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The map label for this gene is prmA

Identifier: 222525250

GI number: 222525250

Start: 2525076

End: 2526062

Strand: Reverse

Name: prmA

Synonym: Chy400_1990

Alternate gene names: 222525250

Gene position: 2526062-2525076 (Counterclockwise)

Preceding gene: 222525251

Following gene: 222525249

Centisome position: 47.94

GC content: 60.69

Gene sequence:

>987_bases
ATGCAAACAACATCCTGGCTCGAAATTGCAGTTGAAGTTGACCCGGAAGCCGTGGAAACGGTGTCCGAAATCCTGGCCCG
TTACGGCTACAATGGTGGTGTCGTGGTCGAGCAGAGCTGGATCGCTGGCGATGAAGGGCCAGAATTCCAGTACGATCCCA
ACCGACCGGTCTGGTTGCGTACCTATCTGCCACTCGACGCGCAGGCCGAAGAGACCCGTCAGCAGATCGAACATGCCCTC
TGGCACGTCCACCAGATTCGCCCGCTCGGCCCGATCCAGACTCGCACACTGGCCGAAGAAGACTGGGCGAACGCCTGGAA
GCAGTTTTACCCGGTGCTGCGCGTTGGCGAGCGCACGGTGATTGTGCCGTCGTGGCTGGAATATCAGCCGCAGCCGAACG
ATGTTGTCCTGCTGCTCGATCCGGGGATGGCGTTTGGTACCGGCCTCCACCCAACCACCCGTCTCTGCCTGCACCTGCTC
GAACGGCTGGTGCAACCCGGACAACAGGTGCTCGATCTCGGCACCGGCTCTGGGATTCTGGCGATTGCTGCGGCAAAACT
CGGTGCGGGTCAGGTACTGGCACTCGATAACGATCCGATAGCGGTACGGGTCGCGCACGAAAATGTTGAGCGCAATCAGG
TGCAAGACCTGGTGACGGTAGCCGAAGGCAGCCTGGGCGCCGGGCAGGCGATGGGGCACTGGCTGTCTGGCGATTTTGGG
CCGGAAACACCCGATCCCACCCTGCACGACAACACGCCCCAGGCCACCTTCGATCTGATCGCGGCCAATCTGATCGCGAA
AGTCCTGGTGCTGCTGGCGCCTGATCTGGCGACAGCTCTCAAACCCGGTGGTCTACTGATTAGTAGTGGTATCATTGATG
TCAAAGAGGCAGAGGTCGTAGCGGCCTTCGCCGCAGTCGGTCTGCAACAGATCGAACGCCATGTTGAGGGTGAGTGGGTG
GCTCTGGTTCACCGTCGCCCACAATAG

Upstream 100 bases:

>100_bases
CCTGGCCGATATGGTGCGCAACCGGTTGAGCGATCTGGGTGTCACGCTTGAGGATGGCCCGCAGGGCACGCGATGGAAGT
GGGAGAGGTGACGTACATTC

Downstream 100 bases:

>100_bases
ACCTGATTTCGATAAAGACGCAAACCTATGCAGACACTCTATCCAATTCTCTGTGAACCGCGCCTGGTTGAACCGCTCTG
GGGTGGTCAACGACTGGCAC

Product: 50S ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MQTTSWLEIAVEVDPEAVETVSEILARYGYNGGVVVEQSWIAGDEGPEFQYDPNRPVWLRTYLPLDAQAEETRQQIEHAL
WHVHQIRPLGPIQTRTLAEEDWANAWKQFYPVLRVGERTVIVPSWLEYQPQPNDVVLLLDPGMAFGTGLHPTTRLCLHLL
ERLVQPGQQVLDLGTGSGILAIAAAKLGAGQVLALDNDPIAVRVAHENVERNQVQDLVTVAEGSLGAGQAMGHWLSGDFG
PETPDPTLHDNTPQATFDLIAANLIAKVLVLLAPDLATALKPGGLLISSGIIDVKEAEVVAAFAAVGLQQIERHVEGEWV
ALVHRRPQ

Sequences:

>Translated_328_residues
MQTTSWLEIAVEVDPEAVETVSEILARYGYNGGVVVEQSWIAGDEGPEFQYDPNRPVWLRTYLPLDAQAEETRQQIEHAL
WHVHQIRPLGPIQTRTLAEEDWANAWKQFYPVLRVGERTVIVPSWLEYQPQPNDVVLLLDPGMAFGTGLHPTTRLCLHLL
ERLVQPGQQVLDLGTGSGILAIAAAKLGAGQVLALDNDPIAVRVAHENVERNQVQDLVTVAEGSLGAGQAMGHWLSGDFG
PETPDPTLHDNTPQATFDLIAANLIAKVLVLLAPDLATALKPGGLLISSGIIDVKEAEVVAAFAAVGLQQIERHVEGEWV
ALVHRRPQ
>Mature_328_residues
MQTTSWLEIAVEVDPEAVETVSEILARYGYNGGVVVEQSWIAGDEGPEFQYDPNRPVWLRTYLPLDAQAEETRQQIEHAL
WHVHQIRPLGPIQTRTLAEEDWANAWKQFYPVLRVGERTVIVPSWLEYQPQPNDVVLLLDPGMAFGTGLHPTTRLCLHLL
ERLVQPGQQVLDLGTGSGILAIAAAKLGAGQVLALDNDPIAVRVAHENVERNQVQDLVTVAEGSLGAGQAMGHWLSGDFG
PETPDPTLHDNTPQATFDLIAANLIAKVLVLLAPDLATALKPGGLLISSGIIDVKEAEVVAAFAAVGLQQIERHVEGEWV
ALVHRRPQ

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=124, Percent_Identity=48.3870967741936, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_CHLAA (A9WD89)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001635445.1
- ProteinModelPortal:   A9WD89
- SMR:   A9WD89
- GeneID:   5826289
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1839
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   CLSK974529
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 35815; Mature: 35815

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTSWLEIAVEVDPEAVETVSEILARYGYNGGVVVEQSWIAGDEGPEFQYDPNRPVWLR
CCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCEEEEECEECCCCCCCCCCCCCCCEEEE
TYLPLDAQAEETRQQIEHALWHVHQIRPLGPIQTRTLAEEDWANAWKQFYPVLRVGERTV
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IVPSWLEYQPQPNDVVLLLDPGMAFGTGLHPTTRLCLHLLERLVQPGQQVLDLGTGSGIL
EEEHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCEE
AIAAAKLGAGQVLALDNDPIAVRVAHENVERNQVQDLVTVAEGSLGAGQAMGHWLSGDFG
EEEEHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
PETPDPTLHDNTPQATFDLIAANLIAKVLVLLAPDLATALKPGGLLISSGIIDVKEAEVV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCHHHHHH
AAFAAVGLQQIERHVEGEWVALVHRRPQ
HHHHHHHHHHHHHHHCCCEEEEEECCCC
>Mature Secondary Structure
MQTTSWLEIAVEVDPEAVETVSEILARYGYNGGVVVEQSWIAGDEGPEFQYDPNRPVWLR
CCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCEEEEECEECCCCCCCCCCCCCCCEEEE
TYLPLDAQAEETRQQIEHALWHVHQIRPLGPIQTRTLAEEDWANAWKQFYPVLRVGERTV
EECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
IVPSWLEYQPQPNDVVLLLDPGMAFGTGLHPTTRLCLHLLERLVQPGQQVLDLGTGSGIL
EEEHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCEE
AIAAAKLGAGQVLALDNDPIAVRVAHENVERNQVQDLVTVAEGSLGAGQAMGHWLSGDFG
EEEEHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
PETPDPTLHDNTPQATFDLIAANLIAKVLVLLAPDLATALKPGGLLISSGIIDVKEAEVV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCHHHHHH
AAFAAVGLQQIERHVEGEWVALVHRRPQ
HHHHHHHHHHHHHHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA