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The map label for this gene is frzF [H]

Identifier: 222525074

GI number: 222525074

Start: 2289278

End: 2290696

Strand: Direct

Name: frzF [H]

Synonym: Chy400_1811

Alternate gene names: 222525074

Gene position: 2289278-2290696 (Clockwise)

Preceding gene: 222525073

Following gene: 222525075

Centisome position: 43.45

GC content: 57.08

Gene sequence:

>1419_bases
ATGACGCTATCTACAGAAGCTCTTGTTCCGCTTCGCGATTTGCTGGCGCGCTATTGTGGCGTCCTGCTCGATGATGCGCG
TCTGGTTACCCTCCGCAGTGCGGTGGAACGACGGGCGGCGGCGGCGGCTCGCACACCGGCGCGCTACCTGGCCGATCTGG
TGTTAGATGCTGACCGGACTGAGTTACAACAACTGGCCGAATTGCTCCTCAATCACGAGACAATCTTCTTCCGCAATCGT
CCGCACATGGACGCCTTACGTAAAACGTTGTTGCCGTCATTGCATGCCACGCTGCCACCGGGGATGCCGATCAAAATCTG
GAGCGCCGGGTGTGCTACCGGTGAAGAACCATATTCGATAGCCATAACTGCGCTGGAAGCTCTCGGCGATCCCCTCCCAC
GTCCAGTTTCGATTCTGGCGACCGATCTCAGTGCGTCGGCATTGGCAAAGGCCCGGCAGGGAGTGTACCGCGGGCGAACG
ATCTCCAATCTGACTCCGGCCCAACGCGCGCGCTTCTTTACCACCACCGATGCTGGCCTGTCGATTCACGAACGGGTACG
GCAACTGGTCACATTTGTCCAACATAATCTGCTCGAACCCTTTCCGGCAGCGGCTTATGGCACTCATATCCTCTTTTGTC
AAAATGTAACGATCTACTTTTCGCTTGATACCTGTCGTAGCCTGATGGCCCGCTTCTACGATGCACTGGCAGATGGCGGC
ATCCTGTGCCTTGGCTTCTCCGAAACGCTCTGGAACATTTTCGACCGCCTGACACCGGTTGCTGTTGATGGTGCATTTCT
GTATCGCAAAGATCCGCCGCCGGCCCGGTGGATGCCGACGACCACCGGTCAACGGTTGCCGGCACCGGCTCTGCGTACTC
GTGCGCCGCGTCCGCTCGAACGAAAAGTGACATTATTTACCGAGGAAGCCGTCGTTCAGGAAGGTCGCCAGTTGATCGAA
AATGGCCAAATCGATACAGCACTGGAATTATTCGCCCGTGTGCCATTGGCCGGTCGTCATGCACCCATGGTGTTGGCTCT
TGCTGCCCAGGCCCATGCCAATCGCGGCGATCTCGATCTGGCCTTGGCCGAAGCACGGCGTGCGCTGGAGCTGAATCCAC
TACTGACCGAGGCGTATCTCTTGCTGGGTTTGATCTATGAGCGACAACAACAAATGCCTCTTGCCATTCGGCACCTGGAG
CGGGCACGGTATTTGAACCGCGACCATCCATTGGTGGCCTTCCATCTGGCCGAGTGCTACCGTCAGAACCGACAGATCAC
CGAGGCTATCCGCGAATATCGAAATGCTGAACGCTTATTAAACAATCTACCACCTGATCAGCTTCTGGAAGGGGTTGCAG
TACAATGGCTGATTGAGAGTTGCCGGCGTTGGATCGGCCGGCTTGAGGGAGAGCGTTAA

Upstream 100 bases:

>100_bases
CTCGTGCGGCGATTGAGTTGGGTGCTGCCGAGCTGGTCTTGTCACCCGAAGAGATGATAGTGGTATTGAGCGAGCGTTTT
GCCGGATCTGCGAGTATGCC

Downstream 100 bases:

>100_bases
ATGCCCGTCCGTCATGATCGTCTGCTGCCAGCACTGCCCACACGGCGCCGGGTCTGGCCGAGTCTGTTAAGTCATCGCCA
GCGCAGACGAATAGTTGTGC

Product: CheR-type MCP methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTLSTEALVPLRDLLARYCGVLLDDARLVTLRSAVERRAAAAARTPARYLADLVLDADRTELQQLAELLLNHETIFFRNR
PHMDALRKTLLPSLHATLPPGMPIKIWSAGCATGEEPYSIAITALEALGDPLPRPVSILATDLSASALAKARQGVYRGRT
ISNLTPAQRARFFTTTDAGLSIHERVRQLVTFVQHNLLEPFPAAAYGTHILFCQNVTIYFSLDTCRSLMARFYDALADGG
ILCLGFSETLWNIFDRLTPVAVDGAFLYRKDPPPARWMPTTTGQRLPAPALRTRAPRPLERKVTLFTEEAVVQEGRQLIE
NGQIDTALELFARVPLAGRHAPMVLALAAQAHANRGDLDLALAEARRALELNPLLTEAYLLLGLIYERQQQMPLAIRHLE
RARYLNRDHPLVAFHLAECYRQNRQITEAIREYRNAERLLNNLPPDQLLEGVAVQWLIESCRRWIGRLEGER

Sequences:

>Translated_472_residues
MTLSTEALVPLRDLLARYCGVLLDDARLVTLRSAVERRAAAAARTPARYLADLVLDADRTELQQLAELLLNHETIFFRNR
PHMDALRKTLLPSLHATLPPGMPIKIWSAGCATGEEPYSIAITALEALGDPLPRPVSILATDLSASALAKARQGVYRGRT
ISNLTPAQRARFFTTTDAGLSIHERVRQLVTFVQHNLLEPFPAAAYGTHILFCQNVTIYFSLDTCRSLMARFYDALADGG
ILCLGFSETLWNIFDRLTPVAVDGAFLYRKDPPPARWMPTTTGQRLPAPALRTRAPRPLERKVTLFTEEAVVQEGRQLIE
NGQIDTALELFARVPLAGRHAPMVLALAAQAHANRGDLDLALAEARRALELNPLLTEAYLLLGLIYERQQQMPLAIRHLE
RARYLNRDHPLVAFHLAECYRQNRQITEAIREYRNAERLLNNLPPDQLLEGVAVQWLIESCRRWIGRLEGER
>Mature_471_residues
TLSTEALVPLRDLLARYCGVLLDDARLVTLRSAVERRAAAAARTPARYLADLVLDADRTELQQLAELLLNHETIFFRNRP
HMDALRKTLLPSLHATLPPGMPIKIWSAGCATGEEPYSIAITALEALGDPLPRPVSILATDLSASALAKARQGVYRGRTI
SNLTPAQRARFFTTTDAGLSIHERVRQLVTFVQHNLLEPFPAAAYGTHILFCQNVTIYFSLDTCRSLMARFYDALADGGI
LCLGFSETLWNIFDRLTPVAVDGAFLYRKDPPPARWMPTTTGQRLPAPALRTRAPRPLERKVTLFTEEAVVQEGRQLIEN
GQIDTALELFARVPLAGRHAPMVLALAAQAHANRGDLDLALAEARRALELNPLLTEAYLLLGLIYERQQQMPLAIRHLER
ARYLNRDHPLVAFHLAECYRQNRQITEAIREYRNAERLLNNLPPDQLLEGVAVQWLIESCRRWIGRLEGER

Specific function: This methyltransferase is one of the proteins required for the normal aggregation of M.xanthus cells during fruiting body formation. It is also a component of a sensory transduction pathway that controls the frequency at which cells reverse their gliding

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=273, Percent_Identity=32.6007326007326, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 52961; Mature: 52830

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION ; PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTEALVPLRDLLARYCGVLLDDARLVTLRSAVERRAAAAARTPARYLADLVLDADRT
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHH
ELQQLAELLLNHETIFFRNRPHMDALRKTLLPSLHATLPPGMPIKIWSAGCATGEEPYSI
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
AITALEALGDPLPRPVSILATDLSASALAKARQGVYRGRTISNLTPAQRARFFTTTDAGL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEECCCCC
SIHERVRQLVTFVQHNLLEPFPAAAYGTHILFCQNVTIYFSLDTCRSLMARFYDALADGG
HHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEECEEEEEEHHHHHHHHHHHHHHHCCCC
ILCLGFSETLWNIFDRLTPVAVDGAFLYRKDPPPARWMPTTTGQRLPAPALRTRAPRPLE
EEEEEHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCHH
RKVTLFTEEAVVQEGRQLIENGQIDTALELFARVPLAGRHAPMVLALAAQAHANRGDLDL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHH
ALAEARRALELNPLLTEAYLLLGLIYERQQQMPLAIRHLERARYLNRDHPLVAFHLAECY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RQNRQITEAIREYRNAERLLNNLPPDQLLEGVAVQWLIESCRRWIGRLEGER
HHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLSTEALVPLRDLLARYCGVLLDDARLVTLRSAVERRAAAAARTPARYLADLVLDADRT
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHH
ELQQLAELLLNHETIFFRNRPHMDALRKTLLPSLHATLPPGMPIKIWSAGCATGEEPYSI
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
AITALEALGDPLPRPVSILATDLSASALAKARQGVYRGRTISNLTPAQRARFFTTTDAGL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEEECCCCC
SIHERVRQLVTFVQHNLLEPFPAAAYGTHILFCQNVTIYFSLDTCRSLMARFYDALADGG
HHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEECEEEEEEHHHHHHHHHHHHHHHCCCC
ILCLGFSETLWNIFDRLTPVAVDGAFLYRKDPPPARWMPTTTGQRLPAPALRTRAPRPLE
EEEEEHHHHHHHHHHHHCCCEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCHH
RKVTLFTEEAVVQEGRQLIENGQIDTALELFARVPLAGRHAPMVLALAAQAHANRGDLDL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHH
ALAEARRALELNPLLTEAYLLLGLIYERQQQMPLAIRHLERARYLNRDHPLVAFHLAECY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RQNRQITEAIREYRNAERLLNNLPPDQLLEGVAVQWLIESCRRWIGRLEGER
HHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2168368 [H]