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The map label for this gene is rsbU [H]

Identifier: 222525075

GI number: 222525075

Start: 2290697

End: 2291818

Strand: Direct

Name: rsbU [H]

Synonym: Chy400_1812

Alternate gene names: 222525075

Gene position: 2290697-2291818 (Clockwise)

Preceding gene: 222525074

Following gene: 222525076

Centisome position: 43.48

GC content: 56.86

Gene sequence:

>1122_bases
ATGCCCGTCCGTCATGATCGTCTGCTGCCAGCACTGCCCACACGGCGCCGGGTCTGGCCGAGTCTGTTAAGTCATCGCCA
GCGCAGACGAATAGTTGTGCCAAAACGTCAGTCGCCAGGAGAACCTGCTCTTCATGAACCGGTAGTCGATGAGGCTGCCC
AGCAGCGTGCCCGTGAGATTGAACAGGAGTTGCAGCTTGCCCGTGATATTCAGCAGGGCCTCTTGCTAGAGGCGGCGCCT
CATCTCCCCGGCTGGGAAGTGACGGCGATCTCATTGCCGGCTCGTGATTTAGGTGGTGACCTCTACGATTTTCTCCCTCT
GGCTAATGGCCTGCACGGCATCATGATCGGTGATGTCAGCGGCAAAGGTTTGCCTGCAGCTCTGCGTATGGCCGTGGCAC
GTACCGTCTTTCGCCACGAAGCCCGTCGGTATGCCGATCCGGCATCGACGATAGCTGCCGTAAATCGTGGTATCTTGAGC
GAAATTCCGCATGGCATGGTCACGATGCTGTATCTGCACCTTGAACCGCATACGGGAGCGGTACGTTGTGCGAATGCCGG
TCATACCTTTCCGTTGTTGATTACCGATACGATCCAGGAGCTAGAGATCAGCGGCTTACCATTAGGGGTTGATAGCGAGA
GCGAATATACCGAATTGAATGCGGTCATTGCACCGGGTGAAAGCCTGCTGTTGTACACCGATGGTCTGATCGAAGCCACC
CGTGCGGATGGTGCGATTTTGGGTTTCGAGCGTCTGGTCGAACTGATAATGGTTCAGCCACAGCGTAAGCCTCGTGCGCT
AGCTGCGGCATTGGTGCAAGAGGTTCGTACCTGGACGAATGGTGTGCTCAGTGATGATGTGACCCTCGTGATCCTGCGGC
GGCGGTTGCTCGATCTGGCAGCCGAAATGCGCAGCGTAATTGTCGATGTGATTGGGAGCGAGGCCATGCACACGCTTTGG
GCAACGGCTTTTGCCGATGGGGTGCCGGCTACAGTTGAAGCATGGCGCGAGCGTCTGCCTCAATTACAATCACTGGCCCA
GGCTCAGTTTGGACGTGGTCTGGCCCGCGAGCTATTGCAACAGATACGACTGACGCTCGATGACTATCGCGAGCATGTTT
GA

Upstream 100 bases:

>100_bases
AAACAATCTACCACCTGATCAGCTTCTGGAAGGGGTTGCAGTACAATGGCTGATTGAGAGTTGCCGGCGTTGGATCGGCC
GGCTTGAGGGAGAGCGTTAA

Downstream 100 bases:

>100_bases
GCGAGTGAACGTAGGTGATTCCATCAGAGTTAGTAGCCATCTCATCCATCCACCAAGAGCGCGACCGCCAGAAGATCACG
TTGCGGCGAGAATACCGTTG

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPVRHDRLLPALPTRRRVWPSLLSHRQRRRIVVPKRQSPGEPALHEPVVDEAAQQRAREIEQELQLARDIQQGLLLEAAP
HLPGWEVTAISLPARDLGGDLYDFLPLANGLHGIMIGDVSGKGLPAALRMAVARTVFRHEARRYADPASTIAAVNRGILS
EIPHGMVTMLYLHLEPHTGAVRCANAGHTFPLLITDTIQELEISGLPLGVDSESEYTELNAVIAPGESLLLYTDGLIEAT
RADGAILGFERLVELIMVQPQRKPRALAAALVQEVRTWTNGVLSDDVTLVILRRRLLDLAAEMRSVIVDVIGSEAMHTLW
ATAFADGVPATVEAWRERLPQLQSLAQAQFGRGLARELLQQIRLTLDDYREHV

