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The map label for this gene is yycF [H]

Identifier: 222524928

GI number: 222524928

Start: 2092352

End: 2093089

Strand: Direct

Name: yycF [H]

Synonym: Chy400_1662

Alternate gene names: 222524928

Gene position: 2092352-2093089 (Clockwise)

Preceding gene: 222524927

Following gene: 222524929

Centisome position: 39.71

GC content: 50.27

Gene sequence:

>738_bases
ATGCCACTCTTTCATCGCACGTCACAACGGTCTGTTGATCAACCACCACCAAAGCGGCGCATTCTGGTGGCCGATGATGA
TCCTTCCATTGGCCGTCTGATCCAGACTGCACTGCCTACCCAGCAATATGAAACAACAGTGGTAGCCAACGGGCTTGAGG
CGCTAGAGGCATTTGAACGTGAGACCTACGATCTGATCTTTCTGGATGTGATGATGCCTTTCGTCGATGGCTTCGATGCG
TGCGAGCGCATTCGTGCCAAGAGTGACGTACCAATTGTGATCATTACGGCACGCGAAGGTACCGACGATATTGTGCAAGG
CTTTCGGCGCGGCGCTGACGAATATATCACCAAACCTTTCAAAGTTGCCGAATTTGTGGCCCGCGTTGAGGCTATTTTGC
GCCGGGTCGATATGCAAAAGGCGCGTACTGCCCCAACCTTCGTACAGGTAGGGGAATTGGTGATCGATGCGGCGGCACAT
AAAGTAGCAGTACGCGGCAAAGAAGTCAAATTAACACCAATGGAGTTTGAACTCCTCTACTTTCTGGCAGCAAATGCCGG
TCAGGTCTTTACCCGTGAAGTGTTATTTCGCGAGGTTTGGGGGTACGAGTACGTTGGTGAAACGAATCTGGTTGATGTTT
GTGTACGTCGTCTACGTGAAAAAGTTGAAGTTGAACCATCAAAACCAAAAATTATTACAACCGTGCGCGGGGTAGGGTAC
AAACTTGAACGGCTTTAG

Upstream 100 bases:

>100_bases
TTACCGTCGTCGGCTTGATGAAGCAGTATAACTGTACAGATAACGGCAGCAGTACGTTTCGTGAACGAATAGGTCAGTTG
TAAGTTGTTCATACACGCCT

Downstream 100 bases:

>100_bases
GCCAATAATCACCCGATCAACACCACAAGCGTCGAGTGCGGTGCTTCTGTATACCGCAGGATAGGACTATGTCTTCAGCA
GTATTTGTATCACGGCATCC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MPLFHRTSQRSVDQPPPKRRILVADDDPSIGRLIQTALPTQQYETTVVANGLEALEAFERETYDLIFLDVMMPFVDGFDA
CERIRAKSDVPIVIITAREGTDDIVQGFRRGADEYITKPFKVAEFVARVEAILRRVDMQKARTAPTFVQVGELVIDAAAH
KVAVRGKEVKLTPMEFELLYFLAANAGQVFTREVLFREVWGYEYVGETNLVDVCVRRLREKVEVEPSKPKIITTVRGVGY
KLERL

Sequences:

>Translated_245_residues
MPLFHRTSQRSVDQPPPKRRILVADDDPSIGRLIQTALPTQQYETTVVANGLEALEAFERETYDLIFLDVMMPFVDGFDA
CERIRAKSDVPIVIITAREGTDDIVQGFRRGADEYITKPFKVAEFVARVEAILRRVDMQKARTAPTFVQVGELVIDAAAH
KVAVRGKEVKLTPMEFELLYFLAANAGQVFTREVLFREVWGYEYVGETNLVDVCVRRLREKVEVEPSKPKIITTVRGVGY
KLERL
>Mature_244_residues
PLFHRTSQRSVDQPPPKRRILVADDDPSIGRLIQTALPTQQYETTVVANGLEALEAFERETYDLIFLDVMMPFVDGFDAC
ERIRAKSDVPIVIITAREGTDDIVQGFRRGADEYITKPFKVAEFVARVEAILRRVDMQKARTAPTFVQVGELVIDAAAHK
VAVRGKEVKLTPMEFELLYFLAANAGQVFTREVLFREVWGYEYVGETNLVDVCVRRLREKVEVEPSKPKIITTVRGVGYK
LERL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=34.6846846846847, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36.4444444444444, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=37.1794871794872, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=35.5555555555556, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.0396475770925, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=33.9285714285714, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=34.4978165938865, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=34.375, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=32.8888888888889, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=29.2035398230088, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=27.5555555555556, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=29.646017699115, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=26.2008733624454, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=146, Percent_Identity=30.1369863013699, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787487, Length=109, Percent_Identity=31.1926605504587, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790437, Length=137, Percent_Identity=31.3868613138686, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27848; Mature: 27716

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFHRTSQRSVDQPPPKRRILVADDDPSIGRLIQTALPTQQYETTVVANGLEALEAFER
CCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ETYDLIFLDVMMPFVDGFDACERIRAKSDVPIVIITAREGTDDIVQGFRRGADEYITKPF
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCHH
KVAEFVARVEAILRRVDMQKARTAPTFVQVGELVIDAAAHKVAVRGKEVKLTPMEFELLY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCEEEECCHHHHHHH
FLAANAGQVFTREVLFREVWGYEYVGETNLVDVCVRRLREKVEVEPSKPKIITTVRGVGY
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
KLERL
ECCCC
>Mature Secondary Structure 
PLFHRTSQRSVDQPPPKRRILVADDDPSIGRLIQTALPTQQYETTVVANGLEALEAFER
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ETYDLIFLDVMMPFVDGFDACERIRAKSDVPIVIITAREGTDDIVQGFRRGADEYITKPF
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCHHHHHCCHH
KVAEFVARVEAILRRVDMQKARTAPTFVQVGELVIDAAAHKVAVRGKEVKLTPMEFELLY
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCEEEECCHHHHHHH
FLAANAGQVFTREVLFREVWGYEYVGETNLVDVCVRRLREKVEVEPSKPKIITTVRGVGY
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
KLERL
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]