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The map label for this gene is iorA [H]

Identifier: 222525132

GI number: 222525132

Start: 2363368

End: 2363835

Strand: Direct

Name: iorA [H]

Synonym: Chy400_1870

Alternate gene names: 222525132

Gene position: 2363368-2363835 (Clockwise)

Preceding gene: 222525126

Following gene: 222525133

Centisome position: 44.85

GC content: 59.62

Gene sequence:

>468_bases
ATGGAATTGACGATCAACGGTCAACGTTACACGGTCGCTGATGAACCGGCCCGTCCGCTGTTGTACGTGTTGCGCGATGA
GCTGGGGCTGACGGGAACCAAATTTGGGTGTGGCGCCGGTATCTGCGGTGCATGTACCGTCCATGTGAATGGCCAGGCCA
CTCGCAGTTGTCAGACGATGATCGCGACGCTGGCCGGGGCGCAGATTACGACCATCGAGGGATTGGCCGATGGTGAGCGT
TTGCATCCGGTACAACAGGCATTTCTTGAGCTACAGGTACCGCAGTGTGGCTGGTGTATGAGCGGGCAGATGATGACCGC
AGCCGCATTGCTGGCCGCCAACCCTACGCCGACGCACGAAGAGATGATTGCGGCGATGCGTTATAACTACTGTCGTTGTG
GCACCTATGCCCGGATCGGGCGAGCAGTGATGCGGGCGGCAGAGCTGATGAAGGAGCGGGCGGGATGA

Upstream 100 bases:

>100_bases
CAAGCGCATATCGGTTACTAACGCCCTTGCCGTGACTCTGCCGTGCACTGGTAGTATACTATGAACAGGTATTGCACGAC
AATTGCACCAGAGGATGATT

Downstream 100 bases:

>100_bases
AGCAGGATACATCACCAAAACGCTGGCGGATGACGCGACGGGGTTTTCTGATCGGGATGGGGCTGGCTGGCGGTGGGTTG
GCGCTGGGCGCAATCTTTGG

Product: (2Fe-2S)-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MELTINGQRYTVADEPARPLLYVLRDELGLTGTKFGCGAGICGACTVHVNGQATRSCQTMIATLAGAQITTIEGLADGER
LHPVQQAFLELQVPQCGWCMSGQMMTAAALLAANPTPTHEEMIAAMRYNYCRCGTYARIGRAVMRAAELMKERAG

Sequences:

>Translated_155_residues
MELTINGQRYTVADEPARPLLYVLRDELGLTGTKFGCGAGICGACTVHVNGQATRSCQTMIATLAGAQITTIEGLADGER
LHPVQQAFLELQVPQCGWCMSGQMMTAAALLAANPTPTHEEMIAAMRYNYCRCGTYARIGRAVMRAAELMKERAG
>Mature_155_residues
MELTINGQRYTVADEPARPLLYVLRDELGLTGTKFGCGAGICGACTVHVNGQATRSCQTMIATLAGAQITTIEGLADGER
LHPVQQAFLELQVPQCGWCMSGQMMTAAALLAANPTPTHEEMIAAMRYNYCRCGTYARIGRAVMRAAELMKERAG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=147, Percent_Identity=38.0952380952381, Blast_Score=74, Evalue=4e-14,
Organism=Homo sapiens, GI71773480, Length=95, Percent_Identity=34.7368421052632, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786480, Length=166, Percent_Identity=39.7590361445783, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1789232, Length=146, Percent_Identity=39.7260273972603, Blast_Score=91, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=38.9261744966443, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=139, Percent_Identity=36.6906474820144, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=139, Percent_Identity=35.2517985611511, Blast_Score=99, Evalue=8e-22,
Organism=Drosophila melanogaster, GI17737937, Length=149, Percent_Identity=36.9127516778523, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647201, Length=146, Percent_Identity=36.3013698630137, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=34.375, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647199, Length=147, Percent_Identity=34.0136054421769, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24647195, Length=156, Percent_Identity=33.974358974359, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647197, Length=156, Percent_Identity=33.974358974359, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16672; Mature: 16672

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
11.0 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
11.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTINGQRYTVADEPARPLLYVLRDELGLTGTKFGCGAGICGACTVHVNGQATRSCQTM
CEEEECCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
IATLAGAQITTIEGLADGERLHPVQQAFLELQVPQCGWCMSGQMMTAAALLAANPTPTHE
HHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHH
EMIAAMRYNYCRCGTYARIGRAVMRAAELMKERAG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELTINGQRYTVADEPARPLLYVLRDELGLTGTKFGCGAGICGACTVHVNGQATRSCQTM
CEEEECCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHH
IATLAGAQITTIEGLADGERLHPVQQAFLELQVPQCGWCMSGQMMTAAALLAANPTPTHE
HHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHH
EMIAAMRYNYCRCGTYARIGRAVMRAAELMKERAG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]