene: 222525250

Following gene: 222525248

Centisome position: 47.92

GC content: 61.26

Gene sequence:

>1035_bases
ATGCAGACACTCTATCCAATTCTCTGTGAACCGCGCCTGGTTGAACCGCTCTGGGGTGGTCAACGACTGGCACCGTGGCT
CGATCTGCCGCACCCCCATCCAGAACGGCTGGGTGAAATCTGGCTGGTCTTCGATAGCAATCGGGTCAGCAACGGCCCCC
TGGCCGGCACAACGATTGCCGATCTGGCCCGTGCCTACGGCACCGCCCTGGTCGGTTCCCGACCGTTCGCCCGCTACGGT
GCCGATCTACCGTTGCTGGCGAAATTCATTGATGCCGCCGACCGCCTCTCGGTACAGGTGCATCCCGACGATGAGTATGC
CCATACGTTTGAGGCGCATACCGGCTTCCACGGCAAAACCGAAGCCTGGTACATTCTGGCTGCCGAACCGGGGGCAACGG
TGACATTGGGCACGTCCACGGTGCTGGAACGTGAGACACTGGCGCGGGCAATCGCTGATGGTACCGTCGAAACCCTCCTG
GCGCAGCGGCCGGTTCAGTCCGGCGACCTGATCTTCGTACCGGCGGGGACGATTCACGCCATCAACGCCGGGATTATGCT
GTTTGAAATTCAGCAGAAATCGGATCTTACCTATCGCCTGTACGATTACAACCGCCGCGATGCCCGTACCGGTCAGCTCC
GCCCGCTGCACATCGAGCAGGCGCTGGCGGTGAGTCGGCTGGAACCGGCGCACACTGCCCGGTTGCGTCCACTGCCGCTC
GATGCACAACGCGAATTGCTGGTAGCCTGCTCATCATTTGCACTCGAACGCTGGCGCGTGCAGGGAGAAGTAGCGGCGAA
GACCGACCCCGCTTCGCTTGAGATCCTCACCGTCATTGGCGGGACGGCACAGCTTACCTGGCAACAGCTTACCCTCGACC
TGCCACGCGGAACGGCGGTCCTCTTGCCGGCAACCCTGGGAGCGTACCGACTTCTCGCCGATGATGCAACCCTGTTGCGT
TCATATATTCCCGATATACCGGCGTTAATCAGCACACTTGGCGTATCACCGGGTACCGGTCCAATCTTCCCCTAA

Upstream 100 bases:

>100_bases
AGTCGGTCTGCAACAGATCGAACGCCATGTTGAGGGTGAGTGGGTGGCTCTGGTTCACCGTCGCCCACAATAGACCTGAT
TTCGATAAAGACGCAAACCT

Downstream 100 bases:

>100_bases
AGCCGATGGTTGATGACACACTCGCAATTCCCAACACACGCCGCTTCTTCGTCAATCCTGGCTGGCTACGCACCGATCAG
GTAGAGATTGATGATGCGGC

Product: Mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MQTLYPILCEPRLVEPLWGGQRLAPWLDLPHPHPERLGEIWLVFDSNRVSNGPLAGTTIADLARAYGTALVGSRPFARYG
ADLPLLAKFIDAADRLSVQVHPDDEYAHTFEAHTGFHGKTEAWYILAAEPGATVTLGTSTVLERETLARAIADGTVETLL
AQRPVQSGDLIFVPAGTIHAINAGIMLFEIQQKSDLTYRLYDYNRRDARTGQLRPLHIEQALAVSRLEPAHTARLRPLPL
DAQRELLVACSSFALERWRVQGEVAAKTDPASLEILTVIGGTAQLTWQQLTLDLPRGTAVLLPATLGAYRLLADDATLLR
SYIPDIPALISTLGVSPGTGPIFP

Sequences:

>Translated_344_residues
MQTLYPILCEPRLVEPLWGGQRLAPWLDLPHPHPERLGEIWLVFDSNRVSNGPLAGTTIADLARAYGTALVGSRPFARYG
ADLPLLAKFIDAADRLSVQVHPDDEYAHTFEAHTGFHGKTEAWYILAAEPGATVTLGTSTVLERETLARAIADGTVETLL
AQRPVQSGDLIFVPAGTIHAINAGIMLFEIQQKSDLTYRLYDYNRRDARTGQLRPLHIEQALAVSRLEPAHTARLRPLPL
DAQRELLVACSSFALERWRVQGEVAAKTDPASLEILTVIGGTAQLTWQQLTLDLPRGTAVLLPATLGAYRLLADDATLLR
SYIPDIPALISTLGVSPGTGPIFP
>Mature_344_residues
MQTLYPILCEPRLVEPLWGGQRLAPWLDLPHPHPERLGEIWLVFDSNRVSNGPLAGTTIADLARAYGTALVGSRPFARYG
ADLPLLAKFIDAADRLSVQVHPDDEYAHTFEAHTGFHGKTEAWYILAAEPGATVTLGTSTVLERETLARAIADGTVETLL
AQRPVQSGDLIFVPAGTIHAINAGIMLFEIQQKSDLTYRLYDYNRRDARTGQLRPLHIEQALAVSRLEPAHTARLRPLPL
DAQRELLVACSSFALERWRVQGEVAAKTDPASLEILTVIGGTAQLTWQQLTLDLPRGTAVLLPATLGAYRLLADDATLLR
SYIPDIPALISTLGVSPGTGPIFP

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 37552; Mature: 37552

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLYPILCEPRLVEPLWGGQRLAPWLDLPHPHPERLGEIWLVFDSNRVSNGPLAGTTIA
CCCCCCHHCCCCEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCCCCCHHH
DLARAYGTALVGSRPFARYGADLPLLAKFIDAADRLSVQVHPDDEYAHTFEAHTGFHGKT
HHHHHHHHHHCCCCCHHHHCCCHHHHHHHHCHHHHEEEEECCCCCHHHEEHHCCCCCCCC
EAWYILAAEPGATVTLGTSTVLERETLARAIADGTVETLLAQRPVQSGDLIFVPAGTIHA
CEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCEEE
INAGIMLFEIQQKSDLTYRLYDYNRRDARTGQLRPLHIEQALAVSRLEPAHTARLRPLPL
ECCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHCCCHHHCCCCCCCC
DAQRELLVACSSFALERWRVQGEVAAKTDPASLEILTVIGGTAQLTWQQLTLDLPRGTAV
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCEEEEEEEEEECCCCCEE
LLPATLGAYRLLADDATLLRSYIPDIPALISTLGVSPGTGPIFP
EEECCCCHHHHHHCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQTLYPILCEPRLVEPLWGGQRLAPWLDLPHPHPERLGEIWLVFDSNRVSNGPLAGTTIA
CCCCCCHHCCCCEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCCCCCHHH
DLARAYGTALVGSRPFARYGADLPLLAKFIDAADRLSVQVHPDDEYAHTFEAHTGFHGKT
HHHHHHHHHHCCCCCHHHHCCCHHHHHHHHCHHHHEEEEECCCCCHHHEEHHCCCCCCCC
EAWYILAAEPGATVTLGTSTVLERETLARAIADGTVETLLAQRPVQSGDLIFVPAGTIHA
CEEEEEEECCCCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCEEE
INAGIMLFEIQQKSDLTYRLYDYNRRDARTGQLRPLHIEQALAVSRLEPAHTARLRPLPL
ECCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHHCCCHHHCCCCCCCC
DAQRELLVACSSFALERWRVQGEVAAKTDPASLEILTVIGGTAQLTWQQLTLDLPRGTAV
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEECCCCEEEEEEEEEECCCCCEE
LLPATLGAYRLLADDATLLRSYIPDIPALISTLGVSPGTGPIFP
EEECCCCHHHHHHCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]