Sequences:

>Translated_373_residues
MPVRHDRLLPALPTRRRVWPSLLSHRQRRRIVVPKRQSPGEPALHEPVVDEAAQQRAREIEQELQLARDIQQGLLLEAAP
HLPGWEVTAISLPARDLGGDLYDFLPLANGLHGIMIGDVSGKGLPAALRMAVARTVFRHEARRYADPASTIAAVNRGILS
EIPHGMVTMLYLHLEPHTGAVRCANAGHTFPLLITDTIQELEISGLPLGVDSESEYTELNAVIAPGESLLLYTDGLIEAT
RADGAILGFERLVELIMVQPQRKPRALAAALVQEVRTWTNGVLSDDVTLVILRRRLLDLAAEMRSVIVDVIGSEAMHTLW
ATAFADGVPATVEAWRERLPQLQSLAQAQFGRGLARELLQQIRLTLDDYREHV
>Mature_372_residues
PVRHDRLLPALPTRRRVWPSLLSHRQRRRIVVPKRQSPGEPALHEPVVDEAAQQRAREIEQELQLARDIQQGLLLEAAPH
LPGWEVTAISLPARDLGGDLYDFLPLANGLHGIMIGDVSGKGLPAALRMAVARTVFRHEARRYADPASTIAAVNRGILSE
IPHGMVTMLYLHLEPHTGAVRCANAGHTFPLLITDTIQELEISGLPLGVDSESEYTELNAVIAPGESLLLYTDGLIEATR
ADGAILGFERLVELIMVQPQRKPRALAAALVQEVRTWTNGVLSDDVTLVILRRRLLDLAAEMRSVIVDVIGSEAMHTLWA
TAFADGVPATVEAWRERLPQLQSLAQAQFGRGLARELLQQIRLTLDDYREHV

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 41260; Mature: 41129

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVRHDRLLPALPTRRRVWPSLLSHRQRRRIVVPKRQSPGEPALHEPVVDEAAQQRAREI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
EQELQLARDIQQGLLLEAAPHLPGWEVTAISLPARDLGGDLYDFLPLANGLHGIMIGDVS
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHCCHHHHHHHHHCCCCEEEEECCC
GKGLPAALRMAVARTVFRHEARRYADPASTIAAVNRGILSEIPHGMVTMLYLHLEPHTGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHEEHHEEECCCCCC
VRCANAGHTFPLLITDTIQELEISGLPLGVDSESEYTELNAVIAPGESLLLYTDGLIEAT
EEECCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHEEECCCCEEEEEECCHHHHH
RADGAILGFERLVELIMVQPQRKPRALAAALVQEVRTWTNGVLSDDVTLVILRRRLLDLA
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AEMRSVIVDVIGSEAMHTLWATAFADGVPATVEAWRERLPQLQSLAQAQFGRGLARELLQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QIRLTLDDYREHV
HHHHHHHHHHCCC
>Mature Secondary Structure 
PVRHDRLLPALPTRRRVWPSLLSHRQRRRIVVPKRQSPGEPALHEPVVDEAAQQRAREI
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
EQELQLARDIQQGLLLEAAPHLPGWEVTAISLPARDLGGDLYDFLPLANGLHGIMIGDVS
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHCCHHHHHHHHHCCCCEEEEECCC
GKGLPAALRMAVARTVFRHEARRYADPASTIAAVNRGILSEIPHGMVTMLYLHLEPHTGA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHEEHHEEECCCCCC
VRCANAGHTFPLLITDTIQELEISGLPLGVDSESEYTELNAVIAPGESLLLYTDGLIEAT
EEECCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHEEECCCCEEEEEECCHHHHH
RADGAILGFERLVELIMVQPQRKPRALAAALVQEVRTWTNGVLSDDVTLVILRRRLLDLA
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AEMRSVIVDVIGSEAMHTLWATAFADGVPATVEAWRERLPQLQSLAQAQFGRGLARELLQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
QIRLTLDDYREHV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]