Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 222525158

GI number: 222525158

Start: 2398996

End: 2400015

Strand: Direct

Name: trpD [H]

Synonym: Chy400_1896

Alternate gene names: 222525158

Gene position: 2398996-2400015 (Clockwise)

Preceding gene: 222525157

Following gene: 222525159

Centisome position: 45.53

GC content: 60.88

Gene sequence:

>1020_bases
ATGAACATCCGCGAAGCGATTGCGGCAGTGGTCGCCCGGCGAGATTTGACCCAGGCTGAAGCAGCGAGTGTGATGGAAGA
GATTATGAGCGGTACGGCCACGCCGGCCCAGATCGGGGCGTTTCTGACCGCTTTGCATATGAAGGGTGAGACGGACGCTG
AGATCGCCGGTATGGCGGCGGTGATGCGTGAAAAGGCAACCCACGTCTATTTTGATGGACCGGTGATTGATACCTGCGGT
ACCGGTGGCGATGGGGCGCATACGTTTAACATTAGCACGACAGCAGCATTTGTGGCTGCCGGTGCCGGGTTGACGGTGGC
AAAGCATGGGAATCGCGCTATGTCGAGTGTGTGCGGCAGCGCCGATGTGCTTGAGGGTTTAGGAGTGCAGATCGAACTCG
ATGCCGAGGGTGTCGCCCGCTGTTTGCGCGAGGCCGGGATCGGGTTTATGTTTGCCCCTAAGTTCCATCCGGCTATGCGG
TTTGCCGGGCCGGTACGCCGCGAGATTGGCATTCGCACGGTGTTCAATATTCTCGGCCCGCTGACCAACCCGGCTCGCGC
CCGTTATCAGGTGCTGGGCGTCGCCAGTGCTGCCCTGGCCGAAAAACTGGCTTACGCGCTCAGCCGGCTTGATACGGTGC
ATGCTCTGGTGGTTCACGGTGATGGTGGTGTCGATGAGCTGACGCTATCCGGGCCGAATCTGATTTTTGACGTTCGCGCC
GGTCAGGCACCCCGGCAGATGCTGGTTGCGCCCGAAGATGTCGGGCTGCCCAGAGCACCCCAGGATGCGCTGCGCGGCGG
TGATGTGGCGTACAATGTCGCAATTGTACGCGCCATTCTGAGTGGCGAAGAACATGGGCCGCGTCGCGATGTTGTGCTGT
TCAATGCGGCGGCAGCGATGGTCGCCGGTGATCTGGCCCCCGATCTGGCTACCGGTGTGGCGATGGCCCGTCATAGTATC
GACAGTGGCCGAGCGCTGGAGCGGTTGAACCAGATGATTGCTGTCAGTCGTGGCGAATGA

Upstream 100 bases:

>100_bases
GCTACCAGAGTCTGCTTCTCTTAATCCCCCACATTGACCACAACGCATCGGATCGCTACAATACAAACGCAGTGCGCATG
ACGAGCCAAAGGAGCTGATG

Downstream 100 bases:

>100_bases
AGGCGACGGTCGTGGTATGGCTCAGGATGTACGACTGACACGGTTACGTCGTCGTAGATTTGCGCTCTGGCGCCTGATAG
TTGCGAATCTGCTTGACGAT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNIREAIAAVVARRDLTQAEAASVMEEIMSGTATPAQIGAFLTALHMKGETDAEIAGMAAVMREKATHVYFDGPVIDTCG
TGGDGAHTFNISTTAAFVAAGAGLTVAKHGNRAMSSVCGSADVLEGLGVQIELDAEGVARCLREAGIGFMFAPKFHPAMR
FAGPVRREIGIRTVFNILGPLTNPARARYQVLGVASAALAEKLAYALSRLDTVHALVVHGDGGVDELTLSGPNLIFDVRA
GQAPRQMLVAPEDVGLPRAPQDALRGGDVAYNVAIVRAILSGEEHGPRRDVVLFNAAAAMVAGDLAPDLATGVAMARHSI
DSGRALERLNQMIAVSRGE

Sequences:

>Translated_339_residues
MNIREAIAAVVARRDLTQAEAASVMEEIMSGTATPAQIGAFLTALHMKGETDAEIAGMAAVMREKATHVYFDGPVIDTCG
TGGDGAHTFNISTTAAFVAAGAGLTVAKHGNRAMSSVCGSADVLEGLGVQIELDAEGVARCLREAGIGFMFAPKFHPAMR
FAGPVRREIGIRTVFNILGPLTNPARARYQVLGVASAALAEKLAYALSRLDTVHALVVHGDGGVDELTLSGPNLIFDVRA
GQAPRQMLVAPEDVGLPRAPQDALRGGDVAYNVAIVRAILSGEEHGPRRDVVLFNAAAAMVAGDLAPDLATGVAMARHSI
DSGRALERLNQMIAVSRGE
>Mature_339_residues
MNIREAIAAVVARRDLTQAEAASVMEEIMSGTATPAQIGAFLTALHMKGETDAEIAGMAAVMREKATHVYFDGPVIDTCG
TGGDGAHTFNISTTAAFVAAGAGLTVAKHGNRAMSSVCGSADVLEGLGVQIELDAEGVARCLREAGIGFMFAPKFHPAMR
FAGPVRREIGIRTVFNILGPLTNPARARYQVLGVASAALAEKLAYALSRLDTVHALVVHGDGGVDELTLSGPNLIFDVRA
GQAPRQMLVAPEDVGLPRAPQDALRGGDVAYNVAIVRAILSGEEHGPRRDVVLFNAAAAMVAGDLAPDLATGVAMARHSI
DSGRALERLNQMIAVSRGE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=273, Percent_Identity=39.9267399267399, Blast_Score=179, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6320561, Length=355, Percent_Identity=30.4225352112676, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 35285; Mature: 35285

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIREAIAAVVARRDLTQAEAASVMEEIMSGTATPAQIGAFLTALHMKGETDAEIAGMAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VMREKATHVYFDGPVIDTCGTGGDGAHTFNISTTAAFVAAGAGLTVAKHGNRAMSSVCGS
HHHHCCCEEEECCCEEECCCCCCCCCEEEECHHHHHHHHCCCCEEEEECCCHHHHHHCCC
ADVLEGLGVQIELDAEGVARCLREAGIGFMFAPKFHPAMRFAGPVRREIGIRTVFNILGP
HHHHHCCCCEEEECHHHHHHHHHHCCCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCC
LTNPARARYQVLGVASAALAEKLAYALSRLDTVHALVVHGDGGVDELTLSGPNLIFDVRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEECCCCEEEEECC
GQAPRQMLVAPEDVGLPRAPQDALRGGDVAYNVAIVRAILSGEEHGPRRDVVLFNAAAAM
CCCCHHEEECCHHCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHH
VAGDLAPDLATGVAMARHSIDSGRALERLNQMIAVSRGE
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNIREAIAAVVARRDLTQAEAASVMEEIMSGTATPAQIGAFLTALHMKGETDAEIAGMAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
VMREKATHVYFDGPVIDTCGTGGDGAHTFNISTTAAFVAAGAGLTVAKHGNRAMSSVCGS
HHHHCCCEEEECCCEEECCCCCCCCCEEEECHHHHHHHHCCCCEEEEECCCHHHHHHCCC
ADVLEGLGVQIELDAEGVARCLREAGIGFMFAPKFHPAMRFAGPVRREIGIRTVFNILGP
HHHHHCCCCEEEECHHHHHHHHHHCCCCEEECCCCCHHHHHCCHHHHHHHHHHHHHHHCC
LTNPARARYQVLGVASAALAEKLAYALSRLDTVHALVVHGDGGVDELTLSGPNLIFDVRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEECCCCEEEEECC
GQAPRQMLVAPEDVGLPRAPQDALRGGDVAYNVAIVRAILSGEEHGPRRDVVLFNAAAAM
CCCCHHEEECCHHCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHH
VAGDLAPDLATGVAMARHSIDSGRALERLNQMIAVSRGE
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA