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The map label for this gene is rsbRA [H]

Identifier: 222525190

GI number: 222525190

Start: 2447479

End: 2448507

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_1929

Alternate gene names: 222525190

Gene position: 2447479-2448507 (Clockwise)

Preceding gene: 222525189

Following gene: 222525191

Centisome position: 46.45

GC content: 55.39

Gene sequence:

>1029_bases
ATGCAAACCTCACAGTCGCTCCTCGATCAGTTTTTTCGCCAGATTGCACGCAGTATTGCCTTGGGGATCGGAGTGATTGC
CGCCGTCGTTGTGCCGATTGAACTCATCAGTTTTGTGCTGACAAACAACACCTTGCTGGCGATTGCGGCGGCGATCAGTA
CAACAATAGGGATCGGGAGCGGGTGTACGGTATTTTTGCTGGATCGGGGACAACCGCTCTGGCAGGGTATTTTGCCTTTT
GCAGTCCTGATCGTGGTTGCCGAGATCATGGTTGCGCTCTGGCTGCCAGAACTCTACGTTTCTGCAGCGCCGTTTATTGT
GGTTGCGATTCTGCTGGCCAGCCTGATCAATCGGCGGGTATTTACTATTAGCGTTCTGGTGATCTGTATTGTGGTAACGG
TGGTGCTGCTGCTCATCAGTCAACCGGCTCCTGAAGCGAAAATTCCTGCCCCGATGTTTAGCTTTTTGCAGGCCAGCAGT
CTTGCAGCGCTGTTTGTTGCGGTCTGGATATTCCTTGATCGGATTATCGCCGCGCAGATGCAGGCGTTGCAGATCGCCGA
TCAGCGGGCCGACGATGCAGAAGCGGCCCGTCAACAAACCGAACTGGCACGTCAGGAGGTTGAACGACGGGCCAGCGAAC
AACAACGTCTGCTTGAACTGGTAGCAGTACTTGAACTGCCGATTTTGACGATAGATGATCGGGTGCTGCTGGCACCGTTG
GTCGGTAACCTCGACAGCCGACGGGCCGATGCGTTACGGCAGCGGGTGCTTGAGCGGCTCGCCGAACTGCGTGCTCATAC
AGTTATCATTGACATTACCGGTATTACGGTGATAGATACTGCGGTGGCGAAGGCGTTGATCGACACGGCTACCGCGATCC
GTCTGCTCGGTGCGCGCACGATTATCAGTGGGATTCGTCCGACAGTCGCGCAGACGCTGGTTCATCTTAACACTGGTCTC
CACGAGATCACGACTGCTCCCAATCCTGAAGCGGCGCTTAGACTTGCCCGTCCGGCGGTGATGATCTGA

Upstream 100 bases:

>100_bases
CGCGCCATCAGCATCGTTTGGTGCGGGCAGATTTGCCATTGATTCGGTGGCTGATGAACTGCAACCTGCTCCCGACCCGT
AGTGTGGCAATGGAGGAAGT

Downstream 100 bases:

>100_bases
AGTCTGCGGTCTTCGTTAGGTGGAAAACGGCGCAAACATTGTTGGGTGGAAAACCCGCAATGTTTGCGCCAGACAGACGC
CACGTTGGTCTATGGTTTTC

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQTSQSLLDQFFRQIARSIALGIGVIAAVVVPIELISFVLTNNTLLAIAAAISTTIGIGSGCTVFLLDRGQPLWQGILPF
AVLIVVAEIMVALWLPELYVSAAPFIVVAILLASLINRRVFTISVLVICIVVTVVLLLISQPAPEAKIPAPMFSFLQASS
LAALFVAVWIFLDRIIAAQMQALQIADQRADDAEAARQQTELARQEVERRASEQQRLLELVAVLELPILTIDDRVLLAPL
VGNLDSRRADALRQRVLERLAELRAHTVIIDITGITVIDTAVAKALIDTATAIRLLGARTIISGIRPTVAQTLVHLNTGL
HEITTAPNPEAALRLARPAVMI

Sequences:

>Translated_342_residues
MQTSQSLLDQFFRQIARSIALGIGVIAAVVVPIELISFVLTNNTLLAIAAAISTTIGIGSGCTVFLLDRGQPLWQGILPF
AVLIVVAEIMVALWLPELYVSAAPFIVVAILLASLINRRVFTISVLVICIVVTVVLLLISQPAPEAKIPAPMFSFLQASS
LAALFVAVWIFLDRIIAAQMQALQIADQRADDAEAARQQTELARQEVERRASEQQRLLELVAVLELPILTIDDRVLLAPL
VGNLDSRRADALRQRVLERLAELRAHTVIIDITGITVIDTAVAKALIDTATAIRLLGARTIISGIRPTVAQTLVHLNTGL
HEITTAPNPEAALRLARPAVMI
>Mature_342_residues
MQTSQSLLDQFFRQIARSIALGIGVIAAVVVPIELISFVLTNNTLLAIAAAISTTIGIGSGCTVFLLDRGQPLWQGILPF
AVLIVVAEIMVALWLPELYVSAAPFIVVAILLASLINRRVFTISVLVICIVVTVVLLLISQPAPEAKIPAPMFSFLQASS
LAALFVAVWIFLDRIIAAQMQALQIADQRADDAEAARQQTELARQEVERRASEQQRLLELVAVLELPILTIDDRVLLAPL
VGNLDSRRADALRQRVLERLAELRAHTVIIDITGITVIDTAVAKALIDTATAIRLLGARTIISGIRPTVAQTLVHLNTGL
HEITTAPNPEAALRLARPAVMI

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 36944; Mature: 36944

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSQSLLDQFFRQIARSIALGIGVIAAVVVPIELISFVLTNNTLLAIAAAISTTIGIGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
GCTVFLLDRGQPLWQGILPFAVLIVVAEIMVALWLPELYVSAAPFIVVAILLASLINRRV
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTISVLVICIVVTVVLLLISQPAPEAKIPAPMFSFLQASSLAALFVAVWIFLDRIIAAQM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALQIADQRADDAEAARQQTELARQEVERRASEQQRLLELVAVLELPILTIDDRVLLAPL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHH
VGNLDSRRADALRQRVLERLAELRAHTVIIDITGITVIDTAVAKALIDTATAIRLLGART
HCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IISGIRPTVAQTLVHLNTGLHEITTAPNPEAALRLARPAVMI
HHHCCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MQTSQSLLDQFFRQIARSIALGIGVIAAVVVPIELISFVLTNNTLLAIAAAISTTIGIGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
GCTVFLLDRGQPLWQGILPFAVLIVVAEIMVALWLPELYVSAAPFIVVAILLASLINRRV
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTISVLVICIVVTVVLLLISQPAPEAKIPAPMFSFLQASSLAALFVAVWIFLDRIIAAQM
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALQIADQRADDAEAARQQTELARQEVERRASEQQRLLELVAVLELPILTIDDRVLLAPL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHH
VGNLDSRRADALRQRVLERLAELRAHTVIIDITGITVIDTAVAKALIDTATAIRLLGART
HCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IISGIRPTVAQTLVHLNTGLHEITTAPNPEAALRLARPAVMI
HHHCCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]