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The map label for this gene is degS [H]

Identifier: 222524697

GI number: 222524697

Start: 1807636

End: 1808697

Strand: Reverse

Name: degS [H]

Synonym: Chy400_1424

Alternate gene names: 222524697

Gene position: 1808697-1807636 (Counterclockwise)

Preceding gene: 222524699

Following gene: 222524696

Centisome position: 34.33

GC content: 55.37

Gene sequence:

>1062_bases
GTGTCAGGCGAAGAACTACAACAGCGCATCACAAACGCCATTCAGGCCTACCGCGACGAGATTGATCGCACCCGCCGTGA
AATCAACGAGGTAGAGTCGTTGTTGCGCCAGAATATGGCTGAAGTGGATCGGTTGGCGATGCGCGAAACCTCAATCGCCA
ACCGGGTACGTGATCTCGATGTCAACCTGGATCGTTACGAGAAAACCGACATCAAGACCTTCTTCAGCACGCTGATCGAA
GTGCAGATGCGCTTGCAGACCATGCGAGCGCAAGTCGATCAGTTGCAAGCCCGTCGCGAAGCCCTGCGCAACCGGCAGAG
TCTGCTGAGTGATGTGGTTGAATTGCTGGAACAGGCTGCAAGTGAGTTAGCGCGGAGTGCAAAGGTCGCCGATCTCCCCT
TCGATCCGCAGACCATGATTGCCAACATTATTCAATCGCAAGAGAGTGAACGGCTGCGCATCTCGCTCCAGATGCACGAT
GGCCCGGCCCAGGCGATGAGCAACCTGGTGCTGCGGGCTGAAATCTGCCAGCGCTTGCTTGACCGCGACCTTGATCAGGC
CCGTGCTGAACTGGTTGCCCTCAAGACAGCAGTCAATAACACGCTGCAAGAGACGCGCAAATTCATCTTCGATCTCCGAC
CAATGACCCTCGACGATCTGGGTCTGGTACCCACCCTGCGCCGCTATGTCGCTCAGGTTGCCGAAAAACACAAGATCGAC
ATTAACCTGATGGTGCAAAACCTCGACCAGCGTCTGCCAGGTCACTATGAAGTAACAATCTTCCGGTTCATTCAGGAAGC
TATCAATAATGTTGTACGCCATTCTGGGGCGACCCAGGCCCGCGTAATGCTCGAAAACAGCGACAACGTCCTTCAGATAC
TGATCGAAGACAATGGGAATGGCTTCGCAGTCAAAGAAGCGATTGCCAGCGCTGGTACCCGCAAGAACATGGGGCTGGCG
AACATGCGCCAGCAGATCGAGGTACTCTTGCAGGGCGAATTTGGTATTGAGAGTTCTATTGGTCGCGGCACGCGAGTGGC
GGCGACCGTACCGTTGCCGTGA

Upstream 100 bases:

>100_bases
TCGGCCGGGTTGCACACAAAACGTTGCATCCTCTGGCTGAACCGTCTATAATCTGAGCAGCAGAGAGACCGGTTGCACGG
GCAGCAGAGGAGAATCAGCA

Downstream 100 bases:

>100_bases
GGTTCCTCACATTGCTGTTAGTGGGCACGACGTCCGAACAGGTATCGATGTTCGGGTTATTTGACCGTATTGCGCAACTG
ATATGTTTGACAAAACCATC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSGEELQQRITNAIQAYRDEIDRTRREINEVESLLRQNMAEVDRLAMRETSIANRVRDLDVNLDRYEKTDIKTFFSTLIE
VQMRLQTMRAQVDQLQARREALRNRQSLLSDVVELLEQAASELARSAKVADLPFDPQTMIANIIQSQESERLRISLQMHD
GPAQAMSNLVLRAEICQRLLDRDLDQARAELVALKTAVNNTLQETRKFIFDLRPMTLDDLGLVPTLRRYVAQVAEKHKID
INLMVQNLDQRLPGHYEVTIFRFIQEAINNVVRHSGATQARVMLENSDNVLQILIEDNGNGFAVKEAIASAGTRKNMGLA
NMRQQIEVLLQGEFGIESSIGRGTRVAATVPLP

Sequences:

>Translated_353_residues
MSGEELQQRITNAIQAYRDEIDRTRREINEVESLLRQNMAEVDRLAMRETSIANRVRDLDVNLDRYEKTDIKTFFSTLIE
VQMRLQTMRAQVDQLQARREALRNRQSLLSDVVELLEQAASELARSAKVADLPFDPQTMIANIIQSQESERLRISLQMHD
GPAQAMSNLVLRAEICQRLLDRDLDQARAELVALKTAVNNTLQETRKFIFDLRPMTLDDLGLVPTLRRYVAQVAEKHKID
INLMVQNLDQRLPGHYEVTIFRFIQEAINNVVRHSGATQARVMLENSDNVLQILIEDNGNGFAVKEAIASAGTRKNMGLA
NMRQQIEVLLQGEFGIESSIGRGTRVAATVPLP
>Mature_352_residues
SGEELQQRITNAIQAYRDEIDRTRREINEVESLLRQNMAEVDRLAMRETSIANRVRDLDVNLDRYEKTDIKTFFSTLIEV
QMRLQTMRAQVDQLQARREALRNRQSLLSDVVELLEQAASELARSAKVADLPFDPQTMIANIIQSQESERLRISLQMHDG
PAQAMSNLVLRAEICQRLLDRDLDQARAELVALKTAVNNTLQETRKFIFDLRPMTLDDLGLVPTLRRYVAQVAEKHKIDI
NLMVQNLDQRLPGHYEVTIFRFIQEAINNVVRHSGATQARVMLENSDNVLQILIEDNGNGFAVKEAIASAGTRKNMGLAN
MRQQIEVLLQGEFGIESSIGRGTRVAATVPLP

Specific function: Member of the two-component regulatory system degS/degU. Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=200, Percent_Identity=25, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40145; Mature: 40013

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEELQQRITNAIQAYRDEIDRTRREINEVESLLRQNMAEVDRLAMRETSIANRVRDLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNLDRYEKTDIKTFFSTLIEVQMRLQTMRAQVDQLQARREALRNRQSLLSDVVELLEQAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SELARSAKVADLPFDPQTMIANIIQSQESERLRISLQMHDGPAQAMSNLVLRAEICQRLL
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
DRDLDQARAELVALKTAVNNTLQETRKFIFDLRPMTLDDLGLVPTLRRYVAQVAEKHKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCH
INLMVQNLDQRLPGHYEVTIFRFIQEAINNVVRHSGATQARVMLENSDNVLQILIEDNGN
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCC
GFAVKEAIASAGTRKNMGLANMRQQIEVLLQGEFGIESSIGRGTRVAATVPLP
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
SGEELQQRITNAIQAYRDEIDRTRREINEVESLLRQNMAEVDRLAMRETSIANRVRDLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNLDRYEKTDIKTFFSTLIEVQMRLQTMRAQVDQLQARREALRNRQSLLSDVVELLEQAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SELARSAKVADLPFDPQTMIANIIQSQESERLRISLQMHDGPAQAMSNLVLRAEICQRLL
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
DRDLDQARAELVALKTAVNNTLQETRKFIFDLRPMTLDDLGLVPTLRRYVAQVAEKHKID
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCH
INLMVQNLDQRLPGHYEVTIFRFIQEAINNVVRHSGATQARVMLENSDNVLQILIEDNGN
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCC
GFAVKEAIASAGTRKNMGLANMRQQIEVLLQGEFGIESSIGRGTRVAATVPLP
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3141378; 3141377; 9384377; 3136143 [H]