Click here to switch to the map view.

The map label for this gene is clpX [H]

Identifier: 222524927

GI number: 222524927

Start: 2090993

End: 2092282

Strand: Direct

Name: clpX [H]

Synonym: Chy400_1661

Alternate gene names: 222524927

Gene position: 2090993-2092282 (Clockwise)

Preceding gene: 222524926

Following gene: 222524928

Centisome position: 39.69

GC content: 54.88

Gene sequence:

>1290_bases
ATGAGTCGAACGCGCAATTCTGGTCGTGATCCGTATGCCTGCTCGTTCTGTGGGCGCGGACAGGATGAAGTACAACGCCT
GATCGCTGGCCCTGGTAACGTCTTTATCTGCGACGAATGTGTTGCGCTTTGCAGCGCCATCATTGCCGAAGAGAGCGATC
AGAAGGCACCAAACGCCCGTCGCAGTACCCCTCCAGGCCCGACCCGTTTACCCACCCCTCGTAAACTGCGCGAACGACTC
GACCAGTACGTGATCGGGCAGGATCGGGCAAAGATTGCGCTGGCGGTAGCGGTTTACAATCACTACAAGCGAGTACGGGC
CGGTGCCAGGATCGATGATGTTGAGATCAGTAAGAGTAATATCTTACTGATCGGGCCAACCGGTAGTGGTAAGACGTTGC
TGGCGCAAACAATGGCGCGTTTGCTCGATGTACCTTTCGCGATTGCCGATGCCACCGCTCTCACCGAAGCCGGGTATGTT
GGCGAGGATGTGGAAAATATTCTGCTTCGCCTGATACAGGCTGCTGATGGTGATCTGGAACGAGCACAAACCGGCATTAT
CTATATCGACGAGATTGACAAAATTGCTCGTAAGGCTGATAACCCCTCGATCACGCGCGATGTCTCTGGCGAGGGGGTCC
AGCAGGCGCTACTCAAAATCCTGGAAGGAGGCGTTGCCCACGTCCCACCCCTCCCCGGACGTAAACATCCGCAACAAGAG
TATATCCCGTTTGACACCACAAATGTGCTCTTTATCTGTGGCGGTGCGTTTGAGGGGATCACCAAAATTATTGCCAAACG
GCTGCGAGGAAAACAATTAATCGGCTTTGGCAGCAATCCGGTCAATCCGGTTGAAGAAGAAGGTGCGTTACTGGCTCAGA
TCACACCTGATGATCTGATGCACTTTGGCTTCATCCCGGAGTTCGTCGGTCGCCTGCCGGTGATTGTTGCGCTCGAACCG
CTCAGCCGCGAAGCCATGCTGCGCATCCTGACCGAACCGCGTAACGCGATTATCAAGCAGTATCAAAAGCTCTTCGCTCT
TGATCACTGTGAATTGGAATTTACACCTGACAGCCTGGAAGCGATTGTTGATCGCGCGATGGCTGCCCGCACCGGTGCCC
GTGCTCTGCGGAGCATTGTGGAAGAGGTGCTGCTCGATGTCATGTTTGAATTACCATCGCAAGAACACATCGGGCGCTGC
ATCGTTACGGCGGAAGTCATTCAAGGTCGCGGGCGTCCGATCCTGGTGCCGCGTGCCGATTACCGTCGTCGGCTTGATGA
AGCAGTATAA

Upstream 100 bases:

>100_bases
CGGTATTATCGATGAAATCCTCACCCGTGAGGATGTGAAGAAGTAATGACGCCCGGGTGGGAGCATGAACAGTGCCCACC
CGCTCGTCTGGAGAAATCCC

Downstream 100 bases:

>100_bases
CTGTACAGATAACGGCAGCAGTACGTTTCGTGAACGAATAGGTCAGTTGTAAGTTGTTCATACACGCCTATGCCACTCTT
TCATCGCACGTCACAACGGT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSRTRNSGRDPYACSFCGRGQDEVQRLIAGPGNVFICDECVALCSAIIAEESDQKAPNARRSTPPGPTRLPTPRKLRERL
DQYVIGQDRAKIALAVAVYNHYKRVRAGARIDDVEISKSNILLIGPTGSGKTLLAQTMARLLDVPFAIADATALTEAGYV
GEDVENILLRLIQAADGDLERAQTGIIYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVAHVPPLPGRKHPQQE
YIPFDTTNVLFICGGAFEGITKIIAKRLRGKQLIGFGSNPVNPVEEEGALLAQITPDDLMHFGFIPEFVGRLPVIVALEP
LSREAMLRILTEPRNAIIKQYQKLFALDHCELEFTPDSLEAIVDRAMAARTGARALRSIVEEVLLDVMFELPSQEHIGRC
IVTAEVIQGRGRPILVPRADYRRRLDEAV

Sequences:

>Translated_429_residues
MSRTRNSGRDPYACSFCGRGQDEVQRLIAGPGNVFICDECVALCSAIIAEESDQKAPNARRSTPPGPTRLPTPRKLRERL
DQYVIGQDRAKIALAVAVYNHYKRVRAGARIDDVEISKSNILLIGPTGSGKTLLAQTMARLLDVPFAIADATALTEAGYV
GEDVENILLRLIQAADGDLERAQTGIIYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVAHVPPLPGRKHPQQE
YIPFDTTNVLFICGGAFEGITKIIAKRLRGKQLIGFGSNPVNPVEEEGALLAQITPDDLMHFGFIPEFVGRLPVIVALEP
LSREAMLRILTEPRNAIIKQYQKLFALDHCELEFTPDSLEAIVDRAMAARTGARALRSIVEEVLLDVMFELPSQEHIGRC
IVTAEVIQGRGRPILVPRADYRRRLDEAV
>Mature_428_residues
SRTRNSGRDPYACSFCGRGQDEVQRLIAGPGNVFICDECVALCSAIIAEESDQKAPNARRSTPPGPTRLPTPRKLRERLD
QYVIGQDRAKIALAVAVYNHYKRVRAGARIDDVEISKSNILLIGPTGSGKTLLAQTMARLLDVPFAIADATALTEAGYVG
EDVENILLRLIQAADGDLERAQTGIIYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVAHVPPLPGRKHPQQEY
IPFDTTNVLFICGGAFEGITKIIAKRLRGKQLIGFGSNPVNPVEEEGALLAQITPDDLMHFGFIPEFVGRLPVIVALEPL
SREAMLRILTEPRNAIIKQYQKLFALDHCELEFTPDSLEAIVDRAMAARTGARALRSIVEEVLLDVMFELPSQEHIGRCI
VTAEVIQGRGRPILVPRADYRRRLDEAV

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=328, Percent_Identity=48.780487804878, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786642, Length=416, Percent_Identity=59.8557692307692, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1790366, Length=104, Percent_Identity=43.2692307692308, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=328, Percent_Identity=42.0731707317073, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=328, Percent_Identity=42.0731707317073, Blast_Score=264, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=37.0558375634518, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=248, Percent_Identity=38.3064516129032, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=412, Percent_Identity=38.5922330097087, Blast_Score=256, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24648291, Length=346, Percent_Identity=46.242774566474, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24648289, Length=346, Percent_Identity=46.242774566474, Blast_Score=286, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47124; Mature: 46993

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTRNSGRDPYACSFCGRGQDEVQRLIAGPGNVFICDECVALCSAIIAEESDQKAPNAR
CCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCC
RSTPPGPTRLPTPRKLRERLDQYVIGQDRAKIALAVAVYNHYKRVRAGARIDDVEISKSN
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
ILLIGPTGSGKTLLAQTMARLLDVPFAIADATALTEAGYVGEDVENILLRLIQAADGDLE
EEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAQTGIIYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVAHVPPLPGRKHPQQE
HHCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
YIPFDTTNVLFICGGAFEGITKIIAKRLRGKQLIGFGSNPVNPVEEEGALLAQITPDDLM
CCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHCCCEEEEECHHHHH
HFGFIPEFVGRLPVIVALEPLSREAMLRILTEPRNAIIKQYQKLFALDHCELEFTPDSLE
HHCCHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHH
AIVDRAMAARTGARALRSIVEEVLLDVMFELPSQEHIGRCIVTAEVIQGRGRPILVPRAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEHHHHCCCCCEEEECCHH
YRRRLDEAV
HHHHHHHCC
>Mature Secondary Structure 
SRTRNSGRDPYACSFCGRGQDEVQRLIAGPGNVFICDECVALCSAIIAEESDQKAPNAR
CCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCC
RSTPPGPTRLPTPRKLRERLDQYVIGQDRAKIALAVAVYNHYKRVRAGARIDDVEISKSN
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
ILLIGPTGSGKTLLAQTMARLLDVPFAIADATALTEAGYVGEDVENILLRLIQAADGDLE
EEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAQTGIIYIDEIDKIARKADNPSITRDVSGEGVQQALLKILEGGVAHVPPLPGRKHPQQE
HHCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
YIPFDTTNVLFICGGAFEGITKIIAKRLRGKQLIGFGSNPVNPVEEEGALLAQITPDDLM
CCCCCCCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHCCCEEEEECHHHHH
HFGFIPEFVGRLPVIVALEPLSREAMLRILTEPRNAIIKQYQKLFALDHCELEFTPDSLE
HHCCHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHH
AIVDRAMAARTGARALRSIVEEVLLDVMFELPSQEHIGRCIVTAEVIQGRGRPILVPRAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEHHHHCCCCCEEEECCHH
YRRRLDEAV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA