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The map label for this gene is ilvE [H]

Identifier: 222524831

GI number: 222524831

Start: 1979936

End: 1980862

Strand: Reverse

Name: ilvE [H]

Synonym: Chy400_1558

Alternate gene names: 222524831

Gene position: 1980862-1979936 (Counterclockwise)

Preceding gene: 222524832

Following gene: 222524829

Centisome position: 37.6

GC content: 53.18

Gene sequence:

>927_bases
GTGCCCAACAATCGTTTTGCCTTCTTCAACGGCGAGATTGTCCCTATCGAGCAGGCACAGGTCAGTGTGATGACCAATGC
GCTCAATTATGGTACCGGTTGCTTTGAAGGGATACGCGGCTACTGGAACCCTGACCATCAACAGCTCTATGTCTTTTGTC
TGCGAGAACACATGGAGCGCCTCCATCGCTCGGCCCGTATCTTGATGATGAAATTACCCTACAGCACTGAAGAATTATGT
CAAATTACAATTGAGCTGTTGCGACGAGAAGCCTTTCGCGAAGATGTCTACATCCGACCACTCCTCTACAAGAGCGATCC
GGCCATTGCCGTTCAGTTGCACGGCCTGACCGACAGCTTCACAATGTTTGCCGTCGGGTTCGGACAATACCTGGCCGGTT
CAGCAATCAAAGCCTGTATTTCATCGTGGCGACGGATCGACGATAACATCATTCCCTCGCGGGCCAAAGCCTGTGGCGCC
TACCTCAATTCGGCGCTGGCGAAGAGTGAGGCGTTGCTGAACGGTTATGATGAAGCCATTGTGCTGAGTAATGATGGTCA
CGTCGCCGAGGCATCAGCAGCGAACCTCTTTATCGTGCGAAATGGAGTGTTGATCACGCCACCGACCAGTGGAGATATTC
TGGAAGGGATTACACGCCAGGTGGTGATGGAGTTAGCGCGCAATCAATTGGGCATTCCGGTGCGTGAGGCGCCAATTGAC
CGTACCGAACTCTACGTGGCCGAGGAAGCCTTCTTTTGTGGTACCGGTGCTGAGATCAAGCCTATTGTTGAGATTGACCG
GCGCCCGATAGGTGACGGGACGGTTGGGCCGATTGGGAGAATGCTGGTTAATCTCTACGCCGATGTGGTGCGTGGTCGGG
TGAAGAAATACCAGCACTGGTGTACACCGGTGTATGAACTGGCATAA

Upstream 100 bases:

>100_bases
CCACAACCGCGCAGCCAGACGGTGCATTCAGAACAGACCTACAGACCACAAGGTACAATATCCGATGTATACATCGCGCT
AACTAGAAAGGAAACAAGCC

Downstream 100 bases:

>100_bases
ATCGCTTTCCGGTTTCTTATCACTATAGCAGGTTATGAGATACAGCAGGAGCGGGTTGAGTAAACTCGCTCCTGTCGGCA
TGGATAAGCCATCAATCACC

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MPNNRFAFFNGEIVPIEQAQVSVMTNALNYGTGCFEGIRGYWNPDHQQLYVFCLREHMERLHRSARILMMKLPYSTEELC
QITIELLRREAFREDVYIRPLLYKSDPAIAVQLHGLTDSFTMFAVGFGQYLAGSAIKACISSWRRIDDNIIPSRAKACGA
YLNSALAKSEALLNGYDEAIVLSNDGHVAEASAANLFIVRNGVLITPPTSGDILEGITRQVVMELARNQLGIPVREAPID
RTELYVAEEAFFCGTGAEIKPIVEIDRRPIGDGTVGPIGRMLVNLYADVVRGRVKKYQHWCTPVYELA

Sequences:

>Translated_308_residues
MPNNRFAFFNGEIVPIEQAQVSVMTNALNYGTGCFEGIRGYWNPDHQQLYVFCLREHMERLHRSARILMMKLPYSTEELC
QITIELLRREAFREDVYIRPLLYKSDPAIAVQLHGLTDSFTMFAVGFGQYLAGSAIKACISSWRRIDDNIIPSRAKACGA
YLNSALAKSEALLNGYDEAIVLSNDGHVAEASAANLFIVRNGVLITPPTSGDILEGITRQVVMELARNQLGIPVREAPID
RTELYVAEEAFFCGTGAEIKPIVEIDRRPIGDGTVGPIGRMLVNLYADVVRGRVKKYQHWCTPVYELA
>Mature_307_residues
PNNRFAFFNGEIVPIEQAQVSVMTNALNYGTGCFEGIRGYWNPDHQQLYVFCLREHMERLHRSARILMMKLPYSTEELCQ
ITIELLRREAFREDVYIRPLLYKSDPAIAVQLHGLTDSFTMFAVGFGQYLAGSAIKACISSWRRIDDNIIPSRAKACGAY
LNSALAKSEALLNGYDEAIVLSNDGHVAEASAANLFIVRNGVLITPPTSGDILEGITRQVVMELARNQLGIPVREAPIDR
TELYVAEEAFFCGTGAEIKPIVEIDRRPIGDGTVGPIGRMLVNLYADVVRGRVKKYQHWCTPVYELA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI50658084, Length=283, Percent_Identity=25.7950530035336, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI48994963, Length=304, Percent_Identity=39.8026315789474, Blast_Score=213, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17565728, Length=279, Percent_Identity=26.5232974910394, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34434; Mature: 34303

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNNRFAFFNGEIVPIEQAQVSVMTNALNYGTGCFEGIRGYWNPDHQQLYVFCLREHMER
CCCCEEEEECCEEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LHRSARILMMKLPYSTEELCQITIELLRREAFREDVYIRPLLYKSDPAIAVQLHGLTDSF
HHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCH
TMFAVGFGQYLAGSAIKACISSWRRIDDNIIPSRAKACGAYLNSALAKSEALLNGYDEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLSNDGHVAEASAANLFIVRNGVLITPPTSGDILEGITRQVVMELARNQLGIPVREAPID
EEECCCCEECCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RTELYVAEEAFFCGTGAEIKPIVEIDRRPIGDGTVGPIGRMLVNLYADVVRGRVKKYQHW
HHHEEEECCCEEECCCCCCCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CTPVYELA
CCHHHHCC
>Mature Secondary Structure 
PNNRFAFFNGEIVPIEQAQVSVMTNALNYGTGCFEGIRGYWNPDHQQLYVFCLREHMER
CCCEEEEECCEEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LHRSARILMMKLPYSTEELCQITIELLRREAFREDVYIRPLLYKSDPAIAVQLHGLTDSF
HHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCH
TMFAVGFGQYLAGSAIKACISSWRRIDDNIIPSRAKACGAYLNSALAKSEALLNGYDEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLSNDGHVAEASAANLFIVRNGVLITPPTSGDILEGITRQVVMELARNQLGIPVREAPID
EEECCCCEECCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RTELYVAEEAFFCGTGAEIKPIVEIDRRPIGDGTVGPIGRMLVNLYADVVRGRVKKYQHW
HHHEEEECCCEEECCCCCCCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
CTPVYELA
CCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]