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The map label for this gene is clpP [H]

Identifier: 222524926

GI number: 222524926

Start: 2090273

End: 2090938

Strand: Direct

Name: clpP [H]

Synonym: Chy400_1660

Alternate gene names: 222524926

Gene position: 2090273-2090938 (Clockwise)

Preceding gene: 222524925

Following gene: 222524927

Centisome position: 39.67

GC content: 55.56

Gene sequence:

>666_bases
ATGAATTGGTCGTCTCGTTACAGTCACGATTGGCGTAGTATGCCGGGACCAGAATGGCTCTCGCAACGACCGGAACTACT
CATCCCGATGGTTGTCGAGAGCACGAGTCGCGGTGAGCGCGCTTTCGATATCTATTCACGGCTGTTGAAAGAGCGGATTG
TCATCCTGGGCACACCGATTGACGATCAGATCGCGAATCTGATCGTTGCTCAGTTGCTTTTCCTGGAGAGCGAAGACCCT
GATCGCGACATCTGGCTCTATATCAACAGTCCGGGAGGATCGGTTACCGCTGGACTCGGTATCTACGATACGATGCACCA
CATTCGTCCCGATGTAGCAACCGTCTGTGTGGGGATGGCCGGCAGTATGGCAACTCCCATCCTGGCCGGTGGTGCCAAGG
GCAAGCGGTATAGCCTGCCGCATTCAACCATTCACATGCACCCGGCCGGTGGTGGAGCGCGTGGCTACGCTCCTGATGTC
GAGATCATGGCCCGCGAGCTGCTCCGGCTCCAACAACTGGTACGTGAGCTGCTGGCGAAGGATACCGGCCAGCCCATTGA
ACGGATCGCGAAAGATTTTGACCGCGATCTCTTCATGACACCTGAACAGGCCAAAGAGTACGGTATTATCGATGAAATCC
TCACCCGTGAGGATGTGAAGAAGTAA

Upstream 100 bases:

>100_bases
GATTCCAGCCCTGCCGCTCCCGACGCAGAAGGTGCAACTGATGTTACAAATTCCGATGAACCGGTGAGCCGGTCATCGAA
CGAAGCATGAGGAGTGTCGT

Downstream 100 bases:

>100_bases
TGACGCCCGGGTGGGAGCATGAACAGTGCCCACCCGCTCGTCTGGAGAAATCCCATGAGTCGAACGCGCAATTCTGGTCG
TGATCCGTATGCCTGCTCGT

Product: endopeptidase Clp

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNWSSRYSHDWRSMPGPEWLSQRPELLIPMVVESTSRGERAFDIYSRLLKERIVILGTPIDDQIANLIVAQLLFLESEDP
DRDIWLYINSPGGSVTAGLGIYDTMHHIRPDVATVCVGMAGSMATPILAGGAKGKRYSLPHSTIHMHPAGGGARGYAPDV
EIMARELLRLQQLVRELLAKDTGQPIERIAKDFDRDLFMTPEQAKEYGIIDEILTREDVKK

Sequences:

>Translated_221_residues
MNWSSRYSHDWRSMPGPEWLSQRPELLIPMVVESTSRGERAFDIYSRLLKERIVILGTPIDDQIANLIVAQLLFLESEDP
DRDIWLYINSPGGSVTAGLGIYDTMHHIRPDVATVCVGMAGSMATPILAGGAKGKRYSLPHSTIHMHPAGGGARGYAPDV
EIMARELLRLQQLVRELLAKDTGQPIERIAKDFDRDLFMTPEQAKEYGIIDEILTREDVKK
>Mature_221_residues
MNWSSRYSHDWRSMPGPEWLSQRPELLIPMVVESTSRGERAFDIYSRLLKERIVILGTPIDDQIANLIVAQLLFLESEDP
DRDIWLYINSPGGSVTAGLGIYDTMHHIRPDVATVCVGMAGSMATPILAGGAKGKRYSLPHSTIHMHPAGGGARGYAPDV
EIMARELLRLQQLVRELLAKDTGQPIERIAKDFDRDLFMTPEQAKEYGIIDEILTREDVKK

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=189, Percent_Identity=52.9100529100529, Blast_Score=207, Evalue=7e-54,
Organism=Escherichia coli, GI1786641, Length=192, Percent_Identity=55.7291666666667, Blast_Score=238, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17538017, Length=190, Percent_Identity=47.8947368421053, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI20129427, Length=210, Percent_Identity=50.4761904761905, Blast_Score=205, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 24783; Mature: 24783

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWSSRYSHDWRSMPGPEWLSQRPELLIPMVVESTSRGERAFDIYSRLLKERIVILGTPI
CCCCCCCCCCCCCCCCHHHHCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCC
DDQIANLIVAQLLFLESEDPDRDIWLYINSPGGSVTAGLGIYDTMHHIRPDVATVCVGMA
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHCHHHHHHHHHHC
GSMATPILAGGAKGKRYSLPHSTIHMHPAGGGARGYAPDVEIMARELLRLQQLVRELLAK
CHHHCHHHCCCCCCCEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DTGQPIERIAKDFDRDLFMTPEQAKEYGIIDEILTREDVKK
CCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNWSSRYSHDWRSMPGPEWLSQRPELLIPMVVESTSRGERAFDIYSRLLKERIVILGTPI
CCCCCCCCCCCCCCCCHHHHCCCCCEEEHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCC
DDQIANLIVAQLLFLESEDPDRDIWLYINSPGGSVTAGLGIYDTMHHIRPDVATVCVGMA
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCHHHHHHHHHCHHHHHHHHHHC
GSMATPILAGGAKGKRYSLPHSTIHMHPAGGGARGYAPDVEIMARELLRLQQLVRELLAK
CHHHCHHHCCCCCCCEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
DTGQPIERIAKDFDRDLFMTPEQAKEYGIIDEILTREDVKK
CCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA