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The map label for this gene is rsbRA [H]

Identifier: 222525061

GI number: 222525061

Start: 2274885

End: 2276324

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_1798

Alternate gene names: 222525061

Gene position: 2274885-2276324 (Clockwise)

Preceding gene: 222525060

Following gene: 222525064

Centisome position: 43.18

GC content: 54.86

Gene sequence:

>1440_bases
ATGGAACTCCTCGCCATTCTCTTCACCATTGTTATTCTCGTCGCCAGCATTGTGTATGTTTTGTTGCAAGATTATCGGGC
AACGGCGAATCGTATTTTTGCCCTCTTTACTACCGCTTCGCTACTGTTAAGTTGTGCCGGAGCAGTGCGATTTGCCAGTC
GGAGCCAGACCGAGATATGGTTGTTGTCCGGGCTGCTGACCTCGCTGCAAGCAGCGACCTTTGGTCTGTTGATCTGGTTG
ATACTCATTCTCTTTATGCCGCATCGCTATAATCAACCGGCGATCCGTTGGGCTACGATTTCACCATACATGGTGATGGC
GATCGGTCTGGCAATTGACTGGTACGGTCGGTTTGGGTTTGTGGGCCGTGATGTCTTTCGCGAAGAGAGTGGTATTCTGA
CGTTCGTGCGTGGGCCGGCTTTTTGGCCGGTATTTGCACTCTACATCATCGGTTGTATCGTTATACCGGTGACGATGCTG
GTGACGCTCGCGGTACGTCATCCTGCCGTGCGAAGTCCGACGATCTGGCTTACCACAGGGACATTGTTAACCCTCGTGAC
CGGCTATTTCTCGCGGGAGATCGGTCTGACTGCGCTGACCTATGCCAGTCTGCTGCCTATCCATCTCTCGTTTGGTTGGG
TTACGATAAAGTATGGTCTTTTTCGGCCTTCACAGGTTGCCCTGCAAGCAGCCGTTGAACATTTGCCTGATGGGGTGTTG
GTGCTCGATGCCAAACATCGGGTACGGTTTGCCAATCGTGCTGCACAGCAATTGGTGGCGCTGGAGATAGGATGTGGTCT
GGAAGAGGTGCTACACGAGGCAGGCTTTGTCGAGCAGAATACCGTTTCCGATCATAGGCCGGGCTATCGTCGTTTTGTGC
GGGGAAATGAGCGGGTGCTTCTGCTTTCCGAAGTGGTCATTCGAGACGAGCGTGGTGGATCGAGCGTTGTGCTGTTGCGT
GATGTGACGATTGTTGAGCGGCAACAGGCCGAGCTGCTGGCGTCGCAGGCGATCCTGTCCGAACGGAGTGCAGCGCTGGA
ACGGTCCCTCGCAGAGCTTCGCCAGCGCGATGAATTATTGCGACGGTTAACGTTGCCGATCATCCCGCTCAGTTCAACGA
CGCTGGTGGTGCCTTTGATCGGGATGTTTGATGCTGAACGGTGTCAGACGCTGGTGCAGTTGATCCTGAACGAAACGGCA
GCCCGTCAGGTGCGGGTGGTGCTGATTGATGTGACTGGACTGACGGTGTTCGATCAGACGCTTGCCCACACGTTGAACCA
GCTTAACCAGGGTGCCCGGTTAATGGGAGCGCAGATTGTCCTGTGCGGAATTCGTCCCGATCTGGCTGAGGTGATGATCC
ACACCGGCTCGATGTGGGATGGCATTCGTTCCTTCGCAACGCTTCAGGACGGTGTTTCAGCGTTGCTGGTTGCCAGGTAG

Upstream 100 bases:

>100_bases
TGCCGGGCGTGGGGTCAGTTGCCAGAGGTGTGACAGAGAACTCCATGTATTCACGCCAGTTCTGCGATCAGGATAGGCAT
ATACATACACGGATAACTAC

Downstream 100 bases:

>100_bases
CCGGCAGCATGCTGATGCTAATGTTACGGTGATCGCCAGCCTAACCCGTCAAGCGCCTGCGGAACCGTCAGCCAGCCCTG
ACCGGGAAACAGCTTGGCGA

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MELLAILFTIVILVASIVYVLLQDYRATANRIFALFTTASLLLSCAGAVRFASRSQTEIWLLSGLLTSLQAATFGLLIWL
ILILFMPHRYNQPAIRWATISPYMVMAIGLAIDWYGRFGFVGRDVFREESGILTFVRGPAFWPVFALYIIGCIVIPVTML
VTLAVRHPAVRSPTIWLTTGTLLTLVTGYFSREIGLTALTYASLLPIHLSFGWVTIKYGLFRPSQVALQAAVEHLPDGVL
VLDAKHRVRFANRAAQQLVALEIGCGLEEVLHEAGFVEQNTVSDHRPGYRRFVRGNERVLLLSEVVIRDERGGSSVVLLR
DVTIVERQQAELLASQAILSERSAALERSLAELRQRDELLRRLTLPIIPLSSTTLVVPLIGMFDAERCQTLVQLILNETA
ARQVRVVLIDVTGLTVFDQTLAHTLNQLNQGARLMGAQIVLCGIRPDLAEVMIHTGSMWDGIRSFATLQDGVSALLVAR

Sequences:

>Translated_479_residues
MELLAILFTIVILVASIVYVLLQDYRATANRIFALFTTASLLLSCAGAVRFASRSQTEIWLLSGLLTSLQAATFGLLIWL
ILILFMPHRYNQPAIRWATISPYMVMAIGLAIDWYGRFGFVGRDVFREESGILTFVRGPAFWPVFALYIIGCIVIPVTML
VTLAVRHPAVRSPTIWLTTGTLLTLVTGYFSREIGLTALTYASLLPIHLSFGWVTIKYGLFRPSQVALQAAVEHLPDGVL
VLDAKHRVRFANRAAQQLVALEIGCGLEEVLHEAGFVEQNTVSDHRPGYRRFVRGNERVLLLSEVVIRDERGGSSVVLLR
DVTIVERQQAELLASQAILSERSAALERSLAELRQRDELLRRLTLPIIPLSSTTLVVPLIGMFDAERCQTLVQLILNETA
ARQVRVVLIDVTGLTVFDQTLAHTLNQLNQGARLMGAQIVLCGIRPDLAEVMIHTGSMWDGIRSFATLQDGVSALLVAR
>Mature_479_residues
MELLAILFTIVILVASIVYVLLQDYRATANRIFALFTTASLLLSCAGAVRFASRSQTEIWLLSGLLTSLQAATFGLLIWL
ILILFMPHRYNQPAIRWATISPYMVMAIGLAIDWYGRFGFVGRDVFREESGILTFVRGPAFWPVFALYIIGCIVIPVTML
VTLAVRHPAVRSPTIWLTTGTLLTLVTGYFSREIGLTALTYASLLPIHLSFGWVTIKYGLFRPSQVALQAAVEHLPDGVL
VLDAKHRVRFANRAAQQLVALEIGCGLEEVLHEAGFVEQNTVSDHRPGYRRFVRGNERVLLLSEVVIRDERGGSSVVLLR
DVTIVERQQAELLASQAILSERSAALERSLAELRQRDELLRRLTLPIIPLSSTTLVVPLIGMFDAERCQTLVQLILNETA
ARQVRVVLIDVTGLTVFDQTLAHTLNQLNQGARLMGAQIVLCGIRPDLAEVMIHTGSMWDGIRSFATLQDGVSALLVAR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 53096; Mature: 53096

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLAILFTIVILVASIVYVLLQDYRATANRIFALFTTASLLLSCAGAVRFASRSQTEIW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LLSGLLTSLQAATFGLLIWLILILFMPHRYNQPAIRWATISPYMVMAIGLAIDWYGRFGF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCC
VGRDVFREESGILTFVRGPAFWPVFALYIIGCIVIPVTMLVTLAVRHPAVRSPTIWLTTG
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHH
TLLTLVTGYFSREIGLTALTYASLLPIHLSFGWVTIKYGLFRPSQVALQAAVEHLPDGVL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECEEEEEECCCCCHHHHHHHHHHHCCCCEE
VLDAKHRVRFANRAAQQLVALEIGCGLEEVLHEAGFVEQNTVSDHRPGYRRFVRGNERVL
EEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCEE
LLSEVVIRDERGGSSVVLLRDVTIVERQQAELLASQAILSERSAALERSLAELRQRDELL
EEEHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLTLPIIPLSSTTLVVPLIGMFDAERCQTLVQLILNETAARQVRVVLIDVTGLTVFDQT
HHHCCCEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCHHHHHHH
LAHTLNQLNQGARLMGAQIVLCGIRPDLAEVMIHTGSMWDGIRSFATLQDGVSALLVAR
HHHHHHHHCCCHHHCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure
MELLAILFTIVILVASIVYVLLQDYRATANRIFALFTTASLLLSCAGAVRFASRSQTEIW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LLSGLLTSLQAATFGLLIWLILILFMPHRYNQPAIRWATISPYMVMAIGLAIDWYGRFGF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCC
VGRDVFREESGILTFVRGPAFWPVFALYIIGCIVIPVTMLVTLAVRHPAVRSPTIWLTTG
HHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHH
TLLTLVTGYFSREIGLTALTYASLLPIHLSFGWVTIKYGLFRPSQVALQAAVEHLPDGVL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECEEEEEECCCCCHHHHHHHHHHHCCCCEE
VLDAKHRVRFANRAAQQLVALEIGCGLEEVLHEAGFVEQNTVSDHRPGYRRFVRGNERVL
EEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCEE
LLSEVVIRDERGGSSVVLLRDVTIVERQQAELLASQAILSERSAALERSLAELRQRDELL
EEEHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLTLPIIPLSSTTLVVPLIGMFDAERCQTLVQLILNETAARQVRVVLIDVTGLTVFDQT
HHHCCCEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEEECCHHHHHHH
LAHTLNQLNQGARLMGAQIVLCGIRPDLAEVMIHTGSMWDGIRSFATLQDGVSALLVAR
HHHHHHHHCCCHHHCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]