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The map label for this gene is iorB [H]

Identifier: 222525133

GI number: 222525133

Start: 2363832

End: 2365997

Strand: Direct

Name: iorB [H]

Synonym: Chy400_1871

Alternate gene names: 222525133

Gene position: 2363832-2365997 (Clockwise)

Preceding gene: 222525132

Following gene: 222525134

Centisome position: 44.86

GC content: 62.88

Gene sequence:

>2166_bases
ATGAAGCAGGATACATCACCAAAACGCTGGCGGATGACGCGACGGGGTTTTCTGATCGGGATGGGGCTGGCTGGCGGTGG
GTTGGCGCTGGGCGCAATCTTTGGTCTACCGGCGGCACGGCTGGCGCTGGCCGACATGTTCGCTGATGTGATCAATATTC
CGTCGAATATGCCGCGCGAACCGCAGCTCTGGTTCACGATCCAGCCCGATGGCCGTGTGACGATGACGATGCCCAAGGTG
GAGATGGGGCAGGGTGTGCATACGGCGCTGGCTCAGATTGCGGCTGAGGAGCTGGGTGTGAGTTGGGAACAGATGCAGGT
GGTGCAGAGCAGTTCGCTCGGCCCGGTTGCCGATGGTGCCGGTACCAGTGCTTCCTATTCGGTGATCTCACTCTTCCCGT
TGCTCCGCGAGATGGCGGCGACGTTGCGCGAGATGTTGCGCACCGCCGGTGCCGATCAGCTCGGTATTGCACCGGCGCAA
ACCCGAATTGAGCAGGGATTCGTGGTTGATGCCGATCAGCCGGCACGCCGGATCAGTTTCGCTGAACTGGTCGCCCAACC
TCGTAACTGGGAGACTCCCACCGAAGCCGCTCCGCTCACGCCACCTGAGCGCTGGCAGATTATTGGTCAGCCAGTGCCGC
GGCTCGATCTCCCGGCCAAGATTCGTGGGGAAGCGGTGTACGGCTACGACGCTCGGATTGAGGGGATGCTCTACGGCGCT
GTTGCCCGACCACCGCGTCTGGGGGCAAAGCTGCGGCGGGCAGCAGCGGGTACGGCTCGCAACCGACCGGGCGTGGTTGA
GGTGGTGATTCGCGATGGCTTTGCCGGCGTGGTCGCCGAGTCGCGGCTGACGGCGTATGCTGCACTGAACGATCTGGAAC
TGGATTGGGAACTGCCGCCGCCGTTCAATCTGGCAGAGCTTCAAGCCCGGCTCGCAGCGCAGGCCGGATCGGGAACGGTG
ATTCAGCGGCAGGGTGATGCTGCGGCAGCGCTGCGCGGTGCCGGCGTGATTGAGGCAACCTATCAGACTCCTCTGGCTGC
ACACGCCAATCTTGAGCCGCAGGCCGCCCTGGTCGATGTGCAACCGGATCGGGTTCGAGCCTGGGTCAGCACACAATCAC
CGGTGCAGGTTGCGCGCACCATAGCCGAGGTGATCGGTCGTAAGCCGGAGACGGTTGAGGTTACGCCAACCTACCTGGGA
GGCGGATTTGGACGCAAAGTGACCACAACTGTTGCCACCGAAGCGGCACTGTTGTCGGCAGCGGTTGGGCGTCCTGTTCA
CGTTGGCTGGACGCGCACCGAGGAGTTTCGCTACGGGTATCTGCGTCCACCGACCTACGCAACCTTTCGGGCTACCCTCA
CGGACGATGGTCGGATCGCCGCGCTTGTGCAACACCATGTGAGCGGGAACGTGTTGTTTGATCTCTTTCCGCCGCCACTG
CGCTGGCTGTTCGGTAGTGATTTTGGCGGTTGGCGTGGTGCCCGGCTTATCTACGACATTCCCAACCTGGAAGTCAAGGC
GCAAACGGTCGATCTGCCGGTGCCAACCGGCCCCTGGCGGGGGTTGGGTCTACTGGCGAACGTCTTTGCCGTCGAAAGTT
TTATCGATGAACTGGCGGTGGCTGCCGGTAGCGATCCGCTCGATTTTCGCCTGCGGCACCTGCCCGATACTGCGACGGGC
AATCGCTTCCGTGCCGCGTTGGAGGCAGTTGCTGCAATGGCCGGCTGGTACGATCAGCCACCACCTGGCCGGGCGCGGGG
GATTGCCTGTAGTATTGATGCCGGCACAATAGCTGCCCATGTCGCTGAGGTGGGTCTGGTCGAAGGCCGGTTGCGGGTCT
ATCGGGTGTGGGCCGCTGTCGATCCCGGTGTCGCCATCAACCCCGACGGTCTGGCGGCTCAGACCGAGGGCGGCATCATG
ATGGGGCTGAGTGCAGCACTGTTCGAGCAGATTACGATTGCCGATGGGCGGATTGAAGCCGGTAATTTTGATCGCTACCC
GCTCTTGACCATCGCCGATGCGCCAGAGGTGTTTGTGCAGATTCTGCGCAGCGGCGATCAACCGTTTGGCGGTGGTGAAC
CGCCGATGGGGCCGATTGCGGCAGCGGTAGCCAATGCGCTGGCTCGCTTAACCGGTGAACGGCGTCGGCAGTGGCCGTTG
GTGTAG

Upstream 100 bases:

>100_bases
TGATTGCGGCGATGCGTTATAACTACTGTCGTTGTGGCACCTATGCCCGGATCGGGCGAGCAGTGATGCGGGCGGCAGAG
CTGATGAAGGAGCGGGCGGG

Downstream 100 bases:

>100_bases
GGGGGTGGTTAGGAAATAGGATGTAGAAGATAGGATATAGGGTGTAGGATATAAGATATCGTGGGGCTGAAGCTCTTGCT
CACGATGTGCAAGTTCCTGC

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 721

Protein sequence:

>721_residues
MKQDTSPKRWRMTRRGFLIGMGLAGGGLALGAIFGLPAARLALADMFADVINIPSNMPREPQLWFTIQPDGRVTMTMPKV
EMGQGVHTALAQIAAEELGVSWEQMQVVQSSSLGPVADGAGTSASYSVISLFPLLREMAATLREMLRTAGADQLGIAPAQ
TRIEQGFVVDADQPARRISFAELVAQPRNWETPTEAAPLTPPERWQIIGQPVPRLDLPAKIRGEAVYGYDARIEGMLYGA
VARPPRLGAKLRRAAAGTARNRPGVVEVVIRDGFAGVVAESRLTAYAALNDLELDWELPPPFNLAELQARLAAQAGSGTV
IQRQGDAAAALRGAGVIEATYQTPLAAHANLEPQAALVDVQPDRVRAWVSTQSPVQVARTIAEVIGRKPETVEVTPTYLG
GGFGRKVTTTVATEAALLSAAVGRPVHVGWTRTEEFRYGYLRPPTYATFRATLTDDGRIAALVQHHVSGNVLFDLFPPPL
RWLFGSDFGGWRGARLIYDIPNLEVKAQTVDLPVPTGPWRGLGLLANVFAVESFIDELAVAAGSDPLDFRLRHLPDTATG
NRFRAALEAVAAMAGWYDQPPPGRARGIACSIDAGTIAAHVAEVGLVEGRLRVYRVWAAVDPGVAINPDGLAAQTEGGIM
MGLSAALFEQITIADGRIEAGNFDRYPLLTIADAPEVFVQILRSGDQPFGGGEPPMGPIAAAVANALARLTGERRRQWPL
V

Sequences:

>Translated_721_residues
MKQDTSPKRWRMTRRGFLIGMGLAGGGLALGAIFGLPAARLALADMFADVINIPSNMPREPQLWFTIQPDGRVTMTMPKV
EMGQGVHTALAQIAAEELGVSWEQMQVVQSSSLGPVADGAGTSASYSVISLFPLLREMAATLREMLRTAGADQLGIAPAQ
TRIEQGFVVDADQPARRISFAELVAQPRNWETPTEAAPLTPPERWQIIGQPVPRLDLPAKIRGEAVYGYDARIEGMLYGA
VARPPRLGAKLRRAAAGTARNRPGVVEVVIRDGFAGVVAESRLTAYAALNDLELDWELPPPFNLAELQARLAAQAGSGTV
IQRQGDAAAALRGAGVIEATYQTPLAAHANLEPQAALVDVQPDRVRAWVSTQSPVQVARTIAEVIGRKPETVEVTPTYLG
GGFGRKVTTTVATEAALLSAAVGRPVHVGWTRTEEFRYGYLRPPTYATFRATLTDDGRIAALVQHHVSGNVLFDLFPPPL
RWLFGSDFGGWRGARLIYDIPNLEVKAQTVDLPVPTGPWRGLGLLANVFAVESFIDELAVAAGSDPLDFRLRHLPDTATG
NRFRAALEAVAAMAGWYDQPPPGRARGIACSIDAGTIAAHVAEVGLVEGRLRVYRVWAAVDPGVAINPDGLAAQTEGGIM
MGLSAALFEQITIADGRIEAGNFDRYPLLTIADAPEVFVQILRSGDQPFGGGEPPMGPIAAAVANALARLTGERRRQWPL
V
>Mature_721_residues
MKQDTSPKRWRMTRRGFLIGMGLAGGGLALGAIFGLPAARLALADMFADVINIPSNMPREPQLWFTIQPDGRVTMTMPKV
EMGQGVHTALAQIAAEELGVSWEQMQVVQSSSLGPVADGAGTSASYSVISLFPLLREMAATLREMLRTAGADQLGIAPAQ
TRIEQGFVVDADQPARRISFAELVAQPRNWETPTEAAPLTPPERWQIIGQPVPRLDLPAKIRGEAVYGYDARIEGMLYGA
VARPPRLGAKLRRAAAGTARNRPGVVEVVIRDGFAGVVAESRLTAYAALNDLELDWELPPPFNLAELQARLAAQAGSGTV
IQRQGDAAAALRGAGVIEATYQTPLAAHANLEPQAALVDVQPDRVRAWVSTQSPVQVARTIAEVIGRKPETVEVTPTYLG
GGFGRKVTTTVATEAALLSAAVGRPVHVGWTRTEEFRYGYLRPPTYATFRATLTDDGRIAALVQHHVSGNVLFDLFPPPL
RWLFGSDFGGWRGARLIYDIPNLEVKAQTVDLPVPTGPWRGLGLLANVFAVESFIDELAVAAGSDPLDFRLRHLPDTATG
NRFRAALEAVAAMAGWYDQPPPGRARGIACSIDAGTIAAHVAEVGLVEGRLRVYRVWAAVDPGVAINPDGLAAQTEGGIM
MGLSAALFEQITIADGRIEAGNFDRYPLLTIADAPEVFVQILRSGDQPFGGGEPPMGPIAAAVANALARLTGERRRQWPL
V

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789230, Length=396, Percent_Identity=28.2828282828283, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1789246, Length=554, Percent_Identity=22.9241877256318, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786478, Length=390, Percent_Identity=27.4358974358974, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 77186; Mature: 77186

