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The map label for this gene is rsbRA [H]

Identifier: 222524701

GI number: 222524701

Start: 1815050

End: 1815928

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_1428

Alternate gene names: 222524701

Gene position: 1815928-1815050 (Counterclockwise)

Preceding gene: 222524702

Following gene: 222524700

Centisome position: 34.46

GC content: 53.01

Gene sequence:

>879_bases
GTGGCAGATATCTTCACCGATCTACAAGACTTTCTCCTGGCCCGGCGTTCGGCAATGGAACACGCACTGGCGCAACAGGT
GCAACGTCAGAGTGCCGGTTATGCTCGCTTTAATCAGGAAGAGTTGTCATTTTCGGTAGGCACCACCATCGAATCACTGG
CGGAAGCAATTGGTACCCAAGACCTGCTACCGTTGCTGGCGTATGCAGAAGCGCTTGGTGAAGTGCGCGCTCATACCGGG
TTTTTGCTCAGCGATGTCTTGATAGCAGTCGATATCTTTCGTTCACTCATCTGGGACGTGCTGATGGCCTTTGCCGCTGA
GCGCCCGGATTGTACCGTTGACACGGTGCGCGCTATAGAAGATATGCTGGAGCAGTTTAGACGTGCTATTGTCACCAGTT
TTAGCTTTACGTACAATCAATTGCACCACCAGTTTCGCGACCAAACCGATCAGATTGAGGCTCAACAACAAACTATTCGT
GAACTGAGCACCCCCATTCTTCCGCTTTACGAAGGGATTCTGGTCGTGCCGCTGGTCGGCGCGATTGACAGTTTCCGTGC
CGGCCAGATGATGGAACGCCTGCTAACGACGGTTGCCGAACGTCAATCAGACATTGTGATCATTGATATTACCGGCGTGC
CGGTGATCGATACCGCTGTCGCGAGTTACCTCTTACAAACAGCACGGGCAGCACAGTTGATCGGTGCCCAGGTGATTCTG
GTCGGTATTGGCCCGGAAATTGCCCAGACTATCGTCCAGCTTGGCGTTGATCTTGGCCACATTCTCATTGGCGCTAATCT
GCAAAATGGGGTCGAGCTGGCATTTCGACGGCTGGGGCGGCAGATTGTGCGTAAGAGAAGCGATCATCATGAACGATGA

Upstream 100 bases:

>100_bases
ACGGAAACCTTGCCCTACGCTCCGCAGACAAGCGTGTGTTAACGGGTGTTTGACGTCGCATCCTTTCCGACGATACGTCG
TGTAGCGACAAGGAGGTCGC

Downstream 100 bases:

>100_bases
TAGTTTAGATTTGGCTGGCTTCAGAGATAAACGCACAATCTTCGCACGGCTTCTGCCCAACATTGCGATTGTGCCGCCCG
TTGCAATCGTAACTCGACTA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MADIFTDLQDFLLARRSAMEHALAQQVQRQSAGYARFNQEELSFSVGTTIESLAEAIGTQDLLPLLAYAEALGEVRAHTG
FLLSDVLIAVDIFRSLIWDVLMAFAAERPDCTVDTVRAIEDMLEQFRRAIVTSFSFTYNQLHHQFRDQTDQIEAQQQTIR
ELSTPILPLYEGILVVPLVGAIDSFRAGQMMERLLTTVAERQSDIVIIDITGVPVIDTAVASYLLQTARAAQLIGAQVIL
VGIGPEIAQTIVQLGVDLGHILIGANLQNGVELAFRRLGRQIVRKRSDHHER

Sequences:

>Translated_292_residues
MADIFTDLQDFLLARRSAMEHALAQQVQRQSAGYARFNQEELSFSVGTTIESLAEAIGTQDLLPLLAYAEALGEVRAHTG
FLLSDVLIAVDIFRSLIWDVLMAFAAERPDCTVDTVRAIEDMLEQFRRAIVTSFSFTYNQLHHQFRDQTDQIEAQQQTIR
ELSTPILPLYEGILVVPLVGAIDSFRAGQMMERLLTTVAERQSDIVIIDITGVPVIDTAVASYLLQTARAAQLIGAQVIL
VGIGPEIAQTIVQLGVDLGHILIGANLQNGVELAFRRLGRQIVRKRSDHHER
>Mature_291_residues
ADIFTDLQDFLLARRSAMEHALAQQVQRQSAGYARFNQEELSFSVGTTIESLAEAIGTQDLLPLLAYAEALGEVRAHTGF
LLSDVLIAVDIFRSLIWDVLMAFAAERPDCTVDTVRAIEDMLEQFRRAIVTSFSFTYNQLHHQFRDQTDQIEAQQQTIRE
LSTPILPLYEGILVVPLVGAIDSFRAGQMMERLLTTVAERQSDIVIIDITGVPVIDTAVASYLLQTARAAQLIGAQVILV
GIGPEIAQTIVQLGVDLGHILIGANLQNGVELAFRRLGRQIVRKRSDHHER

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 32422; Mature: 32291

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIFTDLQDFLLARRSAMEHALAQQVQRQSAGYARFNQEELSFSVGTTIESLAEAIGTQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCHH
DLLPLLAYAEALGEVRAHTGFLLSDVLIAVDIFRSLIWDVLMAFAAERPDCTVDTVRAIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DMLEQFRRAIVTSFSFTYNQLHHQFRDQTDQIEAQQQTIRELSTPILPLYEGILVVPLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AIDSFRAGQMMERLLTTVAERQSDIVIIDITGVPVIDTAVASYLLQTARAAQLIGAQVIL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VGIGPEIAQTIVQLGVDLGHILIGANLQNGVELAFRRLGRQIVRKRSDHHER
EECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADIFTDLQDFLLARRSAMEHALAQQVQRQSAGYARFNQEELSFSVGTTIESLAEAIGTQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHCHH
DLLPLLAYAEALGEVRAHTGFLLSDVLIAVDIFRSLIWDVLMAFAAERPDCTVDTVRAIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
DMLEQFRRAIVTSFSFTYNQLHHQFRDQTDQIEAQQQTIRELSTPILPLYEGILVVPLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AIDSFRAGQMMERLLTTVAERQSDIVIIDITGVPVIDTAVASYLLQTARAAQLIGAQVIL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
VGIGPEIAQTIVQLGVDLGHILIGANLQNGVELAFRRLGRQIVRKRSDHHER
EECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]