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The map label for this gene is nhaR [H]

Identifier: 222525187

GI number: 222525187

Start: 2444166

End: 2445047

Strand: Direct

Name: nhaR [H]

Synonym: Chy400_1926

Alternate gene names: 222525187

Gene position: 2444166-2445047 (Clockwise)

Preceding gene: 222525184

Following gene: 222525188

Centisome position: 46.39

GC content: 54.99

Gene sequence:

>882_bases
ATGCTGAACTACCATCACCTCCGATATTTCTGGATCGTGGCTCATGAAGGTAATCTGACGCGGGCCGCTCGTAAACACAA
CATTGCCCAGTCTGCGCTTTCGATGCAGATCAGCGCGCTCGAAGAGTATCTGGGCCAGCCACTGTTTGAGCGTGCCGGTC
GTCGTCTGGTGTTGACCGAAGCCGGTCACATTGCGTTGGACTTTGCCGACGCGATTTTTGCCAAAGGTGACGAACTGCTC
GGTACCTTTGGCCGGCTGGCAGAAGCACACCAAAAGGTCTTGCGGGTTGGTGCGCTGGCAACCTTATCGCGCAATTTTCA
AGTGGGGTTTTTGCGTCCTTTGTTTGCCGATCCCGAAATTACCGTGATTGTCCGTTCCGGCACGCTGGACGAGCTACTTG
GGAGTCTGAAGCTCTACGATCTGGATATTGTGCTGGCAACCGGTGTTCCCAATCGCGACCACGCTACGCCGTGGATTGTC
CATATCATCGATACGCAACCGGTAGGGCTGATTGGACAGCCGCGATCAGATCGGTATCAGCAACCTCTGGAGGTATTGCT
CCAGCGTGAACCGCTTATCGTGCCATCACCGGAGTCTACGATTCGCACCGGCTTTGATGCGCTTGTTCATCGGCTAGGTA
TTCGCCCTCGTATCGTGGCTGAAATCGACGATATGGCGATGATGCGTCTTGTGGCGCGTGAACACAACGGATTAGCAGTC
ATTCCACCAATCGTCGTGACAGATGAGTTGCGCAGCGGGATGCTGGTGGAATACGCTGAACTGCCAGAGCTTGTCGAGAC
CTTCTGTGCGATTACCATGCCACGGCGCTTTCCCAATCCTCTGCTGCGGTTGGTGCTACCCGGACACACAACACCGGAAT
AA

Upstream 100 bases:

>100_bases
TTGCCACCTTCATCACCGGCGAATCACCTGCTACCCAGCGGTGGTATATTGGTAGCATCTGGCAAGAACGAGAGCATGTA
CCAATACGAGACCTGGCAAT

Downstream 100 bases:

>100_bases
CTGTCATTCTGACCGATTATCATTAACCCAAGTTGCTACCTTTGTCACCACAGAGGCACGGAGGACACAGAGGATGGGGA
TAACCGGAATTGCTACCCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MLNYHHLRYFWIVAHEGNLTRAARKHNIAQSALSMQISALEEYLGQPLFERAGRRLVLTEAGHIALDFADAIFAKGDELL
GTFGRLAEAHQKVLRVGALATLSRNFQVGFLRPLFADPEITVIVRSGTLDELLGSLKLYDLDIVLATGVPNRDHATPWIV
HIIDTQPVGLIGQPRSDRYQQPLEVLLQREPLIVPSPESTIRTGFDALVHRLGIRPRIVAEIDDMAMMRLVAREHNGLAV
IPPIVVTDELRSGMLVEYAELPELVETFCAITMPRRFPNPLLRLVLPGHTTPE

Sequences:

>Translated_293_residues
MLNYHHLRYFWIVAHEGNLTRAARKHNIAQSALSMQISALEEYLGQPLFERAGRRLVLTEAGHIALDFADAIFAKGDELL
GTFGRLAEAHQKVLRVGALATLSRNFQVGFLRPLFADPEITVIVRSGTLDELLGSLKLYDLDIVLATGVPNRDHATPWIV
HIIDTQPVGLIGQPRSDRYQQPLEVLLQREPLIVPSPESTIRTGFDALVHRLGIRPRIVAEIDDMAMMRLVAREHNGLAV
IPPIVVTDELRSGMLVEYAELPELVETFCAITMPRRFPNPLLRLVLPGHTTPE
>Mature_293_residues
MLNYHHLRYFWIVAHEGNLTRAARKHNIAQSALSMQISALEEYLGQPLFERAGRRLVLTEAGHIALDFADAIFAKGDELL
GTFGRLAEAHQKVLRVGALATLSRNFQVGFLRPLFADPEITVIVRSGTLDELLGSLKLYDLDIVLATGVPNRDHATPWIV
HIIDTQPVGLIGQPRSDRYQQPLEVLLQREPLIVPSPESTIRTGFDALVHRLGIRPRIVAEIDDMAMMRLVAREHNGLAV
IPPIVVTDELRSGMLVEYAELPELVETFCAITMPRRFPNPLLRLVLPGHTTPE

Specific function: Plays a role in the positive regulation of nhaA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=296, Percent_Identity=26.0135135135135, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI157672245, Length=275, Percent_Identity=29.0909090909091, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87081904, Length=262, Percent_Identity=29.3893129770992, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32770; Mature: 32770

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYHHLRYFWIVAHEGNLTRAARKHNIAQSALSMQISALEEYLGQPLFERAGRRLVLTE
CCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEE
AGHIALDFADAIFAKGDELLGTFGRLAEAHQKVLRVGALATLSRNFQVGFLRPLFADPEI
CCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCE
TVIVRSGTLDELLGSLKLYDLDIVLATGVPNRDHATPWIVHIIDTQPVGLIGQPRSDRYQ
EEEEECCCHHHHHHCCEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHH
QPLEVLLQREPLIVPSPESTIRTGFDALVHRLGIRPRIVAEIDDMAMMRLVAREHNGLAV
HHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEE
IPPIVVTDELRSGMLVEYAELPELVETFCAITMPRRFPNPLLRLVLPGHTTPE
ECCEEEEHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MLNYHHLRYFWIVAHEGNLTRAARKHNIAQSALSMQISALEEYLGQPLFERAGRRLVLTE
CCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEE
AGHIALDFADAIFAKGDELLGTFGRLAEAHQKVLRVGALATLSRNFQVGFLRPLFADPEI
CCCEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCE
TVIVRSGTLDELLGSLKLYDLDIVLATGVPNRDHATPWIVHIIDTQPVGLIGQPRSDRYQ
EEEEECCCHHHHHHCCEEEEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHH
QPLEVLLQREPLIVPSPESTIRTGFDALVHRLGIRPRIVAEIDDMAMMRLVAREHNGLAV
HHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCEEE
IPPIVVTDELRSGMLVEYAELPELVETFCAITMPRRFPNPLLRLVLPGHTTPE
ECCEEEEHHHHCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2429258; 1630901; 9278503; 3413113; 1316901; 8168494 [H]