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDTSPKRWRMTRRGFLIGMGLAGGGLALGAIFGLPAARLALADMFADVINIPSNMPRE
CCCCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
PQLWFTIQPDGRVTMTMPKVEMGQGVHTALAQIAAEELGVSWEQMQVVQSSSLGPVADGA
CCEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
GTSASYSVISLFPLLREMAATLREMLRTAGADQLGIAPAQTRIEQGFVVDADQPARRISF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEECCCCCHHHHHH
AELVAQPRNWETPTEAAPLTPPERWQIIGQPVPRLDLPAKIRGEAVYGYDARIEGMLYGA
HHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEECCCCEECEEEEEC
VARPPRLGAKLRRAAAGTARNRPGVVEVVIRDGFAGVVAESRLTAYAALNDLELDWELPP
CCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHEEEECCCCEEEECCCC
PFNLAELQARLAAQAGSGTVIQRQGDAAAALRGAGVIEATYQTPLAAHANLEPQAALVDV
CCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCEEEEECCCCEEECCCCCCCEEEEEC
QPDRVRAWVSTQSPVQVARTIAEVIGRKPETVEVTPTYLGGGFGRKVTTTVATEAALLSA
CHHHEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCEEEHHHHHHHHHHHH
AVGRPVHVGWTRTEEFRYGYLRPPTYATFRATLTDDGRIAALVQHHVSGNVLFDLFPPPL
HCCCCEEECCCCCHHCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHCCCCEEEECCCCHH
RWLFGSDFGGWRGARLIYDIPNLEVKAQTVDLPVPTGPWRGLGLLANVFAVESFIDELAV
HHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAGSDPLDFRLRHLPDTATGNRFRAALEAVAAMAGWYDQPPPGRARGIACSIDAGTIAAH
HCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHH
VAEVGLVEGRLRVYRVWAAVDPGVAINPDGLAAQTEGGIMMGLSAALFEQITIADGRIEA
HHHHHHHCCCEEEEEEEEECCCCCEECCCCCCEECCCCEEEHHHHHHHHHEEEECCEEEC
GNFDRYPLLTIADAPEVFVQILRSGDQPFGGGEPPMGPIAAAVANALARLTGERRRQWPL
CCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
V
C
>Mature Secondary Structure
MKQDTSPKRWRMTRRGFLIGMGLAGGGLALGAIFGLPAARLALADMFADVINIPSNMPRE
CCCCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
PQLWFTIQPDGRVTMTMPKVEMGQGVHTALAQIAAEELGVSWEQMQVVQSSSLGPVADGA
CCEEEEECCCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
GTSASYSVISLFPLLREMAATLREMLRTAGADQLGIAPAQTRIEQGFVVDADQPARRISF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEECCCCCHHHHHH
AELVAQPRNWETPTEAAPLTPPERWQIIGQPVPRLDLPAKIRGEAVYGYDARIEGMLYGA
HHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEECCCCEECEEEEEC
VARPPRLGAKLRRAAAGTARNRPGVVEVVIRDGFAGVVAESRLTAYAALNDLELDWELPP
CCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHEEEECCCCEEEECCCC
PFNLAELQARLAAQAGSGTVIQRQGDAAAALRGAGVIEATYQTPLAAHANLEPQAALVDV
CCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCEEEEECCCCEEECCCCCCCEEEEEC
QPDRVRAWVSTQSPVQVARTIAEVIGRKPETVEVTPTYLGGGFGRKVTTTVATEAALLSA
CHHHEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCCEEEHHHHHHHHHHHH
AVGRPVHVGWTRTEEFRYGYLRPPTYATFRATLTDDGRIAALVQHHVSGNVLFDLFPPPL
HCCCCEEECCCCCHHCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHCCCCEEEECCCCHH
RWLFGSDFGGWRGARLIYDIPNLEVKAQTVDLPVPTGPWRGLGLLANVFAVESFIDELAV
HHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAGSDPLDFRLRHLPDTATGNRFRAALEAVAAMAGWYDQPPPGRARGIACSIDAGTIAAH
HCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHH
VAEVGLVEGRLRVYRVWAAVDPGVAINPDGLAAQTEGGIMMGLSAALFEQITIADGRIEA
HHHHHHHCCCEEEEEEEEECCCCCEECCCCCCEECCCCEEEHHHHHHHHHEEEECCEEEC
GNFDRYPLLTIADAPEVFVQILRSGDQPFGGGEPPMGPIAAAVANALARLTGERRRQWPL
CCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]