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The map label for this gene is rmlC [H]

Identifier: 222524606

GI number: 222524606

Start: 1703064

End: 1703594

Strand: Reverse

Name: rmlC [H]

Synonym: Chy400_1330

Alternate gene names: 222524606

Gene position: 1703594-1703064 (Counterclockwise)

Preceding gene: 222524607

Following gene: 222524605

Centisome position: 32.33

GC content: 55.56

Gene sequence:

>531_bases
ATGCGCTTCATTCCTACCGAATTGAAAGATGCCCACATTATCGAGTTGGAGCCACGCGAAGACAATCGTGGTTTCTTCGC
CCGGGTTTGGGCGAAAGACGAATTTGCTGAGCATGGTCTGGTTGATCGAGTGGTGCAGATGAACCTCTCGTACAACCGGG
TAGCCGGTACGCTGCGTGGTATGCACTTTCAGCACGCACCCTACGCCGAGACCAAGCTGGTGCGCTGTATCCGCGGTGCG
ATCTACGATGTGATCATCGACTTGCGCCCTGACTCACCGACATACAAGCGGTGGATTGGCGTGAAACTGACTGCTGCGAA
TCGGCTGGCGTTGTATGTTCCGGAAGGTTTTGCGCACGGCTTCCAGACCCTTGAGGACGATACGGAAGTATTCTACCAGG
TTTCGCAGTACTACACCCCCAGCGCCGAAGGTGGTGTGCGCTACGATGATCCGGCGTTCGGTATCGAGTGGCCATTACCG
GTTACCGAGATGAGCGAGAAAGACAAGCGCTGGCCGTTGTTTACCGGTTAG

Upstream 100 bases:

>100_bases
AGATCTTCGAGGCGCCGCCTTACACGCGGCTCAAGATGCTGCGTCATCTGATTGCCACCAATCAGCTTGACGCCGAACTG
TTCTGGAGGAGCTGATAACC

Downstream 100 bases:

>100_bases
CAAACGGAAACGAAATACCCCGTGAGCATTCCCAACTGCGAATATCGTTGGGGTCTATCTGAACAATGATGGGCAAGGGT
CTGACCTTTGCCCATCCGAC

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRFIPTELKDAHIIELEPREDNRGFFARVWAKDEFAEHGLVDRVVQMNLSYNRVAGTLRGMHFQHAPYAETKLVRCIRGA
IYDVIIDLRPDSPTYKRWIGVKLTAANRLALYVPEGFAHGFQTLEDDTEVFYQVSQYYTPSAEGGVRYDDPAFGIEWPLP
VTEMSEKDKRWPLFTG

Sequences:

>Translated_176_residues
MRFIPTELKDAHIIELEPREDNRGFFARVWAKDEFAEHGLVDRVVQMNLSYNRVAGTLRGMHFQHAPYAETKLVRCIRGA
IYDVIIDLRPDSPTYKRWIGVKLTAANRLALYVPEGFAHGFQTLEDDTEVFYQVSQYYTPSAEGGVRYDDPAFGIEWPLP
VTEMSEKDKRWPLFTG
>Mature_176_residues
MRFIPTELKDAHIIELEPREDNRGFFARVWAKDEFAEHGLVDRVVQMNLSYNRVAGTLRGMHFQHAPYAETKLVRCIRGA
IYDVIIDLRPDSPTYKRWIGVKLTAANRLALYVPEGFAHGFQTLEDDTEVFYQVSQYYTPSAEGGVRYDDPAFGIEWPLP
VTEMSEKDKRWPLFTG

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=177, Percent_Identity=40.6779661016949, Blast_Score=134, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=37.7906976744186, Blast_Score=106, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20359; Mature: 20359

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIPTELKDAHIIELEPREDNRGFFARVWAKDEFAEHGLVDRVVQMNLSYNRVAGTLRG
CCCCCCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHC
MHFQHAPYAETKLVRCIRGAIYDVIIDLRPDSPTYKRWIGVKLTAANRLALYVPEGFAHG
CCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCHHEEEEEEEECCCEEEEEECCHHHHH
FQTLEDDTEVFYQVSQYYTPSAEGGVRYDDPAFGIEWPLPVTEMSEKDKRWPLFTG
HHHHCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRFIPTELKDAHIIELEPREDNRGFFARVWAKDEFAEHGLVDRVVQMNLSYNRVAGTLRG
CCCCCCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHCCHHHHHHHHCCCHHHHHHHHHC
MHFQHAPYAETKLVRCIRGAIYDVIIDLRPDSPTYKRWIGVKLTAANRLALYVPEGFAHG
CCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCHHEEEEEEEECCCEEEEEECCHHHHH
FQTLEDDTEVFYQVSQYYTPSAEGGVRYDDPAFGIEWPLPVTEMSEKDKRWPLFTG
HHHHCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463; 10827167 [H]