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The map label for this gene is mdtH [H]

Identifier: 222524832

GI number: 222524832

Start: 1980972

End: 1982186

Strand: Reverse

Name: mdtH [H]

Synonym: Chy400_1559

Alternate gene names: 222524832

Gene position: 1982186-1980972 (Counterclockwise)

Preceding gene: 222524833

Following gene: 222524831

Centisome position: 37.62

GC content: 58.44

Gene sequence:

>1215_bases
ATGAACCTCTCGCGCTCAACTCGCTATCGGGGATTGATCATCCTGATCGTCATCAACTTTATGATGTATGCCGGCTTCTT
CATGGTCATTCCCCTGGTCTCGGTACATTATGTGCAAACAATGGGTTTTGCTGCGGTGACGGTCGGGCTGGCGCTGGCAC
TTCGTCAACTCGTCCAGCAGGGGGTCAGCGTAGGCGGTGGGGTACTGTCGGATCGATTTGGCGGGCGCGGCCTGATCACC
GCCGGCGTCCTGGTGCGGGCCGTCGGCTTCGCCAGCCTGGCCTTTGCCGACACACCGCTCCTGCTCTTCGGATCAATGTT
GCTCTCGGCGCTCGGCGGTGCGCTCTTCGAGGCACCCAGTCGCGCCGGGATCGCTGCGCTAACCACGGAAGAAGAGCGGG
CGCGGGCTTTTTCCATCAACGGCGTCGGTGGTGGGCTGGGCATGGTGATTGGCCCGTTTCTCGGTGCACTGCTGCTCGAC
TACGGTTTCAGTACCGTCGCGTTGGCTGCTGCCGCCTGTTTTGCCTTCATTGGCGCGATTACACTGTTCCTGCCACCGAT
TGAAACGGCGACCGACCGTAGTCGGCTCGGTTTTGGGCTTGGGCTGGCACTGCGTGATCGGCCATTCCTTGCTTTCACTG
CCCTTCTCATGGGGTACTGGTTTATGTGGGTACAGTTGACGATTAGTTTGCCACTGGTAGGTGAACGACTGGCCAATGCT
GCCGATGCTGTGCGCTGGATTTACGGCATTAATGCAGGAATGACCGTCATCTTACAAATACCGGTCATTAGCTTATTCGA
GCGCTGGCTGCGTCCGCTTAGCATCTTAATCCTCGGCATTGCTCTGATGGCGTTTGGCCTGGGGATGGTTGCGCTGGCCG
GCTCCTTTCCACTCCTCATCGGATGTGTCATCATCTTCACCTTTGGCACTCTCCTCGCCACACCGGCGCAGCAGAGCGTG
GCAGCGGCGTTGGCCGACAAACGAGCACTCGGTTCATACTTCGGAGTCAATGCACTTGCGCTAGCGGTAGGTGGTGGACT
GGGCAATCTGAGCGGTGGCATGTTGATCGATCTGGCCGCTGCATTCAATCTGCCCGCATTGCCATGGCTGGCGTTTGCCG
GGATTGGGTTCATCAGCGCCGTTGGGCTTACAATACTCGGCAACTACTTGCAATTGCGCAGTGCAACAGCGCAACTGGTT
GGCATGCATCGCTAA

Upstream 100 bases:

>100_bases
CAAATGCCCGATGGGCCAATCGCGATTATCTGTAGCGCAGATCGTGCAGATATGGTAACGTAGGAACAGAATTGTTTGAC
TCATCAGAAAGTTAACCGAT

Downstream 100 bases:

>100_bases
CGTTAGGCGCCACAACCGCGCAGCCAGACGGTGCATTCAGAACAGACCTACAGACCACAAGGTACAATATCCGATGTATA
CATCGCGCTAACTAGAAAGG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNLSRSTRYRGLIILIVINFMMYAGFFMVIPLVSVHYVQTMGFAAVTVGLALALRQLVQQGVSVGGGVLSDRFGGRGLIT
AGVLVRAVGFASLAFADTPLLLFGSMLLSALGGALFEAPSRAGIAALTTEEERARAFSINGVGGGLGMVIGPFLGALLLD
YGFSTVALAAAACFAFIGAITLFLPPIETATDRSRLGFGLGLALRDRPFLAFTALLMGYWFMWVQLTISLPLVGERLANA
ADAVRWIYGINAGMTVILQIPVISLFERWLRPLSILILGIALMAFGLGMVALAGSFPLLIGCVIIFTFGTLLATPAQQSV
AAALADKRALGSYFGVNALALAVGGGLGNLSGGMLIDLAAAFNLPALPWLAFAGIGFISAVGLTILGNYLQLRSATAQLV
GMHR

Sequences:

>Translated_404_residues
MNLSRSTRYRGLIILIVINFMMYAGFFMVIPLVSVHYVQTMGFAAVTVGLALALRQLVQQGVSVGGGVLSDRFGGRGLIT
AGVLVRAVGFASLAFADTPLLLFGSMLLSALGGALFEAPSRAGIAALTTEEERARAFSINGVGGGLGMVIGPFLGALLLD
YGFSTVALAAAACFAFIGAITLFLPPIETATDRSRLGFGLGLALRDRPFLAFTALLMGYWFMWVQLTISLPLVGERLANA
ADAVRWIYGINAGMTVILQIPVISLFERWLRPLSILILGIALMAFGLGMVALAGSFPLLIGCVIIFTFGTLLATPAQQSV
AAALADKRALGSYFGVNALALAVGGGLGNLSGGMLIDLAAAFNLPALPWLAFAGIGFISAVGLTILGNYLQLRSATAQLV
GMHR
>Mature_404_residues
MNLSRSTRYRGLIILIVINFMMYAGFFMVIPLVSVHYVQTMGFAAVTVGLALALRQLVQQGVSVGGGVLSDRFGGRGLIT
AGVLVRAVGFASLAFADTPLLLFGSMLLSALGGALFEAPSRAGIAALTTEEERARAFSINGVGGGLGMVIGPFLGALLLD
YGFSTVALAAAACFAFIGAITLFLPPIETATDRSRLGFGLGLALRDRPFLAFTALLMGYWFMWVQLTISLPLVGERLANA
ADAVRWIYGINAGMTVILQIPVISLFERWLRPLSILILGIALMAFGLGMVALAGSFPLLIGCVIIFTFGTLLATPAQQSV
AAALADKRALGSYFGVNALALAVGGGLGNLSGGMLIDLAAAFNLPALPWLAFAGIGFISAVGLTILGNYLQLRSATAQLV
GMHR

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081828, Length=384, Percent_Identity=36.9791666666667, Blast_Score=231, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR022855
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42171; Mature: 42171

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSRSTRYRGLIILIVINFMMYAGFFMVIPLVSVHYVQTMGFAAVTVGLALALRQLVQQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSVGGGVLSDRFGGRGLITAGVLVRAVGFASLAFADTPLLLFGSMLLSALGGALFEAPS
HHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
RAGIAALTTEEERARAFSINGVGGGLGMVIGPFLGALLLDYGFSTVALAAAACFAFIGAI
CCCEEEECCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TLFLPPIETATDRSRLGFGLGLALRDRPFLAFTALLMGYWFMWVQLTISLPLVGERLANA
HHHCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ADAVRWIYGINAGMTVILQIPVISLFERWLRPLSILILGIALMAFGLGMVALAGSFPLLI
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GCVIIFTFGTLLATPAQQSVAAALADKRALGSYFGVNALALAVGGGLGNLSGGMLIDLAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AFNLPALPWLAFAGIGFISAVGLTILGNYLQLRSATAQLVGMHR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLSRSTRYRGLIILIVINFMMYAGFFMVIPLVSVHYVQTMGFAAVTVGLALALRQLVQQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVSVGGGVLSDRFGGRGLITAGVLVRAVGFASLAFADTPLLLFGSMLLSALGGALFEAPS
HHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
RAGIAALTTEEERARAFSINGVGGGLGMVIGPFLGALLLDYGFSTVALAAAACFAFIGAI
CCCEEEECCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
TLFLPPIETATDRSRLGFGLGLALRDRPFLAFTALLMGYWFMWVQLTISLPLVGERLANA
HHHCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ADAVRWIYGINAGMTVILQIPVISLFERWLRPLSILILGIALMAFGLGMVALAGSFPLLI
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GCVIIFTFGTLLATPAQQSVAAALADKRALGSYFGVNALALAVGGGLGNLSGGMLIDLAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
AFNLPALPWLAFAGIGFISAVGLTILGNYLQLRSATAQLVGMHR
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]