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The map label for this gene is galE [H]

Identifier: 222524607

GI number: 222524607

Start: 1703600

End: 1704628

Strand: Reverse

Name: galE [H]

Synonym: Chy400_1331

Alternate gene names: 222524607

Gene position: 1704628-1703600 (Counterclockwise)

Preceding gene: 222524608

Following gene: 222524606

Centisome position: 32.35

GC content: 56.07

Gene sequence:

>1029_bases
ATGAAAGTCCTTTTAACCGGCAGTGGTGGCTATATCGGGATCGTTACCGCTCCTTACCTGATCGAACGTGGCCACGAGGT
CGTTGGGGTTGATACCGGCTACTACGAAAGCGGCTGGCTCTTCCACAGCGGCCAACGGCAACCGGCACTCATCGTACAGG
ATATTCGCCGCCTGACGGTGAGTGATCTGGTTGGGTTTGATGCCGTGGTACATATGGCCGAGTTATCGAATGATCCGCTC
GGCCAGCTCAATCGTGAACTGACGTTTCAGATCAATCATCAGGGGAGCGTCAAACTGGCGCAAGCGGCAAAGGCCGCCGG
CGTCACCCGCTTTGTGTATATGTCGTCGTGTTCAGTCTACGGCATTGGTGAAGAGGGTGAGATTAAAACCGAGGAATCAC
CGGTCAATCCCCAAACCGCCTATGCCGAATGTAAGGTGCTGGTTGAGCGTGATCTGGCGCAACTGGCCGATGACTCCTTC
TCACCGGTCTTTTTGCGCAACGCAACTGCGTTTGGGCCATCACCACGTCAGCGTTTCGATGTTGTACTCAACAATCTTGC
GGGCCTGGCCTGGACAACCGGTAAAATTGCGATGGTGAGCGATGGCACGCCGTGGCGACCGCTGGTACACATCCTTGATA
TTGCCCATGCGGTGGCCTGTGCCCTGGAAGCACCCCGCGAAGCGATTCACAACCAGGTTTTCAATGTTGGCGATAGCCGG
TACAATTACCGTGTGCGCGAAATTGCCGAAATTGTCGCCGAAGTCTTTCCTGGCTGTGAGCTGACGTTCGGTCGGAACGA
TGGCGATAATCGGAGCTACCGGGTTGATTTTAGTAAAATTGCCACGCGCCTCCCCGGTTTCGCCTGTCGGTATGATGCGG
TCGCCGGCGCCCGGCAATTACGCGCAGTCTTTGAGCGGATCGGTATGACACGCGAGATCTTCGAGGCGCCGCCTTACACG
CGGCTCAAGATGCTGCGTCATCTGATTGCCACCAATCAGCTTGACGCCGAACTGTTCTGGAGGAGCTGA

Upstream 100 bases:

>100_bases
GGCACCCAATGGATACCCTGCGCGACAAGAATTATCTGGAAGAACTGTGGCAGAGCGGTAAGGCACCGTGGAAGATTTGG
GCGTAAGCAGGGGGAGAACT

Downstream 100 bases:

>100_bases
TAACCATGCGCTTCATTCCTACCGAATTGAAAGATGCCCACATTATCGAGTTGGAGCCACGCGAAGACAATCGTGGTTTC
TTCGCCCGGGTTTGGGCGAA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKVLLTGSGGYIGIVTAPYLIERGHEVVGVDTGYYESGWLFHSGQRQPALIVQDIRRLTVSDLVGFDAVVHMAELSNDPL
GQLNRELTFQINHQGSVKLAQAAKAAGVTRFVYMSSCSVYGIGEEGEIKTEESPVNPQTAYAECKVLVERDLAQLADDSF
SPVFLRNATAFGPSPRQRFDVVLNNLAGLAWTTGKIAMVSDGTPWRPLVHILDIAHAVACALEAPREAIHNQVFNVGDSR
YNYRVREIAEIVAEVFPGCELTFGRNDGDNRSYRVDFSKIATRLPGFACRYDAVAGARQLRAVFERIGMTREIFEAPPYT
RLKMLRHLIATNQLDAELFWRS

Sequences:

>Translated_342_residues
MKVLLTGSGGYIGIVTAPYLIERGHEVVGVDTGYYESGWLFHSGQRQPALIVQDIRRLTVSDLVGFDAVVHMAELSNDPL
GQLNRELTFQINHQGSVKLAQAAKAAGVTRFVYMSSCSVYGIGEEGEIKTEESPVNPQTAYAECKVLVERDLAQLADDSF
SPVFLRNATAFGPSPRQRFDVVLNNLAGLAWTTGKIAMVSDGTPWRPLVHILDIAHAVACALEAPREAIHNQVFNVGDSR
YNYRVREIAEIVAEVFPGCELTFGRNDGDNRSYRVDFSKIATRLPGFACRYDAVAGARQLRAVFERIGMTREIFEAPPYT
RLKMLRHLIATNQLDAELFWRS
>Mature_342_residues
MKVLLTGSGGYIGIVTAPYLIERGHEVVGVDTGYYESGWLFHSGQRQPALIVQDIRRLTVSDLVGFDAVVHMAELSNDPL
GQLNRELTFQINHQGSVKLAQAAKAAGVTRFVYMSSCSVYGIGEEGEIKTEESPVNPQTAYAECKVLVERDLAQLADDSF
SPVFLRNATAFGPSPRQRFDVVLNNLAGLAWTTGKIAMVSDGTPWRPLVHILDIAHAVACALEAPREAIHNQVFNVGDSR
YNYRVREIAEIVAEVFPGCELTFGRNDGDNRSYRVDFSKIATRLPGFACRYDAVAGARQLRAVFERIGMTREIFEAPPYT
RLKMLRHLIATNQLDAELFWRS

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1786974, Length=320, Percent_Identity=26.5625, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37941; Mature: 37941

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLTGSGGYIGIVTAPYLIERGHEVVGVDTGYYESGWLFHSGQRQPALIVQDIRRLTV
CEEEEECCCCEEEEEECHHHHHCCCEEEEECCCEECCCCEEECCCCCCHHHHHHHHHHHH
SDLVGFDAVVHMAELSNDPLGQLNRELTFQINHQGSVKLAQAAKAAGVTRFVYMSSCSVY
HHHHHHHHHHHHHHHCCCCHHHCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEEECCEEE
GIGEEGEIKTEESPVNPQTAYAECKVLVERDLAQLADDSFSPVFLRNATAFGPSPRQRFD
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHH
VVLNNLAGLAWTTGKIAMVSDGTPWRPLVHILDIAHAVACALEAPREAIHNQVFNVGDSR
HHHHHHCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YNYRVREIAEIVAEVFPGCELTFGRNDGDNRSYRVDFSKIATRLPGFACRYDAVAGARQL
HCHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEHHHHHHHCCCCEEEHHHHHHHHHH
RAVFERIGMTREIFEAPPYTRLKMLRHLIATNQLDAELFWRS
HHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure
MKVLLTGSGGYIGIVTAPYLIERGHEVVGVDTGYYESGWLFHSGQRQPALIVQDIRRLTV
CEEEEECCCCEEEEEECHHHHHCCCEEEEECCCEECCCCEEECCCCCCHHHHHHHHHHHH
SDLVGFDAVVHMAELSNDPLGQLNRELTFQINHQGSVKLAQAAKAAGVTRFVYMSSCSVY
HHHHHHHHHHHHHHHCCCCHHHCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEEECCEEE
GIGEEGEIKTEESPVNPQTAYAECKVLVERDLAQLADDSFSPVFLRNATAFGPSPRQRFD
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHH
VVLNNLAGLAWTTGKIAMVSDGTPWRPLVHILDIAHAVACALEAPREAIHNQVFNVGDSR
HHHHHHCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
YNYRVREIAEIVAEVFPGCELTFGRNDGDNRSYRVDFSKIATRLPGFACRYDAVAGARQL
HCHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEHHHHHHHCCCCEEEHHHHHHHHHH
RAVFERIGMTREIFEAPPYTRLKMLRHLIATNQLDAELFWRS
HHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8921853; 12948626 [H]