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The map label for this gene is muT4 [H]

Identifier: 222524924

GI number: 222524924

Start: 2088167

End: 2088607

Strand: Direct

Name: muT4 [H]

Synonym: Chy400_1658

Alternate gene names: 222524924

Gene position: 2088167-2088607 (Clockwise)

Preceding gene: 222524923

Following gene: 222524925

Centisome position: 39.63

GC content: 56.01

Gene sequence:

>441_bases
ATGACCAGTAGCCCCATTCGTGCCGCCGGTTGTGTTGTGCTGGCCCGTGACCCAACGGGCCGGCTTCTTGTCTTATTGAT
CCAGGATCGGCGAGGGATATGGACACTCCCAAAGGGCCATGTTGATGAAGGGGAGAGTGACGAAGAGGCCGCAGTACGTG
AAGTAGCTGAAGAGACCGGGATTCACTGCACGATTGCTGAACGGCTCGAACGGATTACCTATCCTATCTATCACCGTGGT
CGCTGGCAAGACAAACAGGTCACCTTTTTTCTCGCCAGTGCTGCACCTGAACCACCGACACCTGCCGTTGACGAAGGAAT
TCGTACCGCAGCCTGGGTGCCCCTTGACGAAGCTCCGCCCAAAATCATCTACCGCCAGATTCGCAATCTGCTCCAGCGTG
TTGCGCGCCGGCTTGGTCCGAACAAATCCAATTCACAATAG

Upstream 100 bases:

>100_bases
CTCGAATGGATTTCGCAGCAAGCCAACGCCACCCCAATGGCACAGTGGTGGGTCGAGATTGAAGCTGCCATTGGCCGCCT
GTTTGGGCTTTGAGGATTGT

Downstream 100 bases:

>100_bases
GCCCCAATCGCAACTTTTCGCCGCGTAATCTCTTCGCATAGACCAGATAGACGTGCTATAATGCACCATACAGCGCACCG
ATGTGTGCGTATTTTCGAGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MTSSPIRAAGCVVLARDPTGRLLVLLIQDRRGIWTLPKGHVDEGESDEEAAVREVAEETGIHCTIAERLERITYPIYHRG
RWQDKQVTFFLASAAPEPPTPAVDEGIRTAAWVPLDEAPPKIIYRQIRNLLQRVARRLGPNKSNSQ

Sequences:

>Translated_146_residues
MTSSPIRAAGCVVLARDPTGRLLVLLIQDRRGIWTLPKGHVDEGESDEEAAVREVAEETGIHCTIAERLERITYPIYHRG
RWQDKQVTFFLASAAPEPPTPAVDEGIRTAAWVPLDEAPPKIIYRQIRNLLQRVARRLGPNKSNSQ
>Mature_145_residues
TSSPIRAAGCVVLARDPTGRLLVLLIQDRRGIWTLPKGHVDEGESDEEAAVREVAEETGIHCTIAERLERITYPIYHRGR
WQDKQVTFFLASAAPEPPTPAVDEGIRTAAWVPLDEAPPKIIYRQIRNLLQRVARRLGPNKSNSQ

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 16359; Mature: 16228

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSPIRAAGCVVLARDPTGRLLVLLIQDRRGIWTLPKGHVDEGESDEEAAVREVAEETG
CCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHC
IHCTIAERLERITYPIYHRGRWQDKQVTFFLASAAPEPPTPAVDEGIRTAAWVPLDEAPP
CEEEHHHHHHHHCCCHHCCCCCCCCEEEEEEECCCCCCCCCCHHCCCCEEEECCCCCCCH
KIIYRQIRNLLQRVARRLGPNKSNSQ
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSSPIRAAGCVVLARDPTGRLLVLLIQDRRGIWTLPKGHVDEGESDEEAAVREVAEETG
CCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHC
IHCTIAERLERITYPIYHRGRWQDKQVTFFLASAAPEPPTPAVDEGIRTAAWVPLDEAPP
CEEEHHHHHHHHCCCHHCCCCCCCCEEEEEEECCCCCCCCCCHHCCCCEEEECCCCCCCH
KIIYRQIRNLLQRVARRLGPNKSNSQ
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]