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The map label for this gene is sasA [H]

Identifier: 222525184

GI number: 222525184

Start: 2437561

End: 2438820

Strand: Direct

Name: sasA [H]

Synonym: Chy400_1923

Alternate gene names: 222525184

Gene position: 2437561-2438820 (Clockwise)

Preceding gene: 222525183

Following gene: 222525187

Centisome position: 46.26

GC content: 55.4

Gene sequence:

>1260_bases
GTGGGGGGGCGCAATCAACGTGAACTTGGTGGAAGGCAGGCAGAGAAGACGACGCCAGATATTCTGGAGCTACGCGCCTG
TCTTCGGATGGGGGTAGCAGGCGGCTATACCCCAGCGGCTCTTATTCAACTGGCACAGGCATTAAGCTATGCCACACTGA
GCGAAGGCGGTTCGGTGTTAGTGGCAGGTGCCGGTGGTGGTCATTGGGCAGATCTGGCACTCCAGGATATCCATCTACCG
GTTCAGCGCAGCAATCTGGTTACGCGCGGCAAAGGGGTGGCGCTTATCGGTTTAGGACCACGCTATGGTTACGCATTGGC
CGCGATCCCGATGGAACCACTCGAAGGCGATGCCGATTTGCAGTTGCACGATGCACATTGGAGTTGTGCGCCAGAAGATT
TGCTGGCAATTGGTGAATTGCTCGATGGGGCCATTCCAATGATGCAGCGCGCTGCACTCCTGCGACTCCAACCTCCACCA
TCCAGCATCCTCTTGCAGATTGCTAACCAGGCACTCGATTTTGCGGCACGCCAACATATCACGCTCGCCCTGGCCAACCG
CTCTCTGAGCGAGCGTTTACGGAACCACGAGGATCAAACGCGCATGGTCGTACACGATATGCGGGCACCGCTGCATACGC
TGCTGATTAGTCTGAAAGCACTTGAGCGACAGGGGTTTGATGCCGGTGCTCGCCAGGAGTTGCTGGAAGTTGCCCGGGAA
AGTTCCAATTATCTGCTTGGCCTTATCGATACCGTGCTTGATACGGCGCGTCTGGAGACCAGTAGCTGGGCTTTGCAATT
ACAGCCGACCAATCTGGTTACTCTGATTAAGACGGTGTGTGAACCGTTCCGACAACTGGCGCATCCCGATCAACCGACAG
TACGGGTGGAAATACCGGTAGAGTTGCCGACAATTGTGCTGGATAGCCATCTCATTGAGCGGGTGATTGCCAATCTGGTC
TCGAATGCGATCAAGTTTACACCAGCAGGTGGTGAAGTCAGGATCATGGCTCAGCTCATCAACGATGGTCATACGGTTGA
GATTCGGGTCAGTGATACCGGTTATGGGATACCACCCGAAGCGCAACATCATATCTTTGAGCGCTTCTATCAGGCTCGCG
AACATGATCGGCGCCGTGGTACCGGGTTGGGTCTCTATTTCTGTCGGCTTGCTATCGAAGCGCACGGTGGCAGCATTGCG
TTAGAGAGTGAAGTAGGGCGCGGGAGTACGTTTATTGTGCAGTTGCCGGTGGGAGAGTAG

Upstream 100 bases:

>100_bases
GGAGAATTTCGACCGTCAACTCGATCTCTTTAATCAGATGCTTAACAGCCTCGTAATAGGGTAGTTCAGGCCAGACTACG
CAGCGAGGAAGGAACGAACC

Downstream 100 bases:

>100_bases
GTTGGTGGGGAGGAGGAAGTAGGAGATAGGAGATAGGAGATAGGAAATAGGGGATAGGGGGATAGGAAGTAGATTAGGTA
GGGAAAGTGGGGTATTCCTG

Product: histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MGGRNQRELGGRQAEKTTPDILELRACLRMGVAGGYTPAALIQLAQALSYATLSEGGSVLVAGAGGGHWADLALQDIHLP
VQRSNLVTRGKGVALIGLGPRYGYALAAIPMEPLEGDADLQLHDAHWSCAPEDLLAIGELLDGAIPMMQRAALLRLQPPP
SSILLQIANQALDFAARQHITLALANRSLSERLRNHEDQTRMVVHDMRAPLHTLLISLKALERQGFDAGARQELLEVARE
SSNYLLGLIDTVLDTARLETSSWALQLQPTNLVTLIKTVCEPFRQLAHPDQPTVRVEIPVELPTIVLDSHLIERVIANLV
SNAIKFTPAGGEVRIMAQLINDGHTVEIRVSDTGYGIPPEAQHHIFERFYQAREHDRRRGTGLGLYFCRLAIEAHGGSIA
LESEVGRGSTFIVQLPVGE

Sequences:

>Translated_419_residues
MGGRNQRELGGRQAEKTTPDILELRACLRMGVAGGYTPAALIQLAQALSYATLSEGGSVLVAGAGGGHWADLALQDIHLP
VQRSNLVTRGKGVALIGLGPRYGYALAAIPMEPLEGDADLQLHDAHWSCAPEDLLAIGELLDGAIPMMQRAALLRLQPPP
SSILLQIANQALDFAARQHITLALANRSLSERLRNHEDQTRMVVHDMRAPLHTLLISLKALERQGFDAGARQELLEVARE
SSNYLLGLIDTVLDTARLETSSWALQLQPTNLVTLIKTVCEPFRQLAHPDQPTVRVEIPVELPTIVLDSHLIERVIANLV
SNAIKFTPAGGEVRIMAQLINDGHTVEIRVSDTGYGIPPEAQHHIFERFYQAREHDRRRGTGLGLYFCRLAIEAHGGSIA
LESEVGRGSTFIVQLPVGE
>Mature_418_residues
GGRNQRELGGRQAEKTTPDILELRACLRMGVAGGYTPAALIQLAQALSYATLSEGGSVLVAGAGGGHWADLALQDIHLPV
QRSNLVTRGKGVALIGLGPRYGYALAAIPMEPLEGDADLQLHDAHWSCAPEDLLAIGELLDGAIPMMQRAALLRLQPPPS
SILLQIANQALDFAARQHITLALANRSLSERLRNHEDQTRMVVHDMRAPLHTLLISLKALERQGFDAGARQELLEVARES
SNYLLGLIDTVLDTARLETSSWALQLQPTNLVTLIKTVCEPFRQLAHPDQPTVRVEIPVELPTIVLDSHLIERVIANLVS
NAIKFTPAGGEVRIMAQLINDGHTVEIRVSDTGYGIPPEAQHHIFERFYQAREHDRRRGTGLGLYFCRLAIEAHGGSIAL
ESEVGRGSTFIVQLPVGE

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=219, Percent_Identity=31.5068493150685, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=31.25, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI145693157, Length=218, Percent_Identity=31.1926605504587, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=28.2442748091603, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=28.7037037037037, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=26.5060240963855, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786783, Length=216, Percent_Identity=24.537037037037, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=28.0487804878049, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=30.1652892561983, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=173, Percent_Identity=31.2138728323699, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=216, Percent_Identity=27.3148148148148, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=30.4147465437788, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=30.6034482758621, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 45601; Mature: 45470

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRNQRELGGRQAEKTTPDILELRACLRMGVAGGYTPAALIQLAQALSYATLSEGGSVL
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
VAGAGGGHWADLALQDIHLPVQRSNLVTRGKGVALIGLGPRYGYALAAIPMEPLEGDADL
EEECCCCCHHHHHHHHHCCCHHHCCCEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCE
QLHDAHWSCAPEDLLAIGELLDGAIPMMQRAALLRLQPPPSSILLQIANQALDFAARQHI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHE
TLALANRSLSERLRNHEDQTRMVVHDMRAPLHTLLISLKALERQGFDAGARQELLEVARE
EEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
SSNYLLGLIDTVLDTARLETSSWALQLQPTNLVTLIKTVCEPFRQLAHPDQPTVRVEIPV
CCCCEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
ELPTIVLDSHLIERVIANLVSNAIKFTPAGGEVRIMAQLINDGHTVEIRVSDTGYGIPPE
CCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEHHCCCCEEEEEECCCCCCCCCH
AQHHIFERFYQAREHDRRRGTGLGLYFCRLAIEAHGGSIALESEVGRGSTFIVQLPVGE
HHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEEECCCEEEEECCCCCCCEEEEEECCCC
>Mature Secondary Structure 
GGRNQRELGGRQAEKTTPDILELRACLRMGVAGGYTPAALIQLAQALSYATLSEGGSVL
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
VAGAGGGHWADLALQDIHLPVQRSNLVTRGKGVALIGLGPRYGYALAAIPMEPLEGDADL
EEECCCCCHHHHHHHHHCCCHHHCCCEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCE
QLHDAHWSCAPEDLLAIGELLDGAIPMMQRAALLRLQPPPSSILLQIANQALDFAARQHI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHE
TLALANRSLSERLRNHEDQTRMVVHDMRAPLHTLLISLKALERQGFDAGARQELLEVARE
EEEECCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHC
SSNYLLGLIDTVLDTARLETSSWALQLQPTNLVTLIKTVCEPFRQLAHPDQPTVRVEIPV
CCCCEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
ELPTIVLDSHLIERVIANLVSNAIKFTPAGGEVRIMAQLINDGHTVEIRVSDTGYGIPPE
CCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEHHCCCCEEEEEECCCCCCCCCH
AQHHIFERFYQAREHDRRRGTGLGLYFCRLAIEAHGGSIALESEVGRGSTFIVQLPVGE
HHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEEECCCEEEEECCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA