| Definition | Chloroflexus sp. Y-400-fl chromosome, complete genome. |
|---|---|
| Accession | NC_012032 |
| Length | 5,268,950 |
Click here to switch to the map view.
The map label for this gene is relA [H]
Identifier: 222524836
GI number: 222524836
Start: 1986248
End: 1988614
Strand: Direct
Name: relA [H]
Synonym: Chy400_1563
Alternate gene names: 222524836
Gene position: 1986248-1988614 (Clockwise)
Preceding gene: 222524835
Following gene: 222524837
Centisome position: 37.7
GC content: 53.15
Gene sequence:
>2367_bases ATGGATGATGTAGCGATTACCGCTCATTCGCCAGAACTAACATTAACTTCGTCGACTCATACGAGGATGATGTCTGATTT GCCGCCATTATCGGCTGAATTGCTCAACCACCCGGTGATGTTTTCGCTTGTTGAACAACAGCAACGTCGTGGTTGTCAGG CATCACTCGAGTCGGTTCAAACAGCATTCATTAATGCATATCATTCACCTTCAGTTGAAGCTCTGATTTCCCGCCACCGA GAGTATCTCCCCTCAGCCGATTTCGATCTGATCCGCCGCTCGTATGCGTTCGCCGCTGTTGCCCACGAGGGGCAGCGACG GCAATCAGGCCAGCCGTACATTGATCATCCAATTGAAGTTGCCATCATCTTGCTCGATCTACGTCTTGACACCGAATCGA TTGCCGCGGCCCTCTTGCACGATGTGGTGGAGGACAGCGGTGTCCCGATTTCGGTCATAGAGCAATTTTTCGGTCAGCAA GTCGCCAGTCTGGTTGATGGGGTGACTAAACTCTCCGGTTACGAGAGCAAGAGTAAAGAAGAGGCACAGGCTGGCACGTA CCGAAAATTGATTATTGCGTCAGCCGACGACCCGCGGGTAGTTTTGATCAAGCTGGCCGACCGGCTCCACAATATGCGCA CTATTCACGCCACACCGCCGCAAAAGCAGCAACGGGTGGCGCGGGAAACCCTTGAAATCTATGCGCCTCTGGCCCACCGT CTTGGTATGTGGCAGATGAAATCGGAGCTAGAGGATCTGGCATTCAAAACGCTGCATCCCGACCGTTATCAGGAAATTGC CCGTGGCCTGGCCATGCGCAAAGAGGCCCGTGACCGCATTGTGCAAAAGGTCATTGCCCAATTGAAAGAGATGCTTGCCC GCGAAGGTATTAAGGCAGAGGTTACCGGGCGCTCGAAGCATATCTACTCGATCTGGCGTAAGATGGAGCGCAAAGGGGTG CCACTTGAGCGCATCTACGATCAGCTCGCCGTGCGCATTATTGTCGATGATCCCAACAACGAAGTGGGAGCATGCTATCA GGCCTTATGCGTGGTGCATGGCAAGATGAACTGGACGCCGGTGATGCAAGAGTTCGATGACTACATCGCTGCCCCCAAAG AGAGTTCTTACCGCTCCATCCATACGACCGTGATCCTGCCGGAGGGTTTGCACTGTGAAGTGCAGATTCGCTCGACGAAG ATGCACGAAGAGGCCGAACACGGGATTGCTGCCCACTGGCGTTATAAAGAGGGCTTCAATTCGCGCAGTGATCGCGATTA CGAAAACAAAATTCGCTGGTTGCGTGAACTGATCTCCTGGCGCAACGAAACTACCGACCGCGAATTTGTCGATATGTTGC GCGCCGAATTTGAAGAGCGCGTGTTTGTCTTCACACCGAAGGGTAAGATCATCGACCTGCCTGAAGGTTCAACGCCGGTC GATTTTGCCTATCGCATCCACTCCGAGGTCGGCCACCGTTGTATTGGGGCCAAGGTCAATGACCGCATGGTGCCACTTGA TTATCAGTTGCGGAATGGTGAGATTGTCGAGATTTTGACCTCGAAGAATCAACGTGGCCCCAGCCGTGACTGGCTACGTT TTGTGAAGACTCCCTCGGCCCGCAACCATATTAAGCGCTATTTCCGTCGTCTCGAACGTGAAGAGAATATTATCGCTGGC CGCGAGATGCTCGAAAAAGAGCTGAAACGCTTTGGCCTGATGCAGGTCAGTTTCGAGAAGCTGGTTGAACTGGCCGGGCC TACAGTACGTTCGGTTGAAGACCTCTTCTATCAAATTGGGGTCGATGATCTGAACGAACGAGCGTTGGTGCAGAAATTGC TCGGTGCTCAGGAGACTGCGCCGCCGCCGTCGCCACCTGCGCCGACTCAGCCCATGGCGCGAGTCAGTGCCAGCGGCGAA ATCTACCTTGAGGGTACCGGCAAAATTGCGTCACGCCTTGCCCGCTGTTGTAATCCGGTGTTCGGTGAGCCAATCGTTGG CTTTACAACTCGTGGTCGGGGAGTGACGGTTCATCGTACCGATTGTCGCACGATTCAGAATCTAAGCGCCTCTGAACGAA ATCGCTTGATGCCGGTCTGTTGGGGGAATGGTTCTGGCCCCAATCAATGGTTCCCGGTACCGTTACGCATTGAAGCGTGG GATCGGGTTGGCTTATGGCGCGATATTTCAAATGTGATTGCAGACGCCGGGATCAATATTACCGATATCAATCAGGGGAA GCGCTGGGCCAATGGGCGTACTGTGTTGAATGTCACGGTTTCGTTGCAATCGATGGCTCAACTGTCACCATTGATTGAAA AGCTTAATCGAATACCCGATGTCATTGATGTCTACCGTAAAACATGA
Upstream 100 bases:
>100_bases TCGTGTTCAGATCATACATATTGGCATTCCATGTACGTCCGGCCTGCCCATTCACTGCCTGTAAACGGCAGTGAATAGTC TGCCTGGATAGGAGCGGATT
Downstream 100 bases:
>100_bases TCATTGATCGAAATCTGATGCTAGCGGCTCTTCGTTCTGCACTGCTTGAATGGTTTGCCGGTAACGCGCGCGATCTGCCA TGGCGACGTACTCGCGATCC
Product: (p)ppGpp synthetase I SpoT/RelA
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 788; Mature: 788
Protein sequence:
>788_residues MDDVAITAHSPELTLTSSTHTRMMSDLPPLSAELLNHPVMFSLVEQQQRRGCQASLESVQTAFINAYHSPSVEALISRHR EYLPSADFDLIRRSYAFAAVAHEGQRRQSGQPYIDHPIEVAIILLDLRLDTESIAAALLHDVVEDSGVPISVIEQFFGQQ VASLVDGVTKLSGYESKSKEEAQAGTYRKLIIASADDPRVVLIKLADRLHNMRTIHATPPQKQQRVARETLEIYAPLAHR LGMWQMKSELEDLAFKTLHPDRYQEIARGLAMRKEARDRIVQKVIAQLKEMLAREGIKAEVTGRSKHIYSIWRKMERKGV PLERIYDQLAVRIIVDDPNNEVGACYQALCVVHGKMNWTPVMQEFDDYIAAPKESSYRSIHTTVILPEGLHCEVQIRSTK MHEEAEHGIAAHWRYKEGFNSRSDRDYENKIRWLRELISWRNETTDREFVDMLRAEFEERVFVFTPKGKIIDLPEGSTPV DFAYRIHSEVGHRCIGAKVNDRMVPLDYQLRNGEIVEILTSKNQRGPSRDWLRFVKTPSARNHIKRYFRRLEREENIIAG REMLEKELKRFGLMQVSFEKLVELAGPTVRSVEDLFYQIGVDDLNERALVQKLLGAQETAPPPSPPAPTQPMARVSASGE IYLEGTGKIASRLARCCNPVFGEPIVGFTTRGRGVTVHRTDCRTIQNLSASERNRLMPVCWGNGSGPNQWFPVPLRIEAW DRVGLWRDISNVIADAGINITDINQGKRWANGRTVLNVTVSLQSMAQLSPLIEKLNRIPDVIDVYRKT
Sequences:
>Translated_788_residues MDDVAITAHSPELTLTSSTHTRMMSDLPPLSAELLNHPVMFSLVEQQQRRGCQASLESVQTAFINAYHSPSVEALISRHR EYLPSADFDLIRRSYAFAAVAHEGQRRQSGQPYIDHPIEVAIILLDLRLDTESIAAALLHDVVEDSGVPISVIEQFFGQQ VASLVDGVTKLSGYESKSKEEAQAGTYRKLIIASADDPRVVLIKLADRLHNMRTIHATPPQKQQRVARETLEIYAPLAHR LGMWQMKSELEDLAFKTLHPDRYQEIARGLAMRKEARDRIVQKVIAQLKEMLAREGIKAEVTGRSKHIYSIWRKMERKGV PLERIYDQLAVRIIVDDPNNEVGACYQALCVVHGKMNWTPVMQEFDDYIAAPKESSYRSIHTTVILPEGLHCEVQIRSTK MHEEAEHGIAAHWRYKEGFNSRSDRDYENKIRWLRELISWRNETTDREFVDMLRAEFEERVFVFTPKGKIIDLPEGSTPV DFAYRIHSEVGHRCIGAKVNDRMVPLDYQLRNGEIVEILTSKNQRGPSRDWLRFVKTPSARNHIKRYFRRLEREENIIAG REMLEKELKRFGLMQVSFEKLVELAGPTVRSVEDLFYQIGVDDLNERALVQKLLGAQETAPPPSPPAPTQPMARVSASGE IYLEGTGKIASRLARCCNPVFGEPIVGFTTRGRGVTVHRTDCRTIQNLSASERNRLMPVCWGNGSGPNQWFPVPLRIEAW DRVGLWRDISNVIADAGINITDINQGKRWANGRTVLNVTVSLQSMAQLSPLIEKLNRIPDVIDVYRKT >Mature_788_residues MDDVAITAHSPELTLTSSTHTRMMSDLPPLSAELLNHPVMFSLVEQQQRRGCQASLESVQTAFINAYHSPSVEALISRHR EYLPSADFDLIRRSYAFAAVAHEGQRRQSGQPYIDHPIEVAIILLDLRLDTESIAAALLHDVVEDSGVPISVIEQFFGQQ VASLVDGVTKLSGYESKSKEEAQAGTYRKLIIASADDPRVVLIKLADRLHNMRTIHATPPQKQQRVARETLEIYAPLAHR LGMWQMKSELEDLAFKTLHPDRYQEIARGLAMRKEARDRIVQKVIAQLKEMLAREGIKAEVTGRSKHIYSIWRKMERKGV PLERIYDQLAVRIIVDDPNNEVGACYQALCVVHGKMNWTPVMQEFDDYIAAPKESSYRSIHTTVILPEGLHCEVQIRSTK MHEEAEHGIAAHWRYKEGFNSRSDRDYENKIRWLRELISWRNETTDREFVDMLRAEFEERVFVFTPKGKIIDLPEGSTPV DFAYRIHSEVGHRCIGAKVNDRMVPLDYQLRNGEIVEILTSKNQRGPSRDWLRFVKTPSARNHIKRYFRRLEREENIIAG REMLEKELKRFGLMQVSFEKLVELAGPTVRSVEDLFYQIGVDDLNERALVQKLLGAQETAPPPSPPAPTQPMARVSASGE IYLEGTGKIASRLARCCNPVFGEPIVGFTTRGRGVTVHRTDCRTIQNLSASERNRLMPVCWGNGSGPNQWFPVPLRIEAW DRVGLWRDISNVIADAGINITDINQGKRWANGRTVLNVTVSLQSMAQLSPLIEKLNRIPDVIDVYRKT
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HD domain [H]
Homologues:
Organism=Homo sapiens, GI38348360, Length=132, Percent_Identity=39.3939393939394, Blast_Score=70, Evalue=9e-12, Organism=Escherichia coli, GI1789147, Length=692, Percent_Identity=38.728323699422, Blast_Score=496, Evalue=1e-141, Organism=Escherichia coli, GI1790082, Length=710, Percent_Identity=36.3380281690141, Blast_Score=473, Evalue=1e-134, Organism=Caenorhabditis elegans, GI25143118, Length=138, Percent_Identity=34.0579710144928, Blast_Score=70, Evalue=3e-12, Organism=Drosophila melanogaster, GI24650996, Length=141, Percent_Identity=36.1702127659575, Blast_Score=74, Evalue=4e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR003607 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 89668; Mature: 89668
Theoretical pI: Translated: 8.02; Mature: 8.02
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDVAITAHSPELTLTSSTHTRMMSDLPPLSAELLNHPVMFSLVEQQQRRGCQASLESVQ CCCCEEEECCCCEEEECCHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHH TAFINAYHSPSVEALISRHREYLPSADFDLIRRSYAFAAVAHEGQRRQSGQPYIDHPIEV HHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEE AIILLDLRLDTESIAAALLHDVVEDSGVPISVIEQFFGQQVASLVDGVTKLSGYESKSKE EEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH EAQAGTYRKLIIASADDPRVVLIKLADRLHNMRTIHATPPQKQQRVARETLEIYAPLAHR HHHCCCEEEEEEECCCCCCEEHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHH LGMWQMKSELEDLAFKTLHPDRYQEIARGLAMRKEARDRIVQKVIAQLKEMLAREGIKAE CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE VTGRSKHIYSIWRKMERKGVPLERIYDQLAVRIIVDDPNNEVGACYQALCVVHGKMNWTP ECCCHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCH VMQEFDDYIAAPKESSYRSIHTTVILPEGLHCEVQIRSTKMHEEAEHGIAAHWRYKEGFN HHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEECHHHHHHHHCCCEEEEEEHHCCC SRSDRDYENKIRWLRELISWRNETTDREFVDMLRAEFEERVFVFTPKGKIIDLPEGSTPV CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCH DFAYRIHSEVGHRCIGAKVNDRMVPLDYQLRNGEIVEILTSKNQRGPSRDWLRFVKTPSA HHHHHHHHHHCCEEECCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCH RNHIKRYFRRLEREENIIAGREMLEKELKRFGLMQVSFEKLVELAGPTVRSVEDLFYQIG HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCC VDDLNERALVQKLLGAQETAPPPSPPAPTQPMARVSASGEIYLEGTGKIASRLARCCNPV CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHCCCC FGEPIVGFTTRGRGVTVHRTDCRTIQNLSASERNRLMPVCWGNGSGPNQWFPVPLRIEAW CCCCCCCEEECCCCEEEECCHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCCEEEECCH DRVGLWRDISNVIADAGINITDINQGKRWANGRTVLNVTVSLQSMAQLSPLIEKLNRIPD HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCH VIDVYRKT HHHHHHCC >Mature Secondary Structure MDDVAITAHSPELTLTSSTHTRMMSDLPPLSAELLNHPVMFSLVEQQQRRGCQASLESVQ CCCCEEEECCCCEEEECCHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHH TAFINAYHSPSVEALISRHREYLPSADFDLIRRSYAFAAVAHEGQRRQSGQPYIDHPIEV HHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCEE AIILLDLRLDTESIAAALLHDVVEDSGVPISVIEQFFGQQVASLVDGVTKLSGYESKSKE EEEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH EAQAGTYRKLIIASADDPRVVLIKLADRLHNMRTIHATPPQKQQRVARETLEIYAPLAHR HHHCCCEEEEEEECCCCCCEEHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHH LGMWQMKSELEDLAFKTLHPDRYQEIARGLAMRKEARDRIVQKVIAQLKEMLAREGIKAE CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE VTGRSKHIYSIWRKMERKGVPLERIYDQLAVRIIVDDPNNEVGACYQALCVVHGKMNWTP ECCCHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCH VMQEFDDYIAAPKESSYRSIHTTVILPEGLHCEVQIRSTKMHEEAEHGIAAHWRYKEGFN HHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEEEECHHHHHHHHCCCEEEEEEHHCCC SRSDRDYENKIRWLRELISWRNETTDREFVDMLRAEFEERVFVFTPKGKIIDLPEGSTPV CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCH DFAYRIHSEVGHRCIGAKVNDRMVPLDYQLRNGEIVEILTSKNQRGPSRDWLRFVKTPSA HHHHHHHHHHCCEEECCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCH RNHIKRYFRRLEREENIIAGREMLEKELKRFGLMQVSFEKLVELAGPTVRSVEDLFYQIG HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCC VDDLNERALVQKLLGAQETAPPPSPPAPTQPMARVSASGEIYLEGTGKIASRLARCCNPV CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCHHHHHHHHHCCCC FGEPIVGFTTRGRGVTVHRTDCRTIQNLSASERNRLMPVCWGNGSGPNQWFPVPLRIEAW CCCCCCCEEECCCCEEEECCHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCCEEEECCH DRVGLWRDISNVIADAGINITDINQGKRWANGRTVLNVTVSLQSMAQLSPLIEKLNRIPD HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCH VIDVYRKT HHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9383190; 9384377 [H]