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The map label for this gene is ntcA [H]

Identifier: 222524534

GI number: 222524534

Start: 1602154

End: 1602810

Strand: Reverse

Name: ntcA [H]

Synonym: Chy400_1258

Alternate gene names: 222524534

Gene position: 1602810-1602154 (Counterclockwise)

Preceding gene: 222524537

Following gene: 222524532

Centisome position: 30.42

GC content: 55.86

Gene sequence:

>657_bases
ATGACCTCACGGCTGCAAGAAGCGGAAGTGATCGTCTGGGATCGTTTAAGCCCTTTTGGACAGGCGCAATCCTTTCGCCG
GCACAATACAATCTACACTCCGACCCAACCGGCACAAACCCTTTACCTGCTAATGAGTGGTCAGGTTGGGTTACATCTTG
CGTCACGCGAAGGACGGCTACTCACTATGCGTGTTGTCGAAGAGCGACAGGCGTTCGGCTTGAGTGTCTTTGAGCGTGAT
GCAACCTATGATACCTTTGCCGAAGCGTTGACGCCGGTACGGGTGTTGGCGGTTCCCCGGAGTGAGGTACTGCAAGCGAT
GGCTGAAGACGGGACGCTGGCCATGGCAATGCTTGAACTTCTCGGCCAGCAACGTATGATCGTGAGCCGACGAATTGAGG
AGGTGGCCTTTAAGTCAGTTCCGGCCCGGTTGGCTTCAGTCCTCCTCGAAATGTCGGAGACGCAACAGGTGGCTGCCCCG
CAACCGAATCGCTTGCCCCGGCGCACCCATCAACAGCTTGCTGATATGATCAATGCGTATCGCGAAACCGTGACTAAGGT
CATTAATCAGTTCCGCGATGCCCGTCTGCTCGACGTGGATAGTTCCGGCATTACCCTGTTGAACCCATCCCGACTACGCG
AGCTGGCTCAGAGTTAG

Upstream 100 bases:

>100_bases
ATTTTCTTGGGCAGCACCTACCGAAACCTTATGGTACAATACAAAAGCAATGCAGAAACACAATTCCGACCGAACACCGG
GGCACGGAAAGGGAACCACA

Downstream 100 bases:

>100_bases
CGAGCAATCTCTTCAGGTGCCAGGCGCTTTTTGCGCTTGCGCATGTGCTCACGACGTACCACCAGCTTCCACCACAGGCC
AATAAGTTGAACAAAGGTGC

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTSRLQEAEVIVWDRLSPFGQAQSFRRHNTIYTPTQPAQTLYLLMSGQVGLHLASREGRLLTMRVVEERQAFGLSVFERD
ATYDTFAEALTPVRVLAVPRSEVLQAMAEDGTLAMAMLELLGQQRMIVSRRIEEVAFKSVPARLASVLLEMSETQQVAAP
QPNRLPRRTHQQLADMINAYRETVTKVINQFRDARLLDVDSSGITLLNPSRLRELAQS

Sequences:

>Translated_218_residues
MTSRLQEAEVIVWDRLSPFGQAQSFRRHNTIYTPTQPAQTLYLLMSGQVGLHLASREGRLLTMRVVEERQAFGLSVFERD
ATYDTFAEALTPVRVLAVPRSEVLQAMAEDGTLAMAMLELLGQQRMIVSRRIEEVAFKSVPARLASVLLEMSETQQVAAP
QPNRLPRRTHQQLADMINAYRETVTKVINQFRDARLLDVDSSGITLLNPSRLRELAQS
>Mature_217_residues
TSRLQEAEVIVWDRLSPFGQAQSFRRHNTIYTPTQPAQTLYLLMSGQVGLHLASREGRLLTMRVVEERQAFGLSVFERDA
TYDTFAEALTPVRVLAVPRSEVLQAMAEDGTLAMAMLELLGQQRMIVSRRIEEVAFKSVPARLASVLLEMSETQQVAAPQ
PNRLPRRTHQQLADMINAYRETVTKVINQFRDARLLDVDSSGITLLNPSRLRELAQS

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 24623; Mature: 24492

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRLQEAEVIVWDRLSPFGQAQSFRRHNTIYTPTQPAQTLYLLMSGQVGLHLASREGRL
CCCCCCHHHEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCE
LTMRVVEERQAFGLSVFERDATYDTFAEALTPVRVLAVPRSEVLQAMAEDGTLAMAMLEL
EHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCHHEEECCHHHHHHHHHCCCHHHHHHHHH
LGQQRMIVSRRIEEVAFKSVPARLASVLLEMSETQQVAAPQPNRLPRRTHQQLADMINAY
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RETVTKVINQFRDARLLDVDSSGITLLNPSRLRELAQS
HHHHHHHHHHHHCCEEEEECCCCEEEECHHHHHHHHCC
>Mature Secondary Structure 
TSRLQEAEVIVWDRLSPFGQAQSFRRHNTIYTPTQPAQTLYLLMSGQVGLHLASREGRL
CCCCCHHHEEEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCE
LTMRVVEERQAFGLSVFERDATYDTFAEALTPVRVLAVPRSEVLQAMAEDGTLAMAMLEL
EHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCHHEEECCHHHHHHHHHCCCHHHHHHHHH
LGQQRMIVSRRIEEVAFKSVPARLASVLLEMSETQQVAAPQPNRLPRRTHQQLADMINAY
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RETVTKVINQFRDARLLDVDSSGITLLNPSRLRELAQS
HHHHHHHHHHHHCCEEEEECCCCEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8366058; 8905231 [H]