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The map label for this gene is hsdM [C]

Identifier: 222525218

GI number: 222525218

Start: 2486072

End: 2487658

Strand: Direct

Name: hsdM [C]

Synonym: Chy400_1958

Alternate gene names: 222525218

Gene position: 2486072-2487658 (Clockwise)

Preceding gene: 222525215

Following gene: 222525219

Centisome position: 47.18

GC content: 55.14

Gene sequence:

>1587_bases
TTGGCGAAACGAAAGAACCATGCCCAGGCTATCGAGACGACCGGCGCTAATTTAGGGTTCGAGCCCCAACTCTGGCAGAC
TGCCAATGCTCTCCGCGGCAGTATGGACGCGGCTGAGTATAAGCACGTTGTATTGGGTCTCATCTTTCTAAAATACATTT
CCGACGCCTTCGAGGAGCACCGTGAGAGGCTTCAGAATATCCCCAACGCCGATCCAGAAGATCCCGATGAATATCGGGCA
GATAATGTCTTCTGGGTTCCACCTGATGCCCGTTGGGTGGAACTCCGCAACAATGCTCGCCAGCCAAACATCGGCGAACT
GATTGATCAGGCGATGATAGCGGTGGAACGAGATAATCCCTCTCTCAAGGGGGTTCTCCCAAAAGACTATGCTCGCCCTG
CTCTGGACCAGCAGCGTTTGGGTCAGCTCATCGACCTTGTCTCGAACATCCCGGTGGGCACGGCCTCTGCCCGCTCCAAG
GACGTGCTTGGGCGCGTTTATGAATATTTCCTCTCGCAGTTTGCAAGTGCTGAGGGTAAGAAGGGTGGTGAGTTCTACAC
TCCCCGGTGCGTCGTGCGCCTGCTGGTGGAAATGTTGGAACCCTATCAAGGCCGGGTTTACGACCCTTGCTGCGGATCTG
CGGGGATGTTCATACAATCTGTAGAGTTTATCGAGGCCCATGCTACGGGAAACGGCAATGGTAGCCGCGCTCGTGCTCGC
ATCAGTATTTACGGACAAGAGCTTAACTATACTACCTGGCGTTTAGCAAAGATGAATCTGGCCATCCGTGGTATTGATGG
ACGGATCGAACAAGGCGATACCTTCCGCAATGACCGTTTCCCCGACCTCAAAGCCGATTACATTCTGGCAAATCCACCCT
TCAATATGAAAGAGTGGGGCGGTGAGCAGTTGCGCAACGACAAACGCTGGCAGTACGGTATACCGCCCGTTGGTAATGCC
AACTTCGCCTGGGTGCAGCATATTGTGCATCACCTTGCGCCTGCGGGAGTGGCCGGTTTTGTGCTTGCGAATGGCTCGAT
GTCCTCCAACCAATCTGGCGAGGGTGAGATTCGCAGGAAACTGATTGAAGCCGATCTTGTCGACTGTATGGTAGCACTGC
CGGGCCAACTCTTCTACTCGACTCAGATTCCGGCTTGCCTGTGGTTCCTCGCCCGCAATCGAAATAATGGCAAGTTCCGT
GACCGTCGTAAGCAGATTCTCTTTATCGACGCCCGCAGGCTGGGTCGCATGGTGGATCGCATCCATCGCGAGCTAACCGA
CGAAGAGATCGAACGAATCGCTTGTACCTATCACGCCTGGCGAGGGGAATCGGACGCTGGGGAATACCGGGACATCCCCG
GTTTCTGCAAGAGTGCGTCGCTGGAGGATGTGCGCAAACACGGCTATGTGCTGACTCCGGGCCGCTATGTTGGCTCCGAG
GTGCGGGAAGATGATGATGAGCCGTTCGCAGAGAAGATGCAGTGGCTTGTTGCCCAGCTCCGTGAGCAACAGGCTGAGGC
GGCGAAACTCGATGAGGCGATTGTTGCCAATCTGCAAGAACTGGGCTTTTGGGAGCAGAAGAGATGA

Upstream 100 bases:

>100_bases
GTGGTATGCGAAAGACGTAGGGGCGACGCATGCATCGCCCCCTACTGTCAGATGCCAGTATCATGGTCTCGGTGCGATTG
CGTCGATAAGGAGGCAAACA

Downstream 100 bases:

>100_bases
AGATACAGGTTGCTCCTGCGTTATTACGTTGGGCCTGTGAGCGAGCAGGTTTTCGTGAGGAAGATCTGAAAGGAAAATTT
CCCAGGCTCGACCGCTGGCT

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MAKRKNHAQAIETTGANLGFEPQLWQTANALRGSMDAAEYKHVVLGLIFLKYISDAFEEHRERLQNIPNADPEDPDEYRA
DNVFWVPPDARWVELRNNARQPNIGELIDQAMIAVERDNPSLKGVLPKDYARPALDQQRLGQLIDLVSNIPVGTASARSK
DVLGRVYEYFLSQFASAEGKKGGEFYTPRCVVRLLVEMLEPYQGRVYDPCCGSAGMFIQSVEFIEAHATGNGNGSRARAR
ISIYGQELNYTTWRLAKMNLAIRGIDGRIEQGDTFRNDRFPDLKADYILANPPFNMKEWGGEQLRNDKRWQYGIPPVGNA
NFAWVQHIVHHLAPAGVAGFVLANGSMSSNQSGEGEIRRKLIEADLVDCMVALPGQLFYSTQIPACLWFLARNRNNGKFR
DRRKQILFIDARRLGRMVDRIHRELTDEEIERIACTYHAWRGESDAGEYRDIPGFCKSASLEDVRKHGYVLTPGRYVGSE
VREDDDEPFAEKMQWLVAQLREQQAEAAKLDEAIVANLQELGFWEQKR

Sequences:

>Translated_528_residues
MAKRKNHAQAIETTGANLGFEPQLWQTANALRGSMDAAEYKHVVLGLIFLKYISDAFEEHRERLQNIPNADPEDPDEYRA
DNVFWVPPDARWVELRNNARQPNIGELIDQAMIAVERDNPSLKGVLPKDYARPALDQQRLGQLIDLVSNIPVGTASARSK
DVLGRVYEYFLSQFASAEGKKGGEFYTPRCVVRLLVEMLEPYQGRVYDPCCGSAGMFIQSVEFIEAHATGNGNGSRARAR
ISIYGQELNYTTWRLAKMNLAIRGIDGRIEQGDTFRNDRFPDLKADYILANPPFNMKEWGGEQLRNDKRWQYGIPPVGNA
NFAWVQHIVHHLAPAGVAGFVLANGSMSSNQSGEGEIRRKLIEADLVDCMVALPGQLFYSTQIPACLWFLARNRNNGKFR
DRRKQILFIDARRLGRMVDRIHRELTDEEIERIACTYHAWRGESDAGEYRDIPGFCKSASLEDVRKHGYVLTPGRYVGSE
VREDDDEPFAEKMQWLVAQLREQQAEAAKLDEAIVANLQELGFWEQKR
>Mature_527_residues
AKRKNHAQAIETTGANLGFEPQLWQTANALRGSMDAAEYKHVVLGLIFLKYISDAFEEHRERLQNIPNADPEDPDEYRAD
NVFWVPPDARWVELRNNARQPNIGELIDQAMIAVERDNPSLKGVLPKDYARPALDQQRLGQLIDLVSNIPVGTASARSKD
VLGRVYEYFLSQFASAEGKKGGEFYTPRCVVRLLVEMLEPYQGRVYDPCCGSAGMFIQSVEFIEAHATGNGNGSRARARI
SIYGQELNYTTWRLAKMNLAIRGIDGRIEQGDTFRNDRFPDLKADYILANPPFNMKEWGGEQLRNDKRWQYGIPPVGNAN
FAWVQHIVHHLAPAGVAGFVLANGSMSSNQSGEGEIRRKLIEADLVDCMVALPGQLFYSTQIPACLWFLARNRNNGKFRD
RRKQILFIDARRLGRMVDRIHRELTDEEIERIACTYHAWRGESDAGEYRDIPGFCKSASLEDVRKHGYVLTPGRYVGSEV
REDDDEPFAEKMQWLVAQLREQQAEAAKLDEAIVANLQELGFWEQKR

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=389, Percent_Identity=23.1362467866324, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 59980; Mature: 59849

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRKNHAQAIETTGANLGFEPQLWQTANALRGSMDAAEYKHVVLGLIFLKYISDAFEEH
CCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RERLQNIPNADPEDPDEYRADNVFWVPPDARWVELRNNARQPNIGELIDQAMIAVERDNP
HHHHHCCCCCCCCCCHHHCCCCEEECCCCCCEEHHHCCCCCCCHHHHHHHHHHEEECCCC
SLKGVLPKDYARPALDQQRLGQLIDLVSNIPVGTASARSKDVLGRVYEYFLSQFASAEGK
CCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KGGEFYTPRCVVRLLVEMLEPYQGRVYDPCCGSAGMFIQSVEFIEAHATGNGNGSRARAR
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEE
ISIYGQELNYTTWRLAKMNLAIRGIDGRIEQGDTFRNDRFPDLKADYILANPPFNMKEWG
EEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCC
GEQLRNDKRWQYGIPPVGNANFAWVQHIVHHLAPAGVAGFVLANGSMSSNQSGEGEIRRK
CHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCHHHHHHH
LIEADLVDCMVALPGQLFYSTQIPACLWFLARNRNNGKFRDRRKQILFIDARRLGRMVDR
HHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHCCCCCCHHHHCCEEEEEEHHHHHHHHHH
IHRELTDEEIERIACTYHAWRGESDAGEYRDIPGFCKSASLEDVRKHGYVLTPGRYVGSE
HHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHCCEEECCCHHHCCH
VREDDDEPFAEKMQWLVAQLREQQAEAAKLDEAIVANLQELGFWEQKR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKRKNHAQAIETTGANLGFEPQLWQTANALRGSMDAAEYKHVVLGLIFLKYISDAFEEH
CCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RERLQNIPNADPEDPDEYRADNVFWVPPDARWVELRNNARQPNIGELIDQAMIAVERDNP
HHHHHCCCCCCCCCCHHHCCCCEEECCCCCCEEHHHCCCCCCCHHHHHHHHHHEEECCCC
SLKGVLPKDYARPALDQQRLGQLIDLVSNIPVGTASARSKDVLGRVYEYFLSQFASAEGK
CCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KGGEFYTPRCVVRLLVEMLEPYQGRVYDPCCGSAGMFIQSVEFIEAHATGNGNGSRARAR
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEE
ISIYGQELNYTTWRLAKMNLAIRGIDGRIEQGDTFRNDRFPDLKADYILANPPFNMKEWG
EEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCC
GEQLRNDKRWQYGIPPVGNANFAWVQHIVHHLAPAGVAGFVLANGSMSSNQSGEGEIRRK
CHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCCHHHHHHH
LIEADLVDCMVALPGQLFYSTQIPACLWFLARNRNNGKFRDRRKQILFIDARRLGRMVDR
HHHHHHHHHHHHCCCHHEECCCHHHHHHHHHHCCCCCCHHHHCCEEEEEEHHHHHHHHHH
IHRELTDEEIERIACTYHAWRGESDAGEYRDIPGFCKSASLEDVRKHGYVLTPGRYVGSE
HHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCHHHHHHCCEEECCCHHHCCH
VREDDDEPFAEKMQWLVAQLREQQAEAAKLDEAIVANLQELGFWEQKR